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MUC7 encodes a small salivary mucin, which is thought to play a role in facilitating the clearance of bacteria in the oral cavity and to aid in mastication, speech, and swallowing.
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The genotypic polymorphisms of IL-1beta (Montrer IL1B Kits ELISA) -511 and +3954, and of MUC7 VNTR, had no direct associations with the development of BMS. However, the T allele of IL-1beta (Montrer IL1B Kits ELISA) -511 may increase the risk of BMS by increasing psychological asthenia.
High expression of MUC7 is associated with clear-cell renal cell carcinoma.
A capsule-free mutant of S. pneumoniae TIGR4 binds to salivary proteins, most prominently to mucin (Montrer SLC13A2 Kits ELISA) MUC7, but that this binding was not mediated through PsrP or recognition of sialic acid.
MUC7 glycosylation is altered in recurrent aphthous stomatitis. This may change the protective properties of this mucin (Montrer SLC13A2 Kits ELISA) against mucosal pathogens, which may effect this condition.
Results identified a reduction in glycosylation of MUC7 in Sjogren's primarily due to the loss of the extended core 2 disialylated structure, with and without fucosylation and suggest that MUC7 O-glycan changes in Sjogren's Syndrome may alter the physical properties of saliva (Montrer RAG1AP1 Kits ELISA), leading to the symptom of dry mouth.
The minimally invasive PTT procedure combined with Mucin 7 targeted GNPs is able to kill cancer cells and preserve healthy cells
MUC7 is a salivary mucin (Montrer SLC13A2 Kits ELISA) with antimicrobial activity against bacteria and fungi.
A significant increase in sulfation was identified in salivary MUC7 from rheumatoid arthritis patients.
The study did not show a correlation between the MUC7 genotypes and caries.
The present study did not disclose an association between MUC7*5/*6 and MUC7*6/*6 genotypes and gingival bleeding index.
This gene encodes a small salivary mucin, which is thought to play a role in facilitating the clearance of bacteria in the oral cavity and to aid in mastication, speech, and swallowing. The central domain of this glycoprotein contains tandem repeats, each composed of 23 amino acids. The most common allele contains 6 repeats, and some alleles may be associated with susceptibility to asthma. Alternatively spliced transcript variants with different 5' UTR, but encoding the same protein, have been found for this gene.
, mucin 7, salivary
, salivary mucin-7