Sodium Channel, Nonvoltage-Gated 1, gamma (SCNN1G) Kits ELISA

Nonvoltage-gated, amiloride-sensitive, sodium channels control fluid and electrolyte transport across epithelia in many organs. De plus, nous expédions Sodium Channel, Nonvoltage-Gated 1, gamma Anticorps (130) et Sodium Channel, Nonvoltage-Gated 1, gamma Protéines (7) et beaucoup plus de produits pour cette protéine.

list all ELISA KIts Gène GeneID UniProt
SCNN1G 6340 P51170
Anti-Souris SCNN1G SCNN1G 20278 Q9WU39
Anti-Rat SCNN1G SCNN1G 24768 P37091
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Top Sodium Channel, Nonvoltage-Gated 1, gamma Kits ELISA sur anticorps-enligne.fr

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Catalogue No. Reactivité Sensibilité Gamme Images Quantité Livraison Prix Détails
Humain 0.113 ng/mL 0.31 ng/mL - 20 ng/mL 96 Tests 13 to 16 Days
$736.84
Détails

Plus Kits ELISA pour Sodium Channel, Nonvoltage-Gated 1, gamma partenaires d'interaction

Xenopus laevis Sodium Channel, Nonvoltage-Gated 1, gamma (SCNN1G) interaction partners

  1. Plasmin in nephrotic urine activates the epithelial sodium channel

Human Sodium Channel, Nonvoltage-Gated 1, gamma (SCNN1G) interaction partners

  1. SCNN1G was not associated with Salt Sensitivity of Blood Pressure in rare variant analyses.

  2. Albuminuria in kidney transplant recipients is associated with hypertension, ability of urine to proteolytically activate ENaC current, and increased abundance of gammaENaC.

  3. Proteolytic cleavage activates epithelial sodium channel (SCNN) by removal of specific segments in finger domains of alpha and gamma subunits. Data suggest that the lower "palm" domain of SCNN1A is essential for allosteric activation of the SCNN heterotetramer [SCNN1A(1)-SCNN1B-SCNN1A(2)-SCNN1G].

  4. In the present study, the SCNN1G gene was associated with 24-h urinary sodium excretion but was not related to blood pressure. The SCNN1A and SCNN1B genes were not associated with blood pressure either.

  5. The derlin-1 pathway therefore may represent a significant early checkpoint in the recognition and degradation of ENaC in mammalian cells.

  6. hENaC incorporating the Liddle-mutated beta-subunit lacks one or more PKC phosphorylation sites, thereby significantly reducing the inhibitory effect of PKC on Na(+) channel activity, whereas hENaC incorporating Liddle-mutated gamma-subunits remains as susceptible to PKC as wild-type hENaC.

  7. deltabetagamma-ENaC is inhibited by CFTR but activated by cyclic AMP.

  8. One nonsynonymous amino acid variants in SCNN1G in nonwhite Cystic fibrosis patients with non-diagnostic CFTR genotypes was identified.

  9. Both vascular smooth muscle cell and bronchial gamma-ENaC downregulation may explain pulmonary fluid disturbances and participate in pulmonary edema pathogenesis.

  10. The transcriptional expression of alpha, beta, and gamma subunits of ENaC was elevated in nasal polyp compared to nasal mucosa

  11. Suggest that SCNN1G gene has important roles in blood pressure regulation in the Han Chinese population.

  12. SCNN1A and SCNN1G SNPs may contribute to blood pressure changes over time in the Han Chinese population.

  13. Data indicate that urokinase-type plasminogen activator (uPA) activates epithelial sodium channel, gamma subunit (ENaC gamma) through catalytic activity-dependent proteolytic modification.

  14. High serum leptin may reduce endometrial receptivity by activating the STAT3 signal pathway and down-regulating gamma-ENaC expression in the endometrium.

  15. human kidney gammaENaC is subject to proteolytic cleavage, yielding fragments compatible with furin cleavage, and proteinuria is associated with cleavage at the putative prostasin/kallikrein site and removal of the inhibitory tract within gammaENaC

  16. gamma subunit palmitoylation has a dominant role over beta subunit palmitoylation in modulating ENaC gating

  17. WNK4 inhibits ENaC channel activity independently of Nedd4-2-mediated ENaC ubiquitination.

  18. found a diminished expression of the three subunits of the ENaC in the membranes of preeclamptic placentas in comparison with the normal ones

  19. These results suggest that the mutant gammaL511Q enhances ENaC activity by increasing channel open probability and dampens channel regulation by extracellular Na(+) and proteases.

  20. analysis of eight extracellular domain residues in human beta- and gammaENaC that are required for regulation by acidic pH

Mouse (Murine) Sodium Channel, Nonvoltage-Gated 1, gamma (SCNN1G) interaction partners

  1. Apical fluid shear stress specifically downregulates beta-ENaC and gamma-ENaC subunits at the transcriptional level through an unidentified heat-insensitive paracrine basolateral factor in collecting duct principal cells.

  2. the results of the present study demonstrated that insulin protected the lung epithelium and attenuated pulmonary edema through the upregulation of ENaC via the PI3K/SGK1 pathway in LPSinduced lung injury.

  3. Casein kinase 2 phosphorylation is an important regulator of ENaC activity and sodium handling by the aldosterone sensitive distal nephron.

  4. N-linked glycans on each subunit are required for proper folding, maturation, surface expression, and function of the epithelial sodium channel.

  5. The derlin-1 pathway therefore may represent a significant early checkpoint in the recognition and degradation of ENaC in mammalian cells.

  6. ENaC and ROMK channel activity in kidney tubules are inhibited in TgWnk4(pseudoaldosteronism type II) mice. Wnk4(PHAII)-induced inhibition of ENaC and ROMK may contribute to the suppression of K(+) secretion in the tubules.

  7. Mouse cells conditionally overexpressing gamma ENAC had enhanced apical Na(+) entry increased the basolateral cell surface expression of Na,K-ATPase by inhibiting p38 kinase-mediated endocytosis of Na,K-ATPase.

  8. Data indicate that insulin receptor (InsR) is important for epithelial sodium channel (ENaC) activity.

  9. These data suggest that adenylyl cyclase VI mediates vasopressin-stimulated ENaC activity in the kidney.

  10. Cys substitutions at sites in the wrist domains of the beta and gamma subunits alter the Na+ self-inhibition response.

  11. ENaC is not a passive passenger in regulated epithelial vesicle trafficking, but plays a role in establishing and maintaining the pool of vesicles that respond to cAMP stimulation.

  12. The reactive intermediates formed during and after exposure to chlorine activated ERK1/2 in alveolar epithelial cells, leading to decreased ENaC concentrations and activity.

  13. TMPRSS4 primarily activates ENaC by cleaving basic residues within the tract gammaK173-K186 distal to the furin cleavage site, thereby releasing a previously defined key inhibitory tract encompassing gammaR158-F168 from the gamma-subunit.

  14. estrogen regulates expression and function of epithelial sodium channel gamma in osteoblasts

  15. Il-6 activates ENaC-gamma channels in cortical collecting duct cells.

  16. Dot1a and AF9 downregulate Na(+) transport, most likely by regulating ENaC mRNA and subsequent protein expression and ENaC activity.

  17. pore regions from the three ENaC subunits have an asymmetric organization

  18. Alpha-, beta-, or gamma-ENaC coimmunoprecipitated with myc-tagged alpha-alpha-M1H1 and its downstream hydrophilic extracellular loop. Alpha-subunit participates in subunit-subunit interactions required for assembly of heterooligomeric ENaC complex.

  19. ATP regulation of ENaC may be involved in the fine-tuning of ENaC activity under physiologic and pathophysiologic conditions

  20. residues within Gln573-Arg583 of gammaENaC are necessary for normal channel gating

Sodium Channel, Nonvoltage-Gated 1, gamma (SCNN1G) profil antigène

Antigen Summary

Nonvoltage-gated, amiloride-sensitive, sodium channels control fluid and electrolyte transport across epithelia in many organs. These channels are heteromeric complexes consisting of 3 subunits: alpha, beta, and gamma. This gene encodes the gamma subunit, and mutations in this gene have been associated with Liddle syndrome.

Gene names and symbols associated with SCNN1G

  • sodium channel epithelial 1 gamma subunit (SCNN1G) anticorps
  • sodium channel, nonvoltage-gated 1, gamma (scnn1g) anticorps
  • sodium channel, nonvoltage-gated 1 gamma (Scnn1g) anticorps
  • sodium channel epithelial 1 gamma subunit (Scnn1g) anticorps
  • BESC3 anticorps
  • ENaC anticorps
  • ENaCg anticorps
  • ENaCgamma anticorps
  • GAMMA-ENAC anticorps
  • MGC81424 anticorps
  • PHA1 anticorps
  • SCNEG anticorps
  • SCNN1G anticorps
  • [g]ENaC anticorps

Protein level used designations for SCNN1G

sodium channel, nonvoltage-gated 1, gamma , amiloride-sensitive sodium channel subunit gamma , epithelium sodium channel gamma subunit , amiloride sensitive epithelial sodium channel gamma subunit , ENaC gamma subunit , amiloride-sensitive epithelial sodium channel gamma subunit , amiloride-sensitive sodium channel gamma-subunit , epithelial Na(+) channel subunit gamma , gamma-ENaC , gamma-NaCH , nonvoltage-gated sodium channel 1 subunit gamma , SCNEG , amiloride-sensitive sodium channel gamma subunit , epithelial sodium channel ENaC gamma subunit , epithelial sodium channel, gamma subunit , ENaC gamma , Sodium channel nonvoltage-gated 1 gamma (epithelial) , Sodium channel, nonvoltage-gated 1, gamma (epithelial) , amiloride sensitive sodium channel gamma1 subunit , epithelial sodium channel gamma subunit , sodium channel, nonvoltage-gated, type I, gamma

GENE ID SPECIES
416579 Gallus gallus
467925 Pan troglodytes
489973 Canis lupus familiaris
617802 Bos taurus
699971 Macaca mulatta
779366 Xenopus laevis
100170326 Ovis aries
100460323 Pongo abelii
6340 Homo sapiens
100008850 Oryctolagus cuniculus
20278 Mus musculus
24768 Rattus norvegicus
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