Myelin Protein Zero-Like 2 Protéines (MPZL2)

Thymus development depends on a complex series of interactions between thymocytes and the stromal component of the organ. De plus, nous expédions MPZL2 Anticorps (69) et beaucoup plus de produits pour cette protéine.

afficher tous les protéines Gène GeneID UniProt
MPZL2 10205 O60487
MPZL2 14012  
Rat MPZL2 MPZL2 300679  
Comment commander chez anticorps-enligne
  • +1 877 302 8632
  • +1 888 205 9894 (toll-free)
  • Commandez enligne
  • orders@anticorps-enligne.fr

Top MPZL2 Protéines sur anticorps-enligne.fr

Showing 8 out of 10 products:

Catalogue No. Origin Source Conjugué Images Quantité Livraison Prix Détails
Cellules d'insectes Souris rho-1D4 tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 0.25 mg 50 to 55 Days
$5,262.31
Détails
Escherichia coli (E. coli) Humain His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg 30 to 35 Days
$5,370.21
Détails
Escherichia coli (E. coli) Souris His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg 30 to 35 Days
$5,370.21
Détails
Cellules d'insectes Humain rho-1D4 tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 0.5 mg 50 to 55 Days
$7,493.38
Détails
HEK-293 Cells Humain Myc-DYKDDDDK Tag Validation with Western Blot 20 μg 11 Days
$888.80
Détails
Wheat germ Humain GST tag 2 μg 11 to 12 Days
$338.33
Détails
Levure Orang-Utan His tag   1 mg 60 to 71 Days
$2,256.83
Détails
Levure Boeuf (Vache) His tag   1 mg 60 to 71 Days
$2,262.33
Détails

MPZL2 Protéines protéines par origine et source

Origin Exprimée danse Conjugué
Human , , ,
, , ,
Mouse (Murine) ,
,

Plus protéines pour Myelin Protein Zero-Like 2 (MPZL2) partenaires d'interaction

Human Myelin Protein Zero-Like 2 (MPZL2) interaction partners

  1. We show that Mpzl2 is expressed in mouse inner ear, and the protein localizes in the auditory inner and outer hair cells, with an asymmetric subcellular localization. We thus present MPZL2 as a novel gene associated with sensorineural hearing loss.

  2. CLCA2 links junctional adhesion molecule EVA1, to cytosolic signaling proteins that modulate proliferation and differentiation.

  3. Findings highlight Eva1 as a novel regulator of GIC function and also provide new mechanistic insight into the role of noncanonical NF-kappaB activation in GIC.

  4. EVA is expressed in human choroid plexus epithelial cells and CD4 T lymphocytes and regulates CD4+ T lymphocyte adhesion to human choroid plexus epithelial cells in vitro. These data suggest a novel mechanism to regulate CNS immune surveillance.

Mouse (Murine) Myelin Protein Zero-Like 2 (MPZL2) interaction partners

  1. We show that Mpzl2 is expressed in mouse inner ear, and the protein localizes in the auditory inner and outer hair cells, with an asymmetric subcellular localization. We thus present MPZL2 as a novel gene associated with sensorineural hearing loss.

  2. EVA deficiency results in increased experimental autoimmune encephalomyelitis disease severity. EVA-knockout Mice have normal immune system development and choroid plexus morphology.

  3. modulation of Eva1 expression in thymocytes is crucial for lymphocyte physiological developmental progression and stromal differentiation

  4. These results suggest that EVA expressed in choroid plexus cells may regulate the permeability of the blood-CSF barrier.

Profil protéine MPZL2

Profil protéine

Thymus development depends on a complex series of interactions between thymocytes and the stromal component of the organ. Epithelial V-like antigen (EVA) is expressed in thymus epithelium and strongly downregulated by thymocyte developmental progression. This gene is expressed in the thymus and in several epithelial structures early in embryogenesis. It is highly homologous to the myelin protein zero and, in thymus-derived epithelial cell lines, is poorly soluble in nonionic detergents, strongly suggesting an association to the cytoskeleton. Its capacity to mediate cell adhesion through a homophilic interaction and its selective regulation by T cell maturation might imply the participation of EVA in the earliest phases of thymus organogenesis. The protein bears a characteristic V-type domain and two potential N-glycosylation sites in the extracellular domain\; a putative serine phosphorylation site for casein kinase 2 is also present in the cytoplasmic tail. Two transcript variants encoding the same protein have been found for this gene.

Gene names and symbols associated with MPZL2

  • myelin protein zero-like 2b (mpzl2b)
  • myelin protein zero like 2 (MPZL2)
  • myelin protein zero-like 2 (Mpzl2)
  • cb837 Protéine
  • Eva Protéine
  • Eva1 Protéine
  • mpzl2 Protéine
  • wu:fb07b02 Protéine

Protein level used designations for MPZL2

epithelial V-like antigen 1 , myelin protein zero-like 2 , myelin protein zero-like protein 2

GENE ID SPECIES
336830 Danio rerio
419779 Gallus gallus
699330 Macaca mulatta
10205 Homo sapiens
14012 Mus musculus
300679 Rattus norvegicus
540423 Bos taurus
489384 Canis lupus familiaris
100172793 Pongo abelii
Fournisseurs de qualité sélectionnés pour MPZL2 Protéines (MPZL2)
Avez-vous cherché autre chose?