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HLA-DR anticorps

HLA-DR Reactivité: Humain FACS, IP Hôte: Souris Monoclonal HL-39 unconjugated
N° du produit ABIN94340
  • Antigène Tous les produits HLA-DR
    HLA-DR
    Reactivité
    • 141
    • 23
    • 20
    • 19
    • 19
    • 14
    • 11
    • 8
    • 6
    • 4
    • 3
    • 3
    • 2
    • 1
    Humain
    Hôte
    • 123
    • 12
    • 10
    Souris
    Clonalité
    • 139
    • 5
    Monoclonal
    Conjugué
    • 43
    • 18
    • 17
    • 11
    • 9
    • 6
    • 4
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    • 3
    • 3
    • 3
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    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Cet anticorp HLA-DR est non-conjugé
    Application
    • 123
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    • 1
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    Flow Cytometry (FACS), Immunoprecipitation (IP)
    Specificité
    The antibody HL-39 recognizes an extracellular common epitope on human HLA-DR, which is dependent on the association of alpha and beta chains. Recognized epitope is conserved after fixation with glutaraldehyde and formaldehyde. DR is the isotype of human MHC Class II molecules expressed on antigen-presenting cells (APC, dendritic cells, B lymphocytes, monocytes, macrophages).
    Réactivité croisée (Details)
    Human
    Purification
    Purified by protein-A affinity chromatography.
    Pureté
    > 95 % (by SDS-PAGE)
    Immunogène
    Raji Burkitt's lymphoma cell line
    Clone
    HL-39
    Isotype
    IgG3
  • Indications d'application
    Flow cytometry: Recommended dilution: 0.5-4 μg/mL.
    Restrictions
    For Research Use only
  • Concentration
    1 mg/mL
    Buffer
    Phosphate buffered saline (PBS), pH 7.4, 15 mM sodium azide
    Agent conservateur
    Sodium azide
    Précaution d'utilisation
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Conseil sur la manipulation
    Do not freeze.
    Stock
    4 °C
    Stockage commentaire
    Store at 2-8°C. Do not freeze.
  • Hovden, Karlsen, Jonsson, Aarstad, Appel: "Maturation of monocyte derived dendritic cells with OK432 boosts IL-12p70 secretion and conveys strong T-cell responses." dans: BMC immunology, Vol. 12, pp. 2, (2011) (PubMed).

    Horejsí, N?mec, Angelisová, Kristofová, Gorga, Hilgert: "Characterization of seven new monoclonal antibodies against human DR, DR + DP and DQ1 + DQ3 antigens." dans: Tissue antigens, Vol. 28, Issue 5, pp. 288-97, (1987) (PubMed).

  • Antigène
    HLA-DR
    Autre désignation
    HLA-DR (HLA-DR Produits)
    Sujet
    HLA-DR, a member of MHC class II glycoproteins, that bind intracellularly processed peptides and present them to the Th cells, is composed of 36 kDa alpha chain and 27 kDa beta chain, both anchored in the plasma membrane. Together with other MHC II molecules HLA-DR plays a central role in the immune system.
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