anti-Shugoshin-Like 2 (S. Pombe) Anticorps

Profil protéine

Cooperates with PPP2CA to protect centromeric cohesin from separase-mediated cleavage in oocytes specifically during meiosis I. Has a crucial role in protecting REC8 at centromeres from cleavage by separase. During meiosis, protects centromeric cohesion complexes until metaphase II/anaphase II transition, preventing premature release of meiosis-specific REC8 cohesin complexes from anaphase I centromeres. Is thus essential for an accurate gametogenesis. May act by targeting PPP2CA to centromeres, thus leading to cohesin dephosphorylation (By similarity). Essential for recruiting KIF2C to the inner centromere and for correcting defective kinetochore attachments.

Gene names and symbols associated with SGOL2

• shugoshin 2 (SGO2) anticorps
• shugoshin 2A (Sgo2a) anticorps

• 1110007N04Rik anticorps
• 4932411A20Rik anticorps
• 5730576N04Rik anticorps
• AU018846 anticorps
• AV008062 anticorps
• Afficher tous les alias de synonymes
• D1Ertd8e anticorps
• SGO2 anticorps
• Tripin anticorps

Protein level used designations for SGOL2

shugoshin-2 , shugoshin-like 2 , sgo2