Interleukin 17a anticorps
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- Antigène Voir toutes Interleukin 17a (IL17A) Anticorps
- Interleukin 17a (IL17A) (Interleukin 17A (IL17A))
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Reactivité
- Humain
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Hôte
- Lapin
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Clonalité
- Polyclonal
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Conjugué
- Cet anticorp Interleukin 17a est non-conjugé
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Application
- ELISA, Western Blotting (WB)
- Specificité
- Anti-IL-17A Antibody was affinity purified from monospecific antiserum by Protein A Purification. In ELISA and other immunoreactive assays, this antibody will recognize both native and recombinant human IL17-A in cell supernatants and certain body fluids. A control of similarly diluted normal rabbit IgG is recommended. Cross-reactivity with IL-17 from other sources has not been determined.
- Attributs du produit
- IL17-A (also known as Interleukin-17) is a proinflammatory cytokine produced by activated T cells. This cytokine regulates the activities of NF-kappaB and mitogen-activated protein kinases. This cytokine can stimulate the expression of IL6 and cyclooxygenase-2 (PTGS2/COX-2), as well as enhance the production of nitric oxide (NO). High levels of this cytokine are associated with several chronic inflammatory diseases including rheumatoid arthritis, psoriasis and multiple sclerosis. IL17-A is the founding member of a group of cytokines called the IL-17 family. IL17-A was originally identified as a transcript from a rodent T-cell hybridoma. To elicit its functions, IL17 binds to a type I cell surface receptor called IL17R of which there are at least three variants IL17RA, IL17RB, and IL17RC. Anti-IL-17 antibody is ideal for investigators involved in cytokines, growth factors, cancer, and immunology reseach.
- Immunogène
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IL-17A Antibody was prepared from whole rabbit serum produced by repeated immunizations with full length recombinant human IL17-A protein.
Immunogen Type: RecombinantProtein - Isotype
- IgG
- Top Product
- Discover our top product IL17A Anticorps primaire
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- Indications d'application
- IL-17-A antibody has been tested for use in ELISA and western blotting. By western blot a band approximately ~17.5 kDa in size corresponding to human IL-17-A protein is expected in the appropriate cell lysate or extract. Specific conditions for reactivity should be optimized by the end user.
- Commentaires
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Gene Name: IL17A
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 1.0 mg/mL
- Buffer
- 0.02 M Potassium Phosphate, 0.15 M Sodium Chloride, pH 7.2
- Agent conservateur
- Sodium azide
- Précaution d'utilisation
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Stock
- 4 °C/-20 °C
- Stockage commentaire
- Store vial at 4 °C prior to restoration. For extended storage aliquot contents and freeze at -20 °C or below. Avoid cycles of freezing and thawing. Centrifuge product if not completely clear after standing at room temperature. This product is stable for several weeks at 4 °C as an undiluted liquid. Dilute only prior to immediate use. Expiration date is three (3) months from date of opening.
- Date de péremption
- 3 months
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Interleukin-17A inhibits adipocyte differentiation in human mesenchymal stem cells and regulates pro-inflammatory responses in adipocytes." dans: Biochemical pharmacology, Vol. 77, Issue 12, pp. 1835-44, (2009) (PubMed).
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Interleukin-17A inhibits adipocyte differentiation in human mesenchymal stem cells and regulates pro-inflammatory responses in adipocytes." dans: Biochemical pharmacology, Vol. 77, Issue 12, pp. 1835-44, (2009) (PubMed).
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- Antigène
- Interleukin 17a (IL17A) (Interleukin 17A (IL17A))
- Autre désignation
- IL-17A (IL17A Produits)
- Synonymes
- anticorps CTLA8, anticorps IL-17, anticorps IL-17A, anticorps IL17, anticorps Ctla-8, anticorps Ctla8, anticorps Il17, anticorps ChIL-17, anticorps IL-17F, anticorps IL17A, anticorps CTLA-8, anticorps interleukin 17A, anticorps IL17A, anticorps Il17a
- Sujet
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IL17-A (also known as Interleukin-17) is a proinflammatory cytokine produced by activated T cells. This cytokine regulates the activities of NF-kappaB and mitogen-activated protein kinases. This cytokine can stimulate the expression of IL6 and cyclooxygenase-2 (PTGS2/COX-2), as well as enhance the production of nitric oxide (NO). High levels of this cytokine are associated with several chronic inflammatory diseases including rheumatoid arthritis, psoriasis and multiple sclerosis. IL17-A is the founding member of a group of cytokines called the IL-17 family. IL17-A was originally identified as a transcript from a rodent T-cell hybridoma. To elicit its functions, IL17 binds to a type I cell surface receptor called IL17R of which there are at least three variants IL17RA, IL17RB, and IL17RC. Anti-IL-17 antibody is ideal for investigators involved in cytokines, growth factors, cancer, and immunology reseach.
Synonyms: Interleukin-17, and in rodents only: Cytotoxic T-lymphocyte-associated antigen 8 and CTLA-8 - ID gène
- 3605
- UniProt
- Q16552
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