anti-Phosphoglycerate Mutase Family Member 5 (PGAM5) Anticorps

Displays phosphatase activity for serine/threonine residues, and, dephosphorylates and activates MAP3K5 kinase. De plus, nous expédions PGAM5 Kits (9) et PGAM5 Protéines (7) et beaucoup plus de produits pour cette protéine.

afficher tous les anticorps Gène GeneID UniProt
PGAM5 192111 Q96HS1
PGAM5 72542 Q8BX10
PGAM5 288731 Q562B5
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Top anti-PGAM5 Anticorps sur anticorps-enligne.fr

Showing 10 out of 10 products:

Catalogue No. Reactivité Hôte Conjugué Application Images Quantité Fournisseur Livraison Prix Détails
Humain Lapin Inconjugué ICC, IF, IHC, IHC (p), SimWes, WB Simple Western: PGAM5 Antibody [NBP1-92257] - Electropherogram image(s) of corresponding Simple Western lane view. PGAM5 antibody was used at 1:60 dilution on RT-4 lysate(s). Immunohistochemistry-Paraffin: PGAM5 Antibody [NBP1-92257] - Staining of human uterus, pre-menopause shows strong cytoplasmic positivity in glandular cells. 0.1 mL Connectez-vous pour afficher 10 to 13 Days
$494.38
Détails
Humain Lapin Inconjugué IHC, IHC (p), WB Western Blot: PGAM5 Antibody [NBP1-92258] - Lane 1: Marker [kDa] 230, 130, 95, 72, 56, 36, 28, 17, 11.Lane 2: Human cell line RT-4 Western Blot: PGAM5 Antibody [NBP1-92258] - Lane 1: NIH-3T3 cell lysate (Mouse embryonic fibroblast cells).Lane 2: NBT-II cell lysate (Rat Wistar bladder tumour cells) 0.1 mL Connectez-vous pour afficher 10 to 13 Days
$494.38
Détails
Humain Souris Inconjugué IHC, IHC (p), WB Western Blot: PGAM5 Antibody (CL0624)  - Analysis in RT-4 cells transfected with control siRNA, target specific siRNA probe #1 and #2, using Anti-PGAM5 antibody. Remaining relative intensity is presented. Loading control: Anti-PARP1. Western Blot: PGAM5 Antibody (CL0624)  - Lane 1: Marker  Lane 2: Human cell line RT-4 0.1 mL Connectez-vous pour afficher 10 to 13 Days
$494.38
Détails
Humain Lapin Inconjugué IHC (p), WB Immunohistochemical staining of human pancreas with PGAM5 polyclonal antibody  shows strong cytoplasmic positivity in granular pattern in exocrine pancreas. Western blot analysis of Lane 1: RT-4, Lane 2: U-251 MG, Lane 3: Human Plasma, Lane 4: Liver, Lane 5: Tonsil with PGAM5 polyclonal antibody . 100 μL Connectez-vous pour afficher 11 to 12 Days
$452.00
Détails
Humain Lapin Inconjugué IF, IHC (p), WB Immunohistochemical staining of human uterus, pre-menopause with PGAM5 polyclonal antibody  shows strong cytoplasmic positivity in glandular cells at 1:200-1:500 dilution. Western blot analysis of Lane 1: RT-4, Lane 2: U-251 MG, Lane 3: Human Plasma, Lane 4: Liver, Lane 5: Tonsil with PGAM5 polyclonal antibody  at 1:500-1:1000 dilution. 100 μL Connectez-vous pour afficher 11 to 12 Days
$452.00
Détails
Humain Souris Inconjugué IHC (p), WB Western Blot analysis of RT-4 cell lysate with PGAM5 monoclonal antibody, clone CL0624 . Immunohistochemical staining (Formalin-fixed paraffin-embedded sections) of human kidney with PGAM5 monoclonal antibody, clone CL0624  shows either strong or moderate cytoplasmic immunoreactivity in subsets of renal tubules. 100 μL Connectez-vous pour afficher 11 to 12 Days
$637.32
Détails
Humain Lapin HRP ELISA   100 μg Connectez-vous pour afficher 11 to 18 Days
$412.19
Détails
Humain Lapin Biotin ELISA   100 μg Connectez-vous pour afficher 11 to 18 Days
$412.19
Détails
Humain Lapin FITC ELISA   100 μg Connectez-vous pour afficher 11 to 18 Days
$412.19
Détails
Humain Lapin Inconjugué ELISA, IF/ICC, IHC   100 μg Connectez-vous pour afficher 11 to 18 Days
$412.19
Détails

Plus d’anticorps contre PGAM5 partenaires d’interaction

Fruit Fly (Drosophila melanogaster) Phosphoglycerate Mutase Family Member 5 (PGAM5) interaction partners

  1. The authors show that developmental mitochondrial unfolded protein response is necessary and sufficient to extend Drosophila lifespan, and identify Phosphoglycerate Mutase 5 (PGAM5) as a mediator of this response. Developmental mitochondrial stress leads to activation of FoxO, via Apoptosis Signal-regulating Kinase 1 (ASK1) and Jun-N-terminal Kinase (JNK).

  2. the mushroom body may possess an apoptosis-dependent toxic function, the suppression of which by dPGAM5 appears to be crucial for heat shock resistance.

  3. PGAM5 negatively regulates the PINK1 pathway related to maintenance of the mitochondria.

Human Phosphoglycerate Mutase Family Member 5 (PGAM5) interaction partners

  1. suggests that PGAM5 senses mitochondrial dysfunction in the inner mitochondrial membrane and serves as a signalling intermediate that regulates the cellular response to mitochondrial stress upon its cleavage and release from mitochondria

  2. An intact complex of PGAM5-KEAP1-Nrf2 preserves mitochondrial motility by suppressing dominant-negative KEAP1 activity.

  3. PGAM5 regulates histidine phosphorylation to control TCR activation of CD4-positive T cells.

  4. Results indicate that a multiprotein complex including PGAM5, Bax and Drp1 proteins specifically formed during intrinsic apoptosis induction.

  5. Results identify a crucial role for RIPK3-PGAM5-Drp1/NFAT signalling in NKT cell activation, and further suggest that RIPK3-PGAM5 signalling may mediate crosstalk between mitochondrial function and immune signalling.

  6. The BCL2L1-PGAM5-FUNDC1 axis is critical for receptor-mediated mitophagy.

  7. Dephosphorylation of FUNDC1 by PGAM5 induces mitophagy.

  8. PGAM5 is proteolytically processed, accumulates in the cytosol during apoptosis, and sensitizes cells to death.

  9. Rhomboid protease PARL mediates the mitochondrial membrane potential loss-induced cleavage of PGAM5.

  10. Experimental data indicate that the two splice variants of the mitochondrial protein phosphatase PGAM5 are at the convergent point of multiple necrosis pathways.

  11. The N terminus of the PGAM5 protein contains a conserved NXESGE motif that binds to the substrate binding pocket in the Kelch domain of Keap1.

  12. Results suggest that this member of the PGAM family has crossed over from small molecules to protein substrates and been adapted to serve as a specialized activator of ASK1.

Mouse (Murine) Phosphoglycerate Mutase Family Member 5 (PGAM5) interaction partners

  1. melatonin treatment inhibited the Ripk3-PGAM5-CypD-mPTP cascade and thus reduced cellular necroptosis, conferring a protective advantage to the endothelial system in IR stress.

  2. findings suggest that HO-1 protects against I/R-induced hepatic injury via regulation of mitochondrial QC by PGAM5 signaling.

  3. Taken together, our findings provide evidence that NBP can attenuate the progression of EAE by suppressing PGAM5-induced necroptosis and inflammation in microglia and represents a new therapeutic strategy for treating autoimmune diseases.

  4. PGAM5 regulates histidine phosphorylation to control TCR activation of CD4-positive T cells.

  5. Results revealed that RIPK1 and PGAM5 function independently to exert optimal control of Leishmania replication in the host.

  6. Our data demonstrate for the first time that PGAM5 plays an indispensable role in the pathogenesis of ConA-induced liver injury.

  7. we also found that Pgam5-deficient mice are resistant to high-fat-diet-induced obesity. Our study uncovered that PGAM5 is involved in the whole-body metabolism in response to stresses that impose metabolic challenges on mitochondria.

  8. Our results revise the former proposal that PGAM5 acts downstream of RIP1/RIP3 to mediate necroptosis. Instead, PGAM5 protects cells from necroptosis by independently promoting mitophagy.

  9. PGAM5 is a novel regulator of inflammasome and caspase 1 activity that functions independently of RIPK3.

  10. Results identify a crucial role for RIPK3-PGAM5-Drp1/NFAT signalling in NKT cell activation, and further suggest that RIPK3-PGAM5 signalling may mediate crosstalk between mitochondrial function and immune signalling.

  11. Loss of PGAM5 disables PINK1-mediated mitophagy in vitro and leads to dopaminergic neurodegeneration and mild dopamine loss in vivo causing a Parkinson's-like movement disorder.

  12. Data indicate that phosphoglycerate mutase 5 (PGAM5) contains an N-terminal WDXNWD motif required for multimerization and maximal phosphatase activity.

  13. Experimental data indicate that the two splice variants of the mitochondrial protein phosphatase PGAM5 are at the convergent point of multiple necrosis pathways.

Xenopus laevis Phosphoglycerate Mutase Family Member 5 (PGAM5) interaction partners

  1. Pgam5 is essential for head formation, and for establishing and maintaining the Wnt/beta-Catenin signaling gradient that patterns the anterior-posterior body axis. We show that Pgam5 interacts with Dishevelled2 and that Dishevelled2 is a substrate of Pgam5.

PGAM5 profil antigène

Profil protéine

Displays phosphatase activity for serine/threonine residues, and, dephosphorylates and activates MAP3K5 kinase. Has apparently no phosphoglycerate mutase activity. May be regulator of mitochondrial dynamics. Substrate for a KEAP1-dependent ubiquitin ligase complex. Contributes to the repression of NFE2L2- dependent gene expression (By similarity).

Gene names and symbols associated with PGAM5

  • Phosphoglycerate mutase 5 (Pgam5) anticorps
  • PGAM family member 5, mitochondrial serine/threonine protein phosphatase (PGAM5) anticorps
  • phosphoglycerate mutase family member 5 (Pgam5) anticorps
  • PGAM family member 5, mitochondrial serine/threonine protein phosphatase (Pgam5) anticorps
  • PGAM family member 5, serine/threonine protein phosphatase, mitochondrial S homeolog (pgam5.S) anticorps
  • PGAM family member 5, serine/threonine protein phosphatase, mitochondrial (pgam5) anticorps
  • 2610528A17Rik anticorps
  • BXLBV68 anticorps
  • CG14816 anticorps
  • Dmel\\CG14816 anticorps
  • dPGAM5 anticorps
  • EG:63B12.4 anticorps
  • PGAM5 anticorps
  • RGD1312028 anticorps
  • si:dkey-69p22.1 anticorps
  • wu:fb39f09 anticorps
  • wu:fj34f06 anticorps
  • zgc:92057 anticorps
  • zgc:112041 anticorps

Protein level used designations for PGAM5

CG14816-PA , Pgam5-PA , phosphoglycerate mutase 5 , Bcl-XL-binding protein v68 , serine/threonine-protein phosphatase PGAM5, mitochondrial , fb39f09

GENE ID SPECIES
31143 Drosophila melanogaster
192111 Homo sapiens
72542 Mus musculus
288731 Rattus norvegicus
398484 Xenopus laevis
492357 Danio rerio
Fournisseurs de qualité sélectionnés pour anti-PGAM5 (PGAM5) Anticorps
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