HLA-DR anticorps
(4 références)-
- Antigène Tous les produits HLA-DR
- HLA-DR
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Reactivité
- Humain, Chien, Non-Human Primate
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Hôte
- Souris
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Clonalité
- Monoclonal
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Conjugué
- Cet anticorp HLA-DR est non-conjugé
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Application
- Flow Cytometry (FACS), Western Blotting (WB), Immunoprecipitation (IP), Immunohistochemistry (Frozen Sections) (IHC (fro)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunocytochemistry (ICC)
- Specificité
- The mouse monoclonal antibody L243 recognizes specifically an extracellular epitope on HLA-DR molecules, both peptide-loaded and empty.
- Réactivité croisée (Details)
- Human, Non-Human Primates, Canine (Dog)
- Purification
- Purified by protein-A affinity chromatography.
- Pureté
- > 95 % (by SDS-PAGE)
- Immunogène
- Human B lymphocytes
- Clone
- L243
- Isotype
- IgG2a kappa
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anti-HLA-DR (HLA-DR) antibody (FITC)
HLA-DR Reactivité: Humain FACS Hôte: Souris Monoclonal MEM-12 FITC
anti-HLA-DR (HLA-DR) antibodyHLA-DR Reactivité: Humain FACS, WB, IHC, ISt, StM Hôte: Souris Monoclonal TAL 1B5 unconjugated
anti-HLA-DR (HLA-DR) antibodyHLA-DR Reactivité: Humain FACS, WB, IP Hôte: Souris Monoclonal MEM-12 unconjugated
anti-HLA-DR (HLA-DR) antibody (PE)HLA-DR Reactivité: Humain, Chien, Non-Human Primate FACS Hôte: Souris Monoclonal L243 PE
anti-HLA-DR (HLA-DR) antibodyHLA-DR Reactivité: Humain FACS, WB, IHC, IF, ISt, StM Hôte: Souris Monoclonal SPM289 unconjugated
anti-HLA-DR (HLA-DR) antibodyHLA-DR Reactivité: Humain FACS, IP Hôte: Souris Monoclonal HL-39 unconjugated
anti-HLA-DR (HLA-DR) antibodyHLA-DR Reactivité: Humain, Chien, Non-Human Primate FACS, WB, IP, IHC (fro), IHC (p), ICC, Func Hôte: Souris Monoclonal L243 unconjugated
anti-HLA-DR (HLA-DR) antibody (PE)HLA-DR Reactivité: Humain FACS Hôte: Souris Monoclonal MEM-12 PE
anti-HLA-DR (HLA-DR) antibody (APC)HLA-DR Reactivité: Humain FACS Hôte: Souris Monoclonal MEM-12 APC
anti-HLA-DR (HLA-DR) antibody (PerCP)HLA-DR Reactivité: Humain FACS Hôte: Souris Monoclonal MEM-12 PerCP
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- Indications d'application
- Flow cytometry: Recommended dilution: 1-4 μg/mL.
- Restrictions
- For Research Use only
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- Concentration
- 1 mg/mL
- Buffer
- Phosphate buffered saline (PBS), pH 7.4, 15 mM sodium azide
- Agent conservateur
- Sodium azide
- Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Conseil sur la manipulation
- Do not freeze.
- Stock
- 4 °C
- Stockage commentaire
- Store at 2-8°C. Do not freeze.
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: "Monoclonal antibodies directed to CD20 and HLA-DR can elicit homotypic adhesion followed by lysosome-mediated cell death in human lymphoma and leukemia cells." dans: The Journal of clinical investigation, Vol. 119, Issue 8, pp. 2143-59, (2009) (PubMed).
: "MHC class II stabilization at the surface of human dendritic cells is the result of maturation-dependent MARCH I down-regulation." dans: Proceedings of the National Academy of Sciences of the United States of America, Vol. 105, Issue 9, pp. 3491-6, (2008) (PubMed).
: "Lipid raft-dependent and -independent signaling through HLA-DR molecules." dans: The Journal of biological chemistry, Vol. 278, Issue 9, pp. 7099-107, (2003) (PubMed).
: "Zwitterionic polysaccharides stimulate T cells by MHC class II-dependent interactions." dans: Journal of immunology (Baltimore, Md. : 1950), Vol. 169, Issue 11, pp. 6149-53, (2002) (PubMed).
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: "Monoclonal antibodies directed to CD20 and HLA-DR can elicit homotypic adhesion followed by lysosome-mediated cell death in human lymphoma and leukemia cells." dans: The Journal of clinical investigation, Vol. 119, Issue 8, pp. 2143-59, (2009) (PubMed).
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- Antigène
- HLA-DR
- Autre désignation
- HLA-DR (HLA-DR Produits)
- Sujet
- HLA-DR, a member of MHC class II glycoproteins, that bind intracellularly processed peptides and present them to the Th cells, is composed of 36 kDa alpha chain and 27 kDa beta chain, both anchored in the plasma membrane. Together with other MHC II molecules HLA-DR plays a central role in the immune system.
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