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NCAPH2 encodes one of the non-SMC subunits of the condensin II complex. De plus, nous expédions Non-SMC Condensin II Complex, Subunit H2 Protéines (5) et beaucoup plus de produits pour cette protéine.
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Human Polyclonal NCAPH2 Primary Antibody pour ELISA, WB - ABIN544772
Loftus, Kim, Sneddon, Kalush, Brandon, Fuhrmann, Mason, Crosby, Barnstead, Cronin, Deslattes Mays, Cao, Xu, Kang, Mitchell, Eichler, Harris, Venter, Adams: Genome duplications and other features in 12 Mb of DNA sequence from human chromosome 16p and 16q. dans Genomics 1999
Show all 3 Pubmed References
Data found that the abundance of CAP-H2 is increased in mitosis by a Plk1 kinase activity-dependent manner and that inhibition of Plk1 induces a degradation of CAP-H2 through Cdc20-mediated ubiquitin-proteasome machinery. These results suggest that the expression levels of CAP-H2 are regulated by Plk1 and Cdc20 for proper chromosomal organization during mitosis.
Condensin II(CAP-D3 and CAP-H2) and GAIT subunits associate with L1 RNA in a co-dependent manner, independent of IFN-gamma. These findings suggest that cooperation between the Condensin II and GAIT complexes may facilitate a novel mechanism of L1 repression, thus contributing to the maintenance of genome stability in somatic cells
Results suggest that DNA methylation in the NCAPH2/LMF2 promoter region is associated with hippocampal atrophy through apoptosis
DNA methylation in the NCAPH2/LMF2 promoter region is significantly decreased in Alzheimer disease.
CAPH2 protein accumulates as cells approach senescence, and knockdown of CAPH2 inhibits senescence.
The CAP-H2 subunit of the condensin II complex implicated in chromosome assembly and segregation
mice inheriting missense mutations in a condensin II subunit (Caph2(nes)) develop T-cell lymphoma
Condensins I and II have overlapping and non-overlapping functions in Neural stem cells.
condensin II (beta-kleisin) has an essential role during meiosis I in mouse oocytes and its function overlaps with that of condensin I (gamma-kleisin), which is otherwise redundant
We confirm that Ncaph2 can generate three different N-termini, all encoded by exon 1, one of which is translated from an alternative reading frame.
define a unique lineage-specific requirement for kleisin beta in mammalian T cell differentiation
This gene encodes one of the non-SMC subunits of the condensin II complex. This complex plays an essential role in mitotic chromosome assembly. Alternate splicing of this gene results in multiple transcript variants.
non-SMC condensin II complex, subunit H2
, kleisin beta
, condensin-2 complex subunit H2
, condensin-2 complex subunit H2-like
, CAP-H2 subunit of the condensin II complex
, chromosome-associated protein H2
, non-SMC condensin II complex subunit H2