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The protein encoded by PRDX4 is an antioxidant enzyme and belongs to the peroxiredoxin family. De plus, nous expédions Peroxiredoxin 4 Anticorps (106) et Peroxiredoxin 4 Protéines (23) et beaucoup plus de produits pour cette protéine.
Showing 4 out of 25 products:
Human Peroxiredoxin 4 Kit ELISA pour Sandwich ELISA - ABIN454367
Al-Masri, El Eter, Tayel, Zamil: Differential associations of circulating peroxiredoxins levels with indicators of glycemic control in type 2 diabetes mellitus. dans European review for medical and pharmacological sciences 2014
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Human Peroxiredoxin 4 Kit ELISA pour Sandwich ELISA - ABIN2685264
Guo, Yamada, Tanimoto, Ding, Wang, Shimajiri, Murata, Kimura, Tasaki, Nabeshima, Watanabe, Kohno, Sasaguri: Overexpression of peroxiredoxin 4 attenuates atherosclerosis in apolipoprotein E knockout mice. dans Antioxidants & redox signaling 2012
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Human Peroxiredoxin 4 Kit ELISA pour Sandwich ELISA - ABIN421343
Choi, Cho, Seo, Park, Kim, Lee: Alteration of the intrafollicular thiol-redox system in infertile women with endometriosis. dans Reproduction (Cambridge, England) 2014
levels of peroxiredoxin 4 are higher in patients with prediabetes, but are similar in subjects with and without insulin (Montrer INS Kits ELISA) resistance, which suggests that the main factor for its increased levels is hyperglycaemia and not insulin (Montrer INS Kits ELISA) sensitivity state.
Results show that ERp44 (Montrer ERP44 Kits ELISA) binds the oxidized but not the reduced form of Prx4; the ERp44 (Montrer ERP44 Kits ELISA)-Prx4 complex is formed via thiol-disulfide interchange reactions, and its crystal structure reveals a redox-dependent recognition.
Prdx4 expression was closely related to follicular development and has aprominent role in protecting human and mouse granulosa cells from reactive oxygen species damage.
Positive Prx 4 expression is significantly correlated with recurrence and shorter disease-free survival in patients with early-stage lung squamous cell carcinoma.
An off-pathway reaction in the Prx4-mediated oxidative protein folding.
Findings suggest that elevated serum Prx4 levels are associated with a higher risk of incident type 2 diabetes
Prx4 is a circulating antioxidant and is independently associated with increased risk of cardiovascular and all-cause mortality in T2DM.
these data suggest an important role of Prdx4 in maintaining insulin (Montrer INS Kits ELISA) levels and improving the ER folding capacity also under conditions of a high insulin (Montrer INS Kits ELISA) requirement.
there is a significant difference in concentration of Prx4 between cardiac arrest patients with good and poor outcome
The structure and function of PRDX4 as well as its sensitivity to hyperoxidation. [Review]
data provide the first evidence of the beneficial effects of PRDX4 on intestinal function in the reduction of the severity of NAFLD (Montrer TSC2 Kits ELISA), by ameliorating oxidative stress-induced (Montrer SQSTM1 Kits ELISA) local and systemic injury
The ventral signal observed for Prdx4 from early stages colocalized with motor neuron markers Isl1 (Montrer ISL1 Kits ELISA)/2 and FoxP1 (Montrer FOXP1 Kits ELISA) and the strong ventral signal colocalizing with Isl1 (Montrer ISL1 Kits ELISA)/2 was observed in all rostrocaudal segments of the spinal cord.
Prdx4 dimers generated by hydrogen peroxide metabolism oxidize two cysteine residues within the GDE2 enzymatic domain, which blocks GDE2 trafficking to the plasma membrane and prevents GDE2 neurogeneic function.
PRDX4 may protect against nonalcoholic steatohepatitis and type 2 diabetes by ameliorating oxidative stress-induced (Montrer SQSTM1 Kits ELISA) injury.
data suggest that PRDX4 can be a novel target for glioblastoma multiforme therapies in the future
combined loss-of-function mutations in genes encoding the ER thiol oxidases ERO1alpha, ERO1beta, and PRDX4 compromised the extracellular matrix and interfered with the intracellular maturation of procollagen
Prx IV-L functions as an H(2)O(2) sensor that mediates protein thiol oxidation required for the maturation of spermatozoa in placental mammals.
The results indicate that spermatogenic cells lacking Prx4 are more susceptible to cell death via oxidative damage than their wild-type counterparts.
The protein encoded by this gene is an antioxidant enzyme and belongs to the peroxiredoxin family. The protein is localized to the cytoplasm. Peroxidases of the peroxiredoxin family reduce hydrogen peroxide and alkyl hydroperoxides to water and alcohol with the use of reducing equivalents derived from thiol-containing donor molecules. This protein has been found to play a regulatory role in the activation of the transcription factor NF-kappaB.
, thioredoxin peroxidase
, antioxidant enzyme AOE372
, peroxiredoxin IV
, thioredoxin peroxidase (antioxidant enzyme)
, thioredoxin peroxidase AO372
, thioredoxin-dependent peroxide reductase A0372
, Prx IV