anti-Oxysterol Binding Protein-Like 8 (OSBPL8) Anticorps

OSBPL8 encodes a member of the oxysterol-binding protein (OSBP) family, a group of intracellular lipid receptors. De plus, nous expédions Oxysterol Binding Protein-Like 8 Kits (6) et Oxysterol Binding Protein-Like 8 Protéines (4) et beaucoup plus de produits pour cette protéine.

afficher tous les anticorps Gène GeneID UniProt
OSBPL8 314824  
OSBPL8 114882 Q9BZF1
OSBPL8 237542  
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Top anti-Oxysterol Binding Protein-Like 8 Anticorps sur anticorps-enligne.fr

Showing 10 out of 20 products:

Catalogue No. Reactivité Hôte Conjugué Application Images Quantité Fournisseur Livraison Prix Détails
Boeuf (Vache) Lapin Inconjugué IHC, WB <b>WB Suggested Anti-OSBPL8 Antibody Titration: </b>0.2-1 ug/ml<br><b>ELISA Titer: </b>1:1562500<br><b>Positive Control: </b>721_B cell lysate 100 μL Connectez-vous pour afficher 2 to 3 Days
$289.00
Détails
Boeuf (Vache) Lapin Inconjugué WB <b>WB Suggested Anti-OSBPL8 Antibody Titration: </b>0.2-1 ug/ml<br><b>Positive Control: </b>OVCAR-3 cell lysate Host: Rabbit  <br /> Target Name: OSBPL8  <br /> Sample Tissue: OVCAR-3 <br /> Antibody Dilution: 1.0 µg/mL OSBPL8 is strongly supported by BioGPS gene expression data to be expressed in OVCAR3 100 μL Connectez-vous pour afficher 2 to 3 Days
$289.00
Détails
Boeuf (Vache) Lapin Inconjugué WB 50 μg Connectez-vous pour afficher 7 to 9 Days
$551.83
Détails
Humain Lapin Inconjugué WB 50 μg Connectez-vous pour afficher 7 to 9 Days
$551.83
Détails
Humain Lapin Inconjugué ICC, IF, WB Immunocytochemistry/Immunofluorescence: ORP8 Antibody [NBP2-19634] - Immunofluorescence analysis of methanol-fixed HeLa, using antibody at 1:500 dilution. Western Blot: ORP8 Antibody [NBP2-19634] - Sample (30 ug of whole cell lysate) A: U87-MG 7. 5% SDS PAGE gel, diluted at 1:10000. 0.1 mL Connectez-vous pour afficher 8 to 11 Days
$447.56
Détails
Humain Souris Inconjugué WB OSBPL8 monoclonal antibody (M02), clone 4H6. Western Blot analysis of OSBPL8 expression in Jurkat. 0.1 mg Connectez-vous pour afficher 8 to 11 Days
$450.00
Détails
Humain Lapin Inconjugué ELISA, WB 50 μg Connectez-vous pour afficher 2 to 3 Days
$433.13
Détails
Humain Lapin Inconjugué ICC, IF, IHC, IHC (p) Immunohistochemistry-Paraffin: ORP8 Antibody [NBP1-92235] - Staining of human testis shows strong cytoplasmic positivity in cells in seminiferus ducts. Immunocytochemistry/Immunofluorescence: ORP8 Antibody [NBP1-92235] - Staining of human cell line A-431 shows positivity in nucleus but not nucleoli, cytoplasm & vesicles. 0.1 mL Connectez-vous pour afficher 10 to 13 Days
$439.69
Détails
Humain Lapin Inconjugué IHC, WB Western Blot: ORP8 Antibody [NBP1-59814] - Reccomended Titration: 0.2 - 1 ug/ml ELISA Titer: 1:1562500 Positive Control: 721_B cell lysate OSBPL8 is strongly supported by BioGPS gene expression data to be expressed in Human 721_B cells Western Blot: ORP8 Antibody [NBP1-59814] - 721_B cell lysate, concentration 0.2-1 ug/ml. 100 μL Connectez-vous pour afficher 8 to 11 Days
$447.56
Détails
Humain Lapin Inconjugué WB Western Blot: ORP8 Antibody [NBP1-59815] - HT1080, Antibody Dilution: 1.0 ug/ml OSBPL8 is strongly supported by BioGPS gene expression data to be expressed in Human HT1080 cells. Western Blot: ORP8 Antibody [NBP1-59815] - OVCAR-3 cell lysate, concentration 0.2-1 ug/ml. 100 μL Connectez-vous pour afficher 8 to 11 Days
$447.56
Détails

OSBPL8 Anticorps par réactivité, application, clonalité et conjugué

Attributs Application Hôte Clonalité
Rat (Rattus)


Human ,
,
,
Mouse (Murine)


Plus d’anticorps contre Oxysterol Binding Protein-Like 8 partenaires d’interaction

Human Oxysterol Binding Protein-Like 8 (OSBPL8) interaction partners

  1. we found that overexpression of ORP8 significantly inhibits GC cell proliferation and implanted tumor growth in vivo. Induction of ER stress, inhibition of Wnt (Montrer WNT2 Anticorps) signaling, and apoptotic cell death are involved in ORP8-induced inhibition of GC cell proliferation.

  2. mammalian ORP5 (Montrer OSBPL5 Anticorps) and ORP8 proteins localize to ER-mitochondrial MCS (Montrer SMCP Anticorps), in addition to ER-PM contact sites.

  3. the present study suggests that ORP8 may mediate the cytotoxicity of 25-hydroxycholesterol.

  4. ORP5 (Montrer OSBPL5 Anticorps) and ORP8 could mediate PI4P/phosphatidylserine (PS) countertransport between the endoplasmic reticulum (ER) and the plasma membrane (PM), thus delivering PI4P to the ER-localized PI4P phosphatase Sac1 (Montrer SACM1L Anticorps) for degradation and PS from the ER to the PM.

  5. role of ORP8 in Fas (Montrer FAS Anticorps) translocation to the plasma membrane and its down-regulation by miR (Montrer MLXIP Anticorps)-143 offer a putative mechanistic explanation for HCC (Montrer FAM126A Anticorps) resistance to apoptosis

  6. Data indicate that miR (Montrer MLXIP Anticorps)-143 impairs insulin (Montrer INS Anticorps) action via downregulation of oxysterol-binding protein-related protein 8 (ORP8).

  7. ORP8 overexpression resulted in reduced expression of the aP2 (Montrer GTF3A Anticorps) mRNA, while down-regulation of adiponectin (Montrer ADIPOQ Anticorps) and aP2 (Montrer GTF3A Anticorps) was observed in ORP11 (Montrer OSBPL11 Anticorps) silenced cells. ORP8 overexpression or silencing of ORP11 (Montrer OSBPL11 Anticorps) markedly decreased cellular triglyceride storage.

  8. results reveal that ORP8 has the capacity to modulate lipid homeostasis and SREBP activity, probably through an indirect mechanism, and provide clues of an entirely new mode of ORP action

  9. Data identify ORP8 as a negative regulator of ABCA1 (Montrer ABCA1 Anticorps) expression and macrophage cholesterol efflux. ORP8 may, thus, modulate the development of atherosclerosis.

Mouse (Murine) Oxysterol Binding Protein-Like 8 (OSBPL8) interaction partners

  1. Orp8 deficiency in bone marrow-derived cells reduces atherosclerotic lesion progression in LDL receptor (Montrer LDLR Anticorps) knockout mice.

  2. Osbpl8 deficiency in mouse causes an elevation of high-density lipoproteins and gender-specific alterations of lipid metabolism.

  3. aspects of ORP8 function in macrophages not directly involving lipid metabolism, but rather associated with nuclear functions, microtubule organization, and migration capacity

Oxysterol Binding Protein-Like 8 (OSBPL8) profil antigène

Profil protéine

This gene encodes a member of the oxysterol-binding protein (OSBP) family, a group of intracellular lipid receptors. Like most members, the encoded protein contains an N-terminal pleckstrin homology domain and a highly conserved C-terminal OSBP-like sterol-binding domain. Two transcript variants encoding different isoforms have been found for this gene.

Gene names and symbols associated with OSBPL8

  • oxysterol binding protein-like 8 (Osbpl8) anticorps
  • oxysterol binding protein like 8 (OSBPL8) anticorps
  • oxysterol binding protein like 8 L homeolog (osbpl8.L) anticorps
  • oxysterol binding protein like 8 (osbpl8) anticorps
  • oxysterol-binding protein-related protein 8 (LOC100175952) anticorps
  • AA536976 anticorps
  • AA536995 anticorps
  • C730029P18Rik anticorps
  • D330025H14Rik anticorps
  • DKFZp469P0923 anticorps
  • MST120 anticorps
  • MSTP120 anticorps
  • ORP-8 anticorps
  • ORP8 anticorps
  • OSBP10 anticorps
  • RGD1561474 anticorps

Protein level used designations for OSBPL8

oxysterol-binding protein-related protein 8 , oxysterol binding protein-like 8 , oxysterol-binding protein-like protein 8 , oxysterol-binding protein-related protein 8-like , ORP-8 , OSBP-related protein 8

GENE ID SPECIES
314824 Rattus norvegicus
417866 Gallus gallus
446929 Xenopus laevis
452085 Pan troglodytes
693338 Macaca mulatta
100018363 Monodelphis domestica
100059086 Equus caballus
100145444 Xenopus (Silurana) tropicalis
100172591 Pongo abelii
100175952 Ciona intestinalis
100218984 Taeniopygia guttata
100356792 Oryctolagus cuniculus
100484438 Ailuropoda melanoleuca
100525288 Sus scrofa
100566303 Anolis carolinensis
100595122 Nomascus leucogenys
100409878 Callithrix jacchus
114882 Homo sapiens
475408 Canis lupus familiaris
533350 Bos taurus
237542 Mus musculus
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