anti-Src Kinase Associated Phosphoprotein 2 (SKAP2) Anticorps

The protein encoded by SKAP2 belongs to the src family kinases. De plus, nous expédions SKAP2 Protéines (12) et et beaucoup plus de produits pour cette protéine.

afficher tous les anticorps Gène GeneID UniProt
SKAP2 54353 Q3UND0
SKAP2 8935 O75563
SKAP2 155183 Q920G0
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Top anti-SKAP2 Anticorps sur anticorps-enligne.fr

Showing 10 out of 83 products:

Catalogue No. Reactivité Hôte Conjugué Application Images Quantité Livraison Prix Détails
Boeuf (Vache) Lapin Inconjugué WB Host: Rabbit Target Name: SKAP2 Sample Type: PANC1 Whole Cell lysates Antibody Dilution: 1.0ug/ml 100 μL 2 to 3 Days
$289.00
Détails
Humain Chèvre Inconjugué ELISA, WB ABIN184706 (0.5µg/ml) staining of Jurkat lysate (35µg protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence. 100 μg 6 to 7 Days
$429.84
Détails
Humain Lapin Inconjugué ICC, IF, IHC (p), WB ICC/IF Image SCAP2 antibody [C2C3], C-term detects SKAP2 protein at cytoplasm by immunofluorescent analysis. Sample: HepG2 cells were fixed in 4% paraformaldehyde at RT for 15 min. Green: SKAP2 protein stained by SCAP2 antibody [C2C3], C-term , diluted at 1:500. Blue: Hoechst 33342 staining. IHC-P Image Immunohistochemical analysis of paraffin-embedded human lung cancer, using SCAP2, antibody at 1:100 dilution. 100 μL 3 to 4 Days
$466.18
Détails
Roussette (Chauve-souris) Chèvre Inconjugué ELISA, WB 100 μg 11 to 14 Days
$610.50
Détails
Humain Lapin Inconjugué IF/ICC, IHC, WB Western blot analysis of extracts of mouse lung, using SKAP2 antibody (ABIN5973835) at 1/1000 dilution. Immunohistochemistry of paraffin-embedded mouse stomach using SKAP2 antibody (ABIN5973835) at dilution of 1/100 (40x lens). 100 μL 11 to 16 Days
$426.40
Détails
Humain Lapin Inconjugué IHC, WB Western blot analysis of extracts from mouse spleen, using SKAP2 antibody. Lane 1 was treated with the blocking peptide. ABIN6272929 at 1/100 staining Human gastric tissue by IHC-P. The sample was formaldehyde fixed and a heat mediated antigen retrieval step in citrate buffer was performed. The sample was then blocked and incubated with the antibody for 1.5 hours at 22°C. An HRP conjugated goat anti-rabbit antibody was used as the secondary. 100 μL 11 to 12 Days
$390.77
Détails
Humain Lapin Inconjugué IF, IHC, WB Western blot analysis of extracts of mouse lung, using SKAP2 antibody. Immunohistochemistry of paraffin-embedded mouse stomach using SKAP2 antibody. 200 μL 12 to 14 Days
$438.90
Détails
Humain Lapin Inconjugué IF, IHC, WB Immunohistochemistry of paraffin-embedded mouse stomach using SKAP2 antibody at dilution of 1:100 (x40 lens). Immunohistochemistry of paraffin-embedded rat lung using SKAP2 antibody at dilution of 1:100 (x40 lens). 100 μL 11 to 13 Days
$366.77
Détails
Poulet Lapin Inconjugué WB 100 μL 11 to 14 Days
$551.83
Détails
Humain Lapin Inconjugué WB Western blot analysis in U937 cell line lysates (35ug/lane). 400 μL 2 to 3 Days
$515.63
Détails

anti-SKAP2 Anticorps mieux référencés

  1. Cow (Bovine) Polyclonal SKAP2 Primary Antibody pour ELISA, WB - ABIN546814 : Takahashi, Yamashita, Nagano, Nakamura, Ohmori, Avraham, Avraham, Yasuda, Matsumoto: Identification and characterization of a novel Pyk2/related adhesion focal tyrosine kinase-associated protein that inhibits alpha-synuclein phosphorylation. dans The Journal of biological chemistry 2003 (PubMed)

Plus d’anticorps contre SKAP2 partenaires d’interaction

Mouse (Murine) Src Kinase Associated Phosphoprotein 2 (SKAP2) interaction partners

  1. SKAP2 depletion also disrupted actin cap and cortical granule-free domain formation, and arrested a large proportion of oocytes at the telophase stage. Moreover, Arp2/3 complex and WAVE2 expression was decreased after the depletion of SKAP2 activity.

  2. Skap2 is essential to activate the beta2 integrins, and loss of Skap2 function is sufficient to cause a leukocyte adhesion deficiency (LAD)-like phenotype in mice.

  3. Macrophages assemble the appropriate motile machinery to infiltrate tumors and promote disease progression, and implicate SKAP2 as an attractive candidate for therapeutically targeting TAMs.

  4. RA70/Scap2 may be necessary for RA-induced neuronal differentiation from the posterior neuroectoderm.

  5. a novel role of SKAP-Hom and its phosphorylation in the regulation of cellular motility.

  6. integrin activation by the ADAP-SKAP55-signaling module controls the stability and duration of T cell-dendritic cell contacts during the progressive phases necessary for optimal T cell activation.

  7. Sirpalpha is not exclusively immunoinhibitory, and illuminate previously unexplained observations implicating Skap2 and Sirpalpha in mouse models of inflammatory disease.

  8. These results revealed an essential role for HSF4-mediated SKAP2 expression in the regulation of actin reorganization during lens differentiation.

  9. M-CSF receptor induces tyrosine phosphorylation of SKAP55R adaptor and its association with actin

  10. SKAP-HOM is required for proper activation of the immune system, likely by regulating the cross-talk between immunoreceptors and integrins.

  11. A signaling module comprising the cytosolic adapter proteins ADAP and SKAP55 is involved in TCR-mediated inside-out signaling and, the interaction between ADAP and SKAP55 is mandatory for integrin activation.

  12. Results describe a link between ADAP/SKAP-55 and the Rap1/RIAM complex and provide a potential new mechanism for T cell receptor-mediated integrin activation.

  13. SKAP-HOM expression in DCs is required for the induction of an optimal immune response; antigen-dependent conjugate formed between wild-type T cells and SKAP-HOM(-/-) DCs is delayed

Human Src Kinase Associated Phosphoprotein 2 (SKAP2) interaction partners

  1. Macrophages assemble the appropriate motile machinery to infiltrate tumors and promote disease progression, and implicate SKAP2 as an attractive candidate for therapeutically targeting TAMs.

  2. Skap2 is necessary for macrophage migration, chemotaxis, global actin reorganization and local actin reorganization upon integrin engagement.

  3. SKAP2 expression levels in NSCLC tissues could be a powerful biomarker of poor prognosis. Therefore, SKAP2 is a promising candidate molecular target for Non-small cell lung cancer treatment.

  4. results suggest that SKAP2 negatively regulates cell migration and tumor invasion in fibroblasts and glioblastoma cells by suppressing actin assembly induced by the WAVE2-cortactin complex

  5. analysis of substrate specificity of lymphoid-specific tyrosine phosphatase (Lyp) and identification of Src kinase-associated protein of 55 kDa homolog (SKAP-HOM) as a Lyp substrate

  6. cloning & characterization of an adaptor protein that functions as a downstream target for RAFTK & plays a role in alpha-synuclein phosphorylation

  7. studies provide insights into the molecular mechanism ofrelated adhesion focal tyrosine kinase (RAFTK) autophosphorylation and the specific role of Src in the regulation of RAFTK activation

  8. Overexpression of SKAP2 is associated with the development of pancreatic ductal adenocarcinoma

SKAP2 profil antigène

Profil protéine

The protein encoded by this gene belongs to the src family kinases. This protein is similar to the src kinase associated phosphoprotein 1. It is an adaptor protein that is thought to play an essential role in the src signaling pathway in various cells. It inhibits PTK2B/RAFTK activity and regulates alpha-synuclein phosphorylation.

Gene names and symbols associated with SKAP2

  • src kinase associated phosphoprotein 2 L homeolog (skap2.L) anticorps
  • SRC kinase associated phosphoprotein 2 (CCC13826_0176) anticorps
  • src family associated phosphoprotein 2 (Skap2) anticorps
  • src kinase associated phosphoprotein 2 (SKAP2) anticorps
  • src kinase associated phosphoprotein 2 (Skap2) anticorps
  • src kinase associated phosphoprotein 2 (skap2) anticorps
  • 2610021A10Rik anticorps
  • AA960083 anticorps
  • BB137539 anticorps
  • mSKAP55R anticorps
  • PRAP anticorps
  • RA70 anticorps
  • SAPS anticorps
  • SCAP2 anticorps
  • Scap55r anticorps
  • si:dz31b14.4 anticorps
  • si:dz227h09.6 anticorps
  • SKAP-HOM anticorps
  • SKAP55 anticorps
  • SKAP55R anticorps
  • zgc:65975 anticorps
  • zgc:158223 anticorps

Protein level used designations for SKAP2

src kinase-associated phosphoprotein 2-B , SRC kinase associated phosphoprotein 2 , SKAP55 homolog , SKAP55 homologue , Src-associated adaptor protein , pyk2/RAFTK-associated protein , src family-associated phosphoprotein 2 , src kinase-associated phosphoprotein 2 , src kinase-associated phosphoprotein 55-related protein , src-associated adapter protein with PH and SH3 domains , Fyn-associated phosphoprotein SKAP55 homologue , Pyk2/RAFTK-associated protein , SKAP-55HOM , retinoic acid-induced protein 70 , src family associated phosphoprotein 2 , src kinase-associated phosphoprotein of 55-related protein , src-associated adaptor protein , SKAP-HOM , SKAP55-HOM , Src kinase-associated phosphoprotein 2

GENE ID SPECIES
495326 Xenopus laevis
5596751 Campylobacter concisus 13826
54353 Mus musculus
8935 Homo sapiens
482366 Canis lupus familiaris
616545 Bos taurus
155183 Rattus norvegicus
100171875 Pongo abelii
368564 Danio rerio
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