anti-Ubiquitin-Conjugating Enzyme E2A (ube2a) Anticorps

The modification of proteins with ubiquitin is an important cellular mechanism for targeting abnormal or short-lived proteins for degradation. De plus, nous expédions Ubiquitin-Conjugating Enzyme E2A Kits (14) et Ubiquitin-Conjugating Enzyme E2A Protéines (13) et beaucoup plus de produits pour cette protéine.

afficher tous les anticorps Gène GeneID UniProt
ube2a 7319 P49459
ube2a 22209 Q9Z255
ube2a 298317  
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Top anti-Ubiquitin-Conjugating Enzyme E2A Anticorps sur anticorps-enligne.fr

Showing 10 out of 54 products:

Catalogue No. Reactivité Hôte Conjugué Application Images Quantité Fournisseur Livraison Prix Détails
Humain Lapin Inconjugué ICC, IF, IHC, IHC (p), WB Detection of Human Rad6 by Western Blot. Samples: Whole cell lysate (50 mcg) from HEK293T cells. Antibody: ABIN151985 used at the indicated concentrations. Detection: Chemiluminescence. Western Blot: HR6A/UBE2A Antibody [ABIN151985] - Whole cell lysate (50 ug) from HeLa and 293T cells prepared using NETN lysis buffer. Antibody: Affinity purified rabbit anti-Rad6 antibody used for WB at 0.04 ug/ml. Detection: Chemiluminescence with an exposure time of 30 seconds. 100 μL Connectez-vous pour afficher 7 to 9 Days
$486.94
Détails
Humain Lapin Inconjugué ICC, IF, WB WB Image Sample (30 ug of whole cell lysate) A: Hela 10% SDS PAGE antibody diluted at 1:1000 ICC/IF Image UBE2A antibody detects UBE2A protein at cytoplasm and nucleus by immunofluorescent analysis. Sample: A375 cells were fixed in 4% paraformaldehyde at RT for 15 min. Green: UBE2A protein stained by UBE2A antibody , diluted at 1:500. Blue: Hoechst 33342 staining. Scale bar = 10 μm. 100 μL Connectez-vous pour afficher 1 to 2 Days
$358.60
Détails
Humain Souris Inconjugué ELISA, WB   0.1 mg Connectez-vous pour afficher 8 to 11 Days
$450.00
Détails
Humain Lapin Inconjugué ICC, IF, WB Western Blot: UBE2A Antibody [NBP2-20780] - Sample (50 ug of whole cell lysate) A: Mouse Brain, 15% SDS PAGE gel, diluted at 1:500. Immunocytochemistry/Immunofluorescence: UBE2A Antibody [NBP2-20780] - Sample: HeLa cells were fixed in 4% paraformaldehyde at RT for 15 min. Green: UBE2A protein stained by UBE2A antibody diluted at 1:500. Blue: Hoechst 33342 staining. 0.1 mL Connectez-vous pour afficher 8 to 11 Days
$447.56
Détails
Humain Lapin Inconjugué ICC, IF, IHC, IHC (p), WB Detection of Human Rad6 by Western Blot. Samples: Whole cell lysate (50 mcg) from HEK293T cells. Antibody: ABIN151986 used at the indicated concentrations. Detection: Chemiluminescence. Western Blot: HR6A/UBE2A Antibody [ABIN151986] - Whole cell lysate (50 ug) from HeLa and 293T cells Prepared using NETN lysis buffer. Antibody: Affinity purified rabbit anti-Rad6 antibody used for WB at 0.4 ug/ml. Detection: Chemiluminescence with an exposure time of 3 minutes. 100 μL Connectez-vous pour afficher 7 to 9 Days
$486.94
Détails
Humain Lapin Inconjugué WB Detection of Human Rad6 by Western Blot. Samples: Whole cell lysate (50 mcg) from HEK293T cells. Antibody: ABIN151987 used at the indicated concentrations. Detection: Chemiluminescence. Western Blot: HR6A/UBE2A Antibody [ABIN151987] - Whole cell lysate (50 ug) from HeLa and 293T cells prepared using NETN lysis buffer. Antibody: Affinity purified rabbit anti-Rad6 antibody used for WB at 0.2 ug/ml. Detection: Chemiluminescence with an exposure time of 3 minutes. 100 μL Connectez-vous pour afficher 7 to 9 Days
$486.94
Détails
Humain Souris Inconjugué DB 50 μg Connectez-vous pour afficher 6 to 8 Days
$285.71
Détails
Humain Lapin Inconjugué IHC, WB Western blot analysis of extracts of mouse kidney, using UBE2A antibody. Immunohistochemistry of paraffin-embedded mouse stomach using UBE2A antibody. 100 μL Connectez-vous pour afficher 16 Days
$323.13
Détails
Humain Lapin HRP IHC (p), WB   100 μL Connectez-vous pour afficher 14 to 21 Days
$405.90
Détails
Humain Lapin Cy5.5 IF (p)   100 μL Connectez-vous pour afficher 14 to 21 Days
$405.90
Détails

ube2a Anticorps par réactivité, application, clonalité et conjugué

Attributs Application Hôte Clonalité Conjugué
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anti-Ubiquitin-Conjugating Enzyme E2A Anticorps mieux référencés

  1. Human Polyclonal ube2a Primary Antibody pour ICC, IF - ABIN151985 : Dul, Walworth: The plant homeodomain fingers of fission yeast Msc1 exhibit E3 ubiquitin ligase activity. dans The Journal of biological chemistry 2007 (PubMed)
    Show all 2 Pubmed References

Plus d’anticorps contre Ubiquitin-Conjugating Enzyme E2A partenaires d’interaction

Human Ubiquitin-Conjugating Enzyme E2A (ube2a) interaction partners

  1. RAD6 promotes proteasome activity and nuclear translocation by enhancing the degradation of PSMF1 (Montrer PSMF1 Anticorps) and the lamin B receptor (Montrer LBR Anticorps).

  2. Data show that the ubiquitin-conjugating enzyme E2 RAD6A/B-MDM2 ubiquitin ligase machinery regulates anti-silencing function 1A protein (ASF1A) degradation.

  3. Results showed KCMF1 (Montrer KCMF1 Anticorps) C-terminus binds directly to RAD6, whereas N-terminal domains interact with UBR4 (Montrer UBR4 Anticorps) and point mutations found in X-linked intellectual disability (XLID) patients specifically lose the interaction with KCMF1 (Montrer KCMF1 Anticorps) and UBR4 (Montrer UBR4 Anticorps).

  4. This study investigates clinical and molecular data of two unrelated, affected males with chromosome Xq24 deletions encompassing UBE2A.

  5. RAD6 physically interacts with heterochromatin protein 1alpha and ubiquitinates HP1alpha (Montrer CBX5 Anticorps) at residue K154, thereby promoting heterochromatin protein 1alpha degradation through the autophagy pathway

  6. HHR6 and hRad18 (Montrer RAD18 Anticorps) can monoubiquitinate FANCD2 (Montrer FANCD2 Anticorps) at lysine 561 in vitro. This activity may represent a novel stress response pathway.

  7. RNF168 (Montrer RNF168 Anticorps), in complex with RAD6A or RAD6B (Montrer UBE2B Anticorps), is activated in the DNA-damage-induced protein ubiquitination cascade.

  8. RAD6A is a regulator of Parkin (Montrer PARK2 Anticorps)-dependent mitophagy plays a critical role in maintaining neuronal function.

  9. UBE2A specifically interacts with CDK9 (Montrer CDK9 Anticorps), but not CDK2 (Montrer CDK2 Anticorps) and is phosphorylated by CDK9 (Montrer CDK9 Anticorps) in vitro.

  10. RAD6 can form a ternary complex with MDM2 (Montrer MDM2 Anticorps) and p53 (Montrer TP53 Anticorps) that contributes to the degradation of p53 (Montrer TP53 Anticorps).

Mouse (Murine) Ubiquitin-Conjugating Enzyme E2A (ube2a) interaction partners

  1. results indicate a causal role of UBE2A in learning and mGLUR (Montrer GRM8 Anticorps)-dependent long-term depression

  2. RNF168 (Montrer RNF168 Anticorps), in complex with RAD6A or RAD6B (Montrer UBE2B Anticorps), is activated in the DNA-damage-induced protein ubiquitination cascade.

  3. Disruption of pre-TCR expression accelerates lymphomagenesis in E2A (Montrer TCF3 Anticorps)-deficient mice.

  4. signaling through Notch (Montrer NOTCH1 Anticorps) modulates the turnover of E2A (Montrer TCF3 Anticorps) proteins

  5. absence of mHR6A in oocytes prevents development beyond the embryonic two-cell stage

Ubiquitin-Conjugating Enzyme E2A (ube2a) profil antigène

Profil protéine

The modification of proteins with ubiquitin is an important cellular mechanism for targeting abnormal or short-lived proteins for degradation. Ubiquitination involves at least three classes of enzymes: ubiquitin-activating enzymes, or E1s, ubiquitin-conjugating enzymes, or E2s, and ubiquitin-protein ligases, or E3s. This gene encodes a member of the E2 ubiquitin-conjugating enzyme family. This enzyme is required for post-replicative DNA damage repair. Multiple alternatively spliced transcript variants have been found for this gene and they encode distinct isoforms.

Gene names and symbols associated with ube2a

  • ubiquitin conjugating enzyme E2 A (UBE2A) anticorps
  • ubiquitin conjugating enzyme E2 A L homeolog (ube2a.L) anticorps
  • ubiquitin conjugating enzyme E2 A (ube2a) anticorps
  • ubiquitin-conjugating enzyme E2A (RAD6 homolog) (ube2a) anticorps
  • ubiquitin-conjugating enzyme E2A (Ube2a) anticorps
  • BHR6A anticorps
  • HHR6A anticorps
  • HR6A anticorps
  • Mhr6a anticorps
  • mp:zf637-2-000771 anticorps
  • MRXS30 anticorps
  • MRXSN anticorps
  • RAD6A anticorps
  • si:bz46j2.4 anticorps
  • UBC2 anticorps
  • wu:fa01h11 anticorps

Protein level used designations for ube2a

ubiquitin-conjugating enzyme E2 A , ubiquitin-conjugating enzyme E2A (RAD6 homolog) , ubiquitin-conjugating enzyme E2A , RAD6 homolog A , ubiquitin carrier protein A , ubiquitin-protein ligase A , ubiquitin-conjugating enzyme E2A, RAD6 homolog , ubiquitin-conjugating enzyme HR6A

GENE ID SPECIES
282107 Bos taurus
398788 Xenopus laevis
448176 Xenopus (Silurana) tropicalis
492095 Canis lupus familiaris
693716 Macaca mulatta
737175 Pan troglodytes
797853 Danio rerio
100058679 Equus caballus
100195873 Salmo salar
100217902 Taeniopygia guttata
7319 Homo sapiens
22209 Mus musculus
298317 Rattus norvegicus
100154142 Sus scrofa
395672 Gallus gallus
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