Perilipin 3 Protéines (PLIN3)

Mannose 6-phophate receptors (MPRs) deliver lysosomal hydrolase from the Golgi to endosomes and then return to the Golgi complex. De plus, nous expédions Perilipin 3 Anticorps (214) et Perilipin 3 Kits (6) et beaucoup plus de produits pour cette protéine.

afficher tous les protéines Gène GeneID UniProt
PLIN3 66905 Q9DBG5
PLIN3 10226 O60664
Rat PLIN3 PLIN3 316130  
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Showing 7 out of 7 products:

Catalogue No. Origin Source Conjugué Images Quantité Fournisseur Livraison Prix Détails
Escherichia coli (E. coli) Humain His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Connectez-vous pour afficher 30 to 35 Days
$5,370.21
Détails
Escherichia coli (E. coli) Souris His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Connectez-vous pour afficher 30 to 35 Days
$5,370.21
Détails
HEK-293 Cells Humain Myc-DYKDDDDK Tag Validation with Western Blot 20 μg Connectez-vous pour afficher 11 Days
$888.80
Détails
Wheat germ Humain GST tag 10 μg Connectez-vous pour afficher 11 to 12 Days
$414.29
Détails
Levure Orang-Utan His tag   1 mg Connectez-vous pour afficher 60 to 71 Days
$3,210.17
Détails
Levure Sanglier His tag   1 mg Connectez-vous pour afficher 60 to 71 Days
$3,224.83
Détails
Escherichia coli (E. coli) Humain Inconjugué   100 μg Connectez-vous pour afficher 11 to 18 Days
$582.75
Détails

PLIN3 Protéines protéines par origine et source

Origin Exprimée danse Conjugué
Mouse (Murine)

Human , ,
, ,

Plus protéines pour Perilipin 3 (PLIN3) partenaires d'interaction

Mouse (Murine) Perilipin 3 (PLIN3) interaction partners

  1. These data suggest that Plin3 acts as an intrinsic protective factor preventing futile beige adipocyte formation by limiting lipid metabolism and thermogenic gene expression.

  2. our studies demonstrate that the lipid droplets (LDs) scaffold protein, PLIN3, is essential for HCV core-induced hepatic steatosis and provide new insights into the pathogenesis of HCV.

  3. Postprandial triglyceride rich lipoproteins may be involved in atherosclerotic plaque formation through the regulation of perilipin-2 and perilipin-3 proteins in macrophages.

  4. Collectively these data suggest that whereas perilipin 1 potently suppresses basal lipolysis in adipocytes, perilipins 2 and 3 facilitate higher rates of basal lipolysis

  5. Data indicate that PLIN2 and PLIN3 may participate in acute lipid droplet formation in mammalian testes.

  6. These findings show that TIP47 affects hepatic lipid and glucose metabolism and may be a target for the treatment of nonalcoholic fatty liver and related metabolic disorders.

  7. Overexpression of tail interacting protein of 47 kDa (TIP47), but not its truncated form (t-TIP47) protected NIH3T3 cells from hydrogen-peroxide-induced cell death, prevented the hydrogen-peroxide-induced mitochondrial depolarization.

  8. the non-lipid droplet pools of S3-12, adipophilin, and TIP47 constitute a ready reservoir of coat proteins to permit rapid packaging of newly synthesized triacylglycerol and to maximize energy storage during nutrient excess

  9. Adipophilin and TIP47 are expressed in LDs of vitamin A-storing hepatic stellate cells and additionally in lipid droplets of steatotic hepatocytes.

  10. Data establish an important role for Tip47 proteins as surfactant at the LD surface, packaging lipids in smaller units and restricting access of lipases and thus preventing insulin resistance.

  11. These results suggest distinct roles for TIP47 and adipophilin in dietary fat absorption.

  12. Membrane-permeable diacylglycerols drive Perilipin 3 onto the endoplasmic reticulum.

Human Perilipin 3 (PLIN3) interaction partners

  1. High PLIN3 expression is associated with clear cell renal cell carcinoma.

  2. we found a DPP9-PPP6R3 fusion transcript in one tumor showing a matching genomic 11;19-translocation. Another tumor had a rearrangement of DPP9 with PLIN3. Both rearrangements were associated with diminished expression of the 3' end of DPP9 corresponding to the breakpoints identified by RNA-seq.

  3. Conserved amphipathic helices mediate lipid droplet targeting of PLIN1, PLIN2, and PLIN3.

  4. PLIN3 functions are intertwined with the lipogenic pathways implicated in sebaceous lipogenesis, such as desaturation and triglyceride synthesis.

  5. Postprandial triglyceride rich lipoproteins may be involved in atherosclerotic plaque formation through the regulation of perilipin-2 and perilipin-3 proteins in macrophages.

  6. Differential expression of PLIN3 and brefeldin A sensitivity may explain differential lipid oxidation efficiency in skeletal muscle among healthy lean, sedentary, and T2 diabetic males.

  7. Results indicate that microRNAs miR-148a and miR-30a, regulate Tail interacting protein of 47 kDa (TIP47) expression and lipid droplets (LD) in hepatitis C virus infected cells.

  8. Following exercise training, perilipin 3 protein expression was increased in the adipose tissue of women with polycystic ovary syndrome.

  9. Skeletal muscle perilipin 3 and coatomer proteins are increased following exercise and are associated with fat oxidation.

  10. Rab9-complexed TIP47 plays an essential role for the proper release of hepatitis C viral particles.

  11. PLIN3 is associated with the synthesis and secretion of PGE2

  12. TIP47 plays an essential role in the life cycle of hepatitis C virus.

  13. studies identified the lipid droplet(LD-associated host protein, Tail-Interacting Protein 47 (TIP47) as a novel NS5A interaction partner; data support a model where TIP47-via its interaction with NS5A-serves as a novel cofactor for HCV infection possibly by integrating LD membranes into the membranous web

  14. TIP47 is here described for the first time as a viral restriction factor that acts by limiting viral protein synthesis.

  15. PLIN2-PLIN5 proteins were all more abundant in women than in men (p = 0.037 and p < 0.0001, respectively), consistent with higher intramyocellular lipid content in female skeletal muscle.

  16. Suppression of TIP47 in HeLa cells facilitated oxidative-stress-induced cell death.

  17. TIP47 is required for the encounter between Gag and Env, and thus for the generation of infectious HIV-1 particles from primary macrophages.

  18. can co-localize with lipid storage proteins

  19. Data show that placental protein 17b (PP17b)is a neutral lipid droplet-associated protein, and its expression is regulated by PKC- and PKA-dependent pathways

  20. TIP47 binding to HIV-1 envelope glycoprotein (ENV) is required for ENV transport to the trans-golgi network and for its incorportaion into virions and its pathogenicity

Pig (Porcine) Perilipin 3 (PLIN3) interaction partners

  1. PLIN3 expression in cumulus cells and oocytes during in vitro maturation.

  2. This work describes the cloning and sequencing of porcine PLIN and M6PRBP1 cDNAs, the chromosome mapping of these two genes, as well as the expression pattern of porcine PAT genes.

Cow (Bovine) Perilipin 3 (PLIN3) interaction partners

  1. Adipophilin and TIP47 are expressed in lipid droplets of vitamin A-storing hepatic stellate cells and additionally in lipid droplets of steatotic hepatocytes.

Profil protéine Perilipin 3 (PLIN3)

Profil protéine

Mannose 6-phophate receptors (MPRs) deliver lysosomal hydrolase from the Golgi to endosomes and then return to the Golgi complex. The protein encoded by this gene interacts with the cytoplasmic domains of both cation-independent and cation-dependent MPRs, and is required for endosome-to-Golgi transport. This protein also binds directly to the GTPase RAB9 (RAB9A), a member of the RAS oncogene family. The interaction with RAB9 has been shown to increase the affinity of this protein for its cargo. Multiple transcript variants encoding different isoforms have been found for this gene.

Gene names and symbols associated with Perilipin 3 Protéines (PLIN3)

  • perilipin 3 (Plin3)
  • perilipin 3 (PLIN3)
  • si:rp71-61h23.4 (si:rp71-61h23.4)
  • perilipin 3 S homeolog (plin3.S)
  • perilipin 3 L homeolog (plin3.L)
  • 1300012C15Rik Protéine
  • fl05f04 Protéine
  • m6prbp1 Protéine
  • MGC53750 Protéine
  • MGC80328 Protéine
  • PLIN3 Protéine
  • pp17 Protéine
  • tip47 Protéine
  • wu:fl05f04 Protéine

Protein level used designations for Perilipin 3 Protéines (PLIN3)

cargo selection protein TIP47 , mannose-6-phosphate receptor binding protein 1 , mannose-6-phosphate receptor-binding protein 1 , perilipin-3 , 47 kDa MPR-binding protein , placental protein 17 , tail-interacting protein, 47 kD , perilipin 3 , 47 kDa tail interaction protein , TIP47 , mannose 6 phosphate receptor binding protein 1 , Mannose-6-phosphate receptor-binding protein 1

GENE ID SPECIES
66905 Mus musculus
10226 Homo sapiens
316130 Rattus norvegicus
335278 Danio rerio
446543 Xenopus laevis
455612 Pan troglodytes
485031 Canis lupus familiaris
595103 Sus scrofa
767984 Bos taurus
100172561 Pongo abelii
379347 Xenopus laevis
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