anti-MLF1 Interacting Protein (MLF1IP) Anticorps

The centromere is a specialized chromatin domain, present throughout the cell cycle, that acts as a platform on which the transient assembly of the kinetochore occurs during mitosis. De plus, nous expédions MLF1IP Kits (20) et MLF1IP Protéines (8) et beaucoup plus de produits pour cette protéine.

afficher tous les anticorps Gène GeneID UniProt
MLF1IP 79682 Q71F23
MLF1IP 306464 Q4V8G7
MLF1IP 71876 Q8C4M7
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Top anti-MLF1IP Anticorps sur anticorps-enligne.fr

Showing 10 out of 77 products:

Catalogue No. Reactivité Hôte Conjugué Application Images Quantité Fournisseur Livraison Prix Détails
Boeuf (Vache) Lapin Inconjugué WB 100 μL Connectez-vous pour afficher 2 to 3 Days
$289.00
Détails
Humain Lapin Inconjugué WB 100 μL Connectez-vous pour afficher 2 to 3 Days
$289.00
Détails
Chimpanzé Lapin Inconjugué EIA, WB   0.1 mg Connectez-vous pour afficher 4 to 8 Days
$632.50
Détails
Chimpanzé Lapin Inconjugué EIA, WB   0.1 mg Connectez-vous pour afficher 4 to 8 Days
$632.50
Détails
Humain Lapin Inconjugué ELISA, IHC, IHC (p), WB Human Skin: Formalin-Fixed, Paraffin-Embedded (FFPE) Human Testis: Formalin-Fixed, Paraffin-Embedded (FFPE) 50 μg Connectez-vous pour afficher 11 to 14 Days
$484.00
Détails
Humain Lapin Inconjugué ELISA, IHC, IHC (p), WB Human Brain, Cerebellum: Formalin-Fixed, Paraffin-Embedded (FFPE) Human Heart: Formalin-Fixed, Paraffin-Embedded (FFPE) 50 μg Connectez-vous pour afficher 11 to 14 Days
$639.83
Détails
Chimpanzé Lapin Inconjugué EIA, WB   0.1 mg Connectez-vous pour afficher 4 to 8 Days
$632.50
Détails
Chimpanzé Lapin Inconjugué EIA, IF, IHC (p), WB   0.1 mg Connectez-vous pour afficher 4 to 8 Days
$632.50
Détails
Boeuf (Vache) Lapin Inconjugué ELISA, IHC, IHC (p), IP, WB Human Prostate (formalin-fixed, paraffin-embedded) stained with MLF1IP antibody ABIN214310 at 10 ug/ml followed by biotinylated goat anti-rabbit IgG secondary antibody ABIN481713, alkaline phosphatase-streptavidin and chromogen. Anti-MLF1IP / PBIP1 antibody IHC of human prostate. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 10 ug/ml. 50 μg Connectez-vous pour afficher 11 to 14 Days
$550.00
Détails
Boeuf (Vache) Lapin Inconjugué ELISA, ICC, IHC, IHC (p), WB Human Colon Adenocarcinoma (formalin-fixed, paraffin-embedded) stained with MLF1IP antibody ABIN214594 at 20 ug/ml followed by biotinylated goat anti-rabbit IgG secondary antibody ABIN481713, alkaline phosphatase-streptavidin and chromogen. Anti-MLF1IP / PBIP1 antibody IHC of human colon adenocarcinoma. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 20 ug/ml. 50 μg Connectez-vous pour afficher 11 to 14 Days
$550.00
Détails

anti-MLF1IP Anticorps mieux référencés

  1. Cow (Bovine) Polyclonal MLF1IP Primary Antibody pour IHC (p), ELISA - ABIN538476 : Kang, Park, Yu, Soung, Yun, Bang, Seong, Yu, Garfield, Veenstra, Lee: Self-regulated Plk1 recruitment to kinetochores by the Plk1-PBIP1 interaction is critical for proper chromosome segregation. dans Molecular cell 2006 (PubMed)

Plus d’anticorps contre MLF1IP partenaires d’interaction

Human MLF1 Interacting Protein (MLF1IP) interaction partners

  1. In-depth IPA analysis revealed that CENPU was associated with the HMGB1 signaling pathway. qPCR and western blot analysis demonstrated that in the HMGB1 signaling pathway, CENPU knockdown downregulated expression levels of ILB, CXCL8, RAC1 and IL1A

  2. This study provides new insights and evidences that MLF1IP over-expression plays important roles in progression of luminal breast cancer. However, the precise cellular mechanisms for MLF1IP in luminal breast cancer need to be further explored.

  3. MLF1IP promotes normal erythroid proliferation and is involved in the pathogenesis of polycythemia vera.

  4. MLF1IP significantly promotes prostate cancer cell proliferation and colony formation and significantly inhibits apoptosis without affecting cell cycle phase arrest in prostate cancer cell lines

  5. Plk1 regulates the timing of the delocalization and ultimate destruction of the PBIP1.CENP-Q complex.

  6. Data propose that CENP-P/O/R/Q/U self-assembles on kinetochores with varying stoichiometry and undergoes a pre-mitotic maturation step that could be important for kinetochores switching into the correct conformation for microtubule-attachment.

  7. Mammalian polo-like kinase 1-dependent regulation of the PBIP1-CENP-Q complex at kinetochores.

  8. CENP-U is a novel microtubule binding protein and plays an important role in kinetochore-microtubule attachment through its interaction with Hec1

  9. a possible role for MLF1IP deregulation in the genesis of erythroleukemias

  10. MLF1IP was found in glioblastomas where it was co-localized with MLF1 and nestin. Moreover, it was elevated in the contralateral brain where no tumor cells occurred, suggesting a role in glioma pathogenesis and potentially in other types of malignancies.

  11. Plk1 self-regulates the Plk1-PBIP1 interaction to timely localize to the kinetochores and promote proper chromosome segregation.

  12. Deletion mutants of MLF1IP revealed that the N-terminal bipartite nuclear localization signal (NLS) was responsible for nucleolar targeting.

Mouse (Murine) MLF1 Interacting Protein (MLF1IP) interaction partners

  1. MLF1IP transgenic mice developed polycythemia vera (PV)-like symptoms based on the analysis of hematological features, suggesting that MLF1IP is partially involved in the pathogenesis of PV.

  2. MLF1-IP expression at about 50% of its normal level is sufficient to sustain mice life and the development of their immune system without apparent abnormalities.

MLF1IP profil antigène

Profil protéine

The centromere is a specialized chromatin domain, present throughout the cell cycle, that acts as a platform on which the transient assembly of the kinetochore occurs during mitosis. All active centromeres are characterized by the presence of long arrays of nucleosomes in which CENPA (MIM 117139) replaces histone H3 (see MIM 601128). MLF1IP, or CENPU, is an additional factor required for centromere assembly (Foltz et al., 2006

Gene names and symbols associated with MLF1IP

  • centromere protein U (cenpu) anticorps
  • MLF1 interacting protein (MLF1IP) anticorps
  • centromere protein U (CENPU) anticorps
  • centromere protein U (Cenpu) anticorps
  • 1700029A22Rik anticorps
  • CENP-50 anticorps
  • CENP-U anticorps
  • CENP50 anticorps
  • CENPU anticorps
  • CENPU50 anticorps
  • KLIP1 anticorps
  • MGC147270 anticorps
  • PBIP1 anticorps

Protein level used designations for MLF1IP

MLF1 interacting protein , CENP-U , centromere protein U-like , KSHV latent nuclear antigen interacting protein 1 , KSHV latent nuclear antigen-interacting protein 1 , MLF1-interacting protein , centromere protein U , centromere protein of 50 kDa , interphase centromere complex protein 24 , polo-box-interacting protein 1 , myeloid leukemia factor 1 interacting protein , centromere protein p50

GENE ID SPECIES
780000 Xenopus (Silurana) tropicalis
100499428 Meleagris gallopavo
100435854 Pongo abelii
100586173 Nomascus leucogenys
79682 Homo sapiens
607799 Canis lupus familiaris
617866 Bos taurus
306464 Rattus norvegicus
461630 Pan troglodytes
422548 Gallus gallus
71876 Mus musculus
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