HLA-DR anticorps

N° du produit ABIN7449537

Cet anticorps anti-HLA-DR Monoclonal Souris (Clone LN3) (ABIN7449537) détecte spécifiquement HLA-DR dans FACS, WB, IHC, ICC et IF (p). L’anticorps est réactif avec des échantillons de Humain.

Aperçu rapide pour HLA-DR anticorps (ABIN7449537)

Antigène: HLA-DR

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp HLA-DR est non-conjugé

Application: Flow Cytometry (FACS), Western Blotting (WB), Immunohistochemistry (IHC), Immunocytochemistry (ICC), Immunofluorescence (Paraffin-embedded Sections) (IF (p))

Clone: LN3

Détail du produit anti-HLA-DR anticorps

Fonction: Mouse anti-HLA-DR Monoclonal Antibody Purified [LN3]

Purification: Purified

Immunogène: Activated human peripheral blood mononuclear cells

Isotype: IgG2b

Information d'application

Indications d'application:

IHC-IF: 1:100 to 1:500. Epitope retrieval with citrate buffer pH 6.0 is recommended for FFPE cell sections.

IHC: 1:100 - 1:500. Epitope retrieval with citrate buffer pH 6.0 is recommended for FFPE tissue sections.

ICC: 1:100 - 1:500. Epitope retrieval with citrate buffer pH 6.0 is recommended for FFPE cell sections.

WB: 17:40:00

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 50 μg/mL

Buffer: Phosphate Buffered Saline (PBS) with 0.1 % BSA and 0.09 % Sodium Azide

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C

Stockage commentaire: 2 - 8 °C

Date de péremption: 12 months

Détails sur HLA-DR

Antigène: HLA-DR

Autre désignation: HLA-DR

Sujet: In humans, Major Histocompatibility Locus (MHC) class II molecules are encoded by three different loci, HLA-DR, -DQ, and -DP, which display ~70 % similarity to each other. Polymorphism is a notable feature of MHC class II genes. HLA-DR, HLA-DP, and HLA-DQ are heterodimeric cell surface glycoproteins comprised of an α (heavy) chain and a β (light) chain. They are expressed on B cells, activated T cells, monocytes/macrophages, dendritic cells, and other non-professional APCs. In conjunction with the CD3/TCR complex and CD4 Molecules, HLA-DR is critical for efficient peptide presentation to CD4+ T cells. Variations in the HLA gene expression are crucial to graft survival.

ID gène: 3122

UniProt: P01903

Pathways: Human Leukocyte Antigen (HLA) in Adaptive Immune Response