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The MUC6 gene encodes gastric mucin, a secreted glycoprotein that plays an essential role in epithelial cytoprotection from acid, proteases, pathogenic microorganisms, and mechanical trauma in the gastrointestinal tract (summary by Toribara et al., 1993.
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Cftr (Montrer CFTR Kits ELISA)-/- mice showed a higher expression of Muc6 at both protein and RNA levels compared with their control Cftr (Montrer CFTR Kits ELISA)+/+ littermates, suggesting that Muc6 may contribute to blocking of pancreatic acini and ducts in mouse models of cystic fibrosis (Montrer S100A8 Kits ELISA).
organization of the secreted gel-forming mucin (Montrer MUC2 Kits ELISA) gene cluster and the complete gene structure of its different members
transcription of the Mucin 6 gene in thymic medullary epithelial cells is indeed Aire (Montrer AIRE Kits ELISA)-dependent
The expression of MUC5AC, MUC2 (Montrer MUC2 Kits ELISA), and MUC6 mRNA in CagA (Montrer S100A8 Kits ELISA)-transfected AGS (Montrer JAG1 Kits ELISA) cells at an NH concentration of 15 mM was significantly higher than that at 0 mM, and decreased at higher concentrations. H. pylori may affect the expression of MUC5AC, MUC2 (Montrer MUC2 Kits ELISA), MUC5B, and MUC6 in AGS (Montrer JAG1 Kits ELISA) cells via CagA (Montrer S100A8 Kits ELISA) and/or NH, but not E-cadherin (Montrer CDH1 Kits ELISA).
decreased expression of alphaGlcNAc relative to MUC6 occurs early and marks the initiation of tumor progression to pancreatic cancer.
outcome, while the gain of aberrant expression of MUC5AC and particularly of MUC6 was associated with favorable outcome in colorectal cancer, notably in intermediate stages II and III
In ovarian mucinous tumors, MUC6 expression changes with the progression of benign to borderline and malignant tumours
CDX2 (Montrer CDX2 Kits ELISA), MUC1 (Montrer MUC1 Kits ELISA), MUC5AC, and MUC6 expression patterns may provide better estimations of survival after surgical resection of small intestinal adenocarcinoma.
The expression of a subset of mucins (MUC2, MUC6, MUC5B) was also correlated with sialyl-Tn expression in LS174T cells.
There was no difference in the expression of deep MUC1 (Montrer MUC1 Kits ELISA), MUC2 (Montrer MUC2 Kits ELISA), MUC5AC, or MUC6 between the groups of gastric cancer and controls.
Human TTF2 is a lectin that binds alpha-GlcNAc-capped mucin 6 g with antibiotic activity against Helicobacter pylori.
High MUC6 expression is associated with gastric carcinoma.
we report the expression pattern of MUC2 (Montrer MUC2 Kits ELISA), MUC5AC, MUC5B, and MUC6 in a large series of colorectal carcinomas
The MUC6 gene encodes gastric mucin, a secreted glycoprotein that plays an essential role in epithelial cytoprotection from acid, proteases, pathogenic microorganisms, and mechanical trauma in the gastrointestinal tract (summary by Toribara et al., 1993
mucin 6, gastric
, mucin 6, oligomeric mucus/gel-forming
, oligomeric mucus/gel-forming
, ovomucin, beta subunit
, ovomucin, beta-subunit
, gastric mucin-6
, gastric mucin-like protein
, secreted gel-forming mucin-6