WD Repeat Domain 83 Protéines (wdr83)

wdr83 encodes a member of the WD-40 protein family. De plus, nous expédions WD Repeat Domain 83 Anticorps (82) et beaucoup plus de produits pour cette protéine.

afficher tous les protéines Gène GeneID UniProt
wdr83 84292 Q9BRX9
Souris wdr83 wdr83 67836 Q9DAJ4
wdr83 288924 Q5BLX8
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Top WD Repeat Domain 83 Protéines sur anticorps-enligne.fr

Showing 5 out of 7 products:

Catalogue No. Origin Source Conjugué Images Quantité Livraison Prix Détails
Cellules d'insectes Humain His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg 50 Days
HEK-293 Cells Humain Myc-DYKDDDDK Tag Validation with Western Blot 20 μg 11 Days
Wheat germ Humain GST tag 10 μg 11 to 12 Days
Levure Xenopus laevis His tag   1 mg 60 to 71 Days
Levure Rat His tag   1 mg 60 to 71 Days

wdr83 Protéines protéines par origine et source

Origin Exprimée danse Conjugué
Human , ,
, ,
Rat (Rattus)

Plus protéines pour WD Repeat Domain 83 (wdr83) partenaires d'interaction

Human WD Repeat Domain 83 (wdr83) interaction partners

  1. Morg1 facilitates Par6-aPKC binding to Crb3 for definition of apical identity of epithelial cells.

  2. WDR83 and DHPS were capable of forming an RNA duplex at overlapping 3' untranslated regions and this duplex increased their mutual stability, which was required for the bidirectional regulation.

  3. Includes the identification of this protein in C complex spliceosomes.

  4. Functional characterization of the homologous rat gene.

  5. Component of a modular scaffold system that participates in the regulation of agonist-specific ERK signaling.

  6. Morg1 expression is reduced in human brain tissue with ischemic damage. Reactive astrocytes in the surrounding brain tissue showed strong Morg1 expression.

Mouse (Murine) WD Repeat Domain 83 (wdr83) interaction partners

  1. MORG1 heterozygosity protects against histological renal damage and shows anti-inflammatory effects in a murine endotoxemia model.

  2. High MORG1 expression is associated with diabetic nephropathy.

  3. heterozygous deficiency protects against kidney injury induced by systemic hypoxia

  4. this study shows for the first time in various renal cells that ANG II modulates Morg1 expression and HIF-1alpha transcriptional activity via cell type-specific mechanisms, demonstrating a novel mechanism by which ANG II may contribute to renal disease.

  5. The major finding of this study is that Morg1+/- mice are partially protected from cerebral ischemia and reperfusion injury in comparison to the WT (Morg1+/+) animals

  6. Morg1 may be a novel therapeutic target to limit renal injury after ischemia-reperfusion

Profil protéine WD Repeat Domain 83 (wdr83)

Profil protéine

This gene encodes a member of the WD-40 protein family. The protein is proposed to function as a molecular scaffold for various multimeric protein complexes. The protein associates with several components of the extracellular signal-regulated kinase (ERK) pathway, and promotes ERK activity in response to serum or other signals. The protein also interacts with egl nine homolog 3 (EGLN3, also known as PHD3) and regulates expression of hypoxia-inducible factor 1, and has been purified as part of the spliceosome. Alternative splicing results in multiple transcript variants.

Gene names and symbols associated with WD Repeat Domain 83 Protéines (wdr83)

  • WD repeat domain 83 (WDR83)
  • WD repeat domain containing 83 (Wdr83)
  • WD repeat domain 83 (Wdr83)
  • WD repeat domain 83 L homeolog (wdr83.L)
  • WD repeat domain containing 83 (wdr83)
  • 1500041N16Rik Protéine
  • MAPK organizer 1 Protéine
  • morg1 Protéine
  • RGD1306947 Protéine
  • wu:fj29g04 Protéine
  • zgc:92654 Protéine

Protein level used designations for WD Repeat Domain 83 Protéines (wdr83)

MAPK organizer 1 , WD repeat domain-containing protein 83 , mitogen-activated protein kinase organizer 1 , MAPK cascade scaffold protein , WD repeat protein Morg1 , Mitogen-activated protein kinase organizer 1 , fj29g04

84292 Homo sapiens
67836 Mus musculus
288924 Rattus norvegicus
734767 Xenopus laevis
100731190 Cavia porcellus
436702 Danio rerio
484931 Canis lupus familiaris
780845 Bos taurus
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