UDP-Glucose Ceramide Glucosyltransferase (UGCG) Kits ELISA

Glycosphingolipids (GSLs) are a group of membrane components that contain lipid and sugar moieties. De plus, nous expédions UGCG Anticorps (53) et UGCG Protéines (8) et beaucoup plus de produits pour cette protéine.

list all ELISA KIts Gène GeneID UniProt
UGCG 7357 Q16739
UGCG 22234 O88693
UGCG 83626 Q9R0E0
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Top UGCG Kits ELISA sur anticorps-enligne.fr

Showing 10 out of 23 products:

Catalogue No. Reactivité Sensibilité Gamme Images Quantité Livraison Prix Détails
Souris 1.56 pg/mL 6.25-400 pg/mL Typical standard curve 96 Tests 15 to 18 Days
Humain 0.53 ng/mL 1.56 ng/mL - 100 ng/mL 96 Tests 13 to 16 Days
Humain 0.34 ng/mL 0.78-50 ng/mL   96 Tests 2 to 3 Days
Porc 0.938 ng/mL 1.563-100 ng/mL   96 Tests 12 to 14 Days
Poulet 0.938 ng/mL 1.563-100 ng/mL   96 Tests 12 to 14 Days
Cobaye 0.469 ng/mL 0.781-50 ng/mL   96 Tests 12 to 14 Days
Lapin 37.5 pg/mL 62.5-4000 pg/mL   96 Tests 12 to 14 Days
Singe 0.938 ng/mL 1.563-100 ng/mL   96 Tests 12 to 14 Days
Humain 0115 ng/mL 0.312 ng/mL - 20 ng/mL   96 Tests 15 to 17 Days
Rat 0216 ng/mL 0.625 ng/mL - 40 ng/mL   96 Tests 15 to 17 Days

Plus Kits ELISA pour UGCG partenaires d'interaction

Human UDP-Glucose Ceramide Glucosyltransferase (UGCG) interaction partners

  1. the GCS inhibitor lucerastat provides a viable mechanism to reduce Gb3 accumulation and lysosome volume, suitable for all Fabry patients regardless of genotype

  2. findings suggest that complex formation between SMS1 and GCS is part of a critical mechanism controlling the metabolic fate of Cer in the Golgi.

  3. Studies show a connection between UDP-glucose ceramide glucosyltransferase (UGCG) and multidrug resistance protein 1 (MDR1) overexpression and multidrug resistance development [Review].

  4. Results suggest that the changes of DNA methylation status of the glucosylceramide synthase (GCS) promoter correlates with multidrug resistance in breast cancer.

  5. Glucosylceramide synthase upregulation is associated with sorafenib resistance in hepatocellular carcinoma.

  6. GCS was upregulated in colorectal carcinoma tissues compared to control tissues.

  7. We found upregulation of specific sphingolipid enzymes, namely sphingomyelin synthase 1 (SMS1), sphingomyelinase 3 (SMPD3), and glucosylceramide synthase (GCS) in the endometrium of endometriotic women.

  8. Our data demonstrates a correlation between the expression of the GCS protein and ER-positive/HER-2 negative breast cancer

  9. our work indicates that some UGCG polymorphisms are modifying factors in the severity of GD.

  10. GCS was upregulated in PTCs and might be an independent factor affecting prognosis.

  11. Glucosylceramide synthase mRNA were reduced by 62%.

  12. The results thus show that ARF6 regulates neuronal differentiation through an effect on glucosylceramide synthase and glucosylceramide levels.

  13. DOX could modulate the expression of GCS through the Sp1 site of GCS promoter in ERalpha-positive breast cancer cells

  14. Ceramide glycosylation catalyzed by glucosylceramide synthase is important for cancer stem cells in drug resistance and tumorigenesis.

  15. Data indicate that a high expression of glucosylceramide synthase (GCS) seemed to be an indicator of poor prognosis.

  16. The authors conclude that hepatitis C virus proteins, especially NS5A and NS5B, have positive effects on the expression of human GlcT-1.

  17. GlcT-1 is up-regulated at the mRNA and protein levels during the course of U937 differentiation, resulting in increased amounts of GlcCer.

  18. Data show that nilotinib induces apoptosis through upregulating ceramide synthase genes and downregulating SK-1 in CML cells in addition to inhibition of BCR/ABL.

  19. GCS overexpression was highly associated with ER-positive and HER2-positive breast cancer with metastasis.

  20. Data show that GCS silencing increased the levels of phosphorylated p53 and p53-responsive genes.

Mouse (Murine) UDP-Glucose Ceramide Glucosyltransferase (UGCG) interaction partners

  1. The cell division gene PCNA was significantly overexpressed in SK2(-/-) cells, suggesting a cross regulation between sphingosine kinases and Ceramide glucosyltransferase.

  2. we report the development of a novel, orally available glucosylceramide synthase inhibitor (Genz-682452) with pharmacological and safety profiles that have potential for treating Fabry disease.

  3. These results suggest that neuronal glucosylceramide synthase expression modulates mediobasal hypothalamus insulin signaling and white adipose tissue function in fasted mice.

  4. we measured the expression and activities of Pgp and GCS, UDP-glucose levels, cellular uptake of C12-NBD-ceramide (a fluorescent analogue of ceramide) and ceramide-induced cell death in S and R cells.

  5. Data indicate that verexpression of glucosylceramide synthase in myotubes induces glucosylceramide but enhances insulin signaling.

  6. Data indicate that mice fed D- threo-1-phenyl-2-decanoylamino-3-morpholino-1-propanol (D-PDMP), an inhibitor of glucosylceramide synthase and lactosylceramide synthase showed marked reduction in tumor volume.

  7. The present work demonstrates that hypothalamic integration of metabolic signals requires neuronal expression of glucosylceramide synthase (GCS; UDP-glucose:ceramide glucosyltransferase).

  8. Data indicate that mice with cerebroside sulfotransferases (Cst) and UDP-glucose:ceramide glucosyltransferase (Ugcg)/Cst deficiency had lower ammonium excretion.

  9. glycosphingolipids in hepatocytes are not essential for sterol, glucose, or lipoprotein metabolism. Ugcg inhibitors exert their effect on hepatocytes either independently of GSL or mediated by other (liver) cell types.

  10. Ugcg and Ugt8a deficient oligodendroglial did not exhibit any phenotypic or myelin structural abnormalities; abundant and structurally intact myelin can form in their absence

  11. Shortly after birth UgcG deficient mice showed dysfunction of cerebellum and peripheral nerves, associated with structural defects

UGCG profil antigène

Antigen Summary

Glycosphingolipids (GSLs) are a group of membrane components that contain lipid and sugar moieties. They are present in essentially all animal cells and are believed to have important roles in various cellular processes. UDP-glucose ceramide glucosyltransferase catalyzes the first glycosylation step in glycosphingolipid biosynthesis. The product, glucosylceramide, is the core structure of more than 300 GSLs. UGCG is widely expressed and transcription is upregulated during keratinocyte differentiation.

Gene names and symbols associated with UGCG

  • UDP-glucose ceramide glucosyltransferase (UGCG) anticorps
  • UDP-glucose ceramide glucosyltransferase S homeolog (ugcg.S) anticorps
  • UDP-glucose ceramide glucosyltransferase (ugcg) anticorps
  • UDP-glucose ceramide glucosyltransferase (Ugcg) anticorps
  • AU043821 anticorps
  • C80537 anticorps
  • cb539 anticorps
  • Epcs21 anticorps
  • GCS anticorps
  • GlcT-1 anticorps
  • GLCT1 anticorps
  • sb:cb539 anticorps
  • ugcg anticorps
  • ugcgb anticorps
  • Ugcgl anticorps
  • xlcgt anticorps
  • zgc:112506 anticorps

Protein level used designations for UGCG

ceramide glucosyltransferase , UDP-glucose ceramide glucosyltransferase b , ceramide glucosyltransferase b , ceramide glucosyltransferase-B , GlcT , GLCT-1 , UDP-glucose:N-acylsphingosine D-glucosyltransferase , glucosylceramide synthase , GCS , ectoplacental cone, invasive trophoblast giant cells, extraembryonic ectoderm and chorion sequence 21 , UDP-glucose:ceramide glycosyltransferase

464660 Pan troglodytes
495444 Xenopus laevis
548887 Xenopus (Silurana) tropicalis
553944 Danio rerio
707875 Macaca mulatta
7357 Homo sapiens
22234 Mus musculus
83626 Rattus norvegicus
514357 Bos taurus
427335 Gallus gallus
481666 Canis lupus familiaris
100152737 Sus scrofa
100730880 Cavia porcellus
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