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HLA-DR anticorps

HLA-DR Reactivité: Humain FACS, WB, IP Hôte: Souris Monoclonal MEM-12 unconjugated
N° du produit ABIN125741
  • Antigène Tous les produits HLA-DR
    HLA-DR
    Reactivité
    • 141
    • 23
    • 20
    • 19
    • 19
    • 14
    • 11
    • 8
    • 6
    • 4
    • 3
    • 3
    • 2
    • 1
    Humain
    Hôte
    • 123
    • 12
    • 10
    Souris
    Clonalité
    • 139
    • 5
    Monoclonal
    Conjugué
    • 43
    • 18
    • 17
    • 11
    • 9
    • 6
    • 4
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    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Cet anticorp HLA-DR est non-conjugé
    Application
    • 123
    • 36
    • 29
    • 22
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    • 12
    • 10
    • 9
    • 7
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    • 5
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    • 1
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    Flow Cytometry (FACS), Western Blotting (WB), Immunoprecipitation (IP)
    Specificité
    The antibody MEM-12 recognizes a common extracellular epitope on human HLA-DR which is dependent on the association of alpha and beta chains. DR is the isotype of human MHC Class II molecules expressed on antigen-presenting cells (APC, dendritic cells, B lymphocytes, monocytes, macrophages).
    Réactivité croisée (Details)
    Human
    Purification
    Purified by protein-A affinity chromatography.
    Pureté
    > 95 % (by SDS-PAGE)
    Immunogène
    thymocyte membrane
    Clone
    MEM-12
    Isotype
    IgG1
  • Indications d'application
    Flow cytometry: Recommended dilution: 2 μg/mL, positive control: B-lymphocytes, monocytes, DAUDI cell line, RAJI cell line.
    Western blotting and Immunoprecipitation: Positive control: B-lymphocytes, monocytes, DAUDI cell line, RAJI cell line, non-reducing conditions.
    Restrictions
    For Research Use only
  • Concentration
    1 mg/mL
    Buffer
    Phosphate buffered saline (PBS), pH 7.4, 15 mM sodium azide
    Agent conservateur
    Sodium azide
    Précaution d'utilisation
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Conseil sur la manipulation
    Do not freeze.
    Stock
    4 °C
    Stockage commentaire
    Store at 2-8°C. Do not freeze.
  • Horejsí, N?mec, Angelisová, Kristofová, Gorga, Hilgert: "Characterization of seven new monoclonal antibodies against human DR, DR + DP and DQ1 + DQ3 antigens." dans: Tissue antigens, Vol. 28, Issue 5, pp. 288-97, (1987) (PubMed).

  • Antigène
    HLA-DR
    Autre désignation
    HLA-DR (HLA-DR Produits)
    Sujet
    HLA-DR, a member of MHC class II glycoproteins, that bind intracellularly processed peptides and present them to the Th cells, is composed of 36 kDa alpha chain and 27 kDa beta chain, both anchored in the plasma membrane. Together with other MHC II molecules HLA-DR plays a central role in the immune system.
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