ARPC2 anticorps (AA 1-250) (FITC)

N° du produit ABIN1045180

Détail du produit anti-ARPC2 anticorps (FITC)

Antigène: ARPC2 (Actin Related Protein 2/3 Complex, Subunit 2, 34kDa (ARPC2))

Épitope: AA 1-250

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp ARPC2 est conjugé à/à la FITC

Application: Western Blotting (WB), ELISA

Réactivité croisée: Humain

Purification: >95%, Protein G purified

Immunogène: Recombinant Human Actin-related protein 2/3 complex subunit 2 protein (1-250AA)

Isotype: IgG

Information d'application

Indications d'application: Not yet tested in other applications. Optimal working dilutions should be determined experimentally by the investigator.

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, PH 7.4

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Conseil sur la manipulation: Avoid freeze and thaw cycles. Product is photosensitive and should be protected from light.

Stock: -20 °C,-80 °C

Stockage commentaire: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Détails sur ARPC2

Antigène: ARPC2 (Actin Related Protein 2/3 Complex, Subunit 2, 34kDa (ARPC2))

Autre désignation: ARPC2 (ARPC2 Produits)

Synonymes: anticorps arc34, anticorps p34-arc, anticorps pnas-139, anticorps pro2446, anticorps Arpc2, anticorps Arc-p34, anticorps 2210023N03Rik, anticorps 34kDa, anticorps p34-Arc, anticorps fk84a07, anticorps wu:fa22f07, anticorps wu:fk84a07, anticorps zgc:77769, anticorps ARC34, anticorps PNAS-139, anticorps actin related protein 2/3 complex subunit 2, anticorps actin related protein 2/3 complex, subunit 2, 34kDa, anticorps actin related protein 2/3 complex, subunit 2, anticorps actin related protein 2/3 complex subunit 2 S homeolog, anticorps ARPC2, anticorps arpc2, anticorps Arpc2, anticorps arpc2.S

Sujet:

Background: Actin-binding component of the Arp2/3 complex, a multiprotein complex that mediates actin polymerization upon stimulation by nucleation-promoting factor (NPF) (PubMed:9230079). The Arp2/3 complex mediates the formation of branched actin networks in the cytoplasm, providing the force for cell motility (PubMed:9230079). Seems to contact the mother actin filament (PubMed:9230079). In addition to its role in the cytoplasmic cytoskeleton, the Arp2/3 complex also promotes actin polymerization in the nucleus, thereby regulating gene transcription and repair of damaged DNA (PubMed:29925947). The Arp2/3 complex promotes homologous recombination (HR) repair in response to DNA damage by promoting nuclear actin polymerization, leading to drive motility of double-strand breaks (DSBs) (PubMed:29925947).

Aliases: Actin related protein 2/3 complex subunit 2 34 kDa antibody, Actin related protein 2/3 complex subunit 2 antibody, Actin-related protein 2/3 complex subunit 2 antibody, ARC 34 antibody, ARC34 antibody, Arp2/3 complex 34 kDa subunit antibody, ARP2/3 protein compex subunit 34 antibody, ARPC 2 antibody, Arpc2 antibody, ARPC2_HUMAN antibody, p34 Arc antibody, p34-ARC antibody, p34Arc antibody, PNAS 139 antibody, PNAS139 antibody, PRO 2446 antibody, PRO2446 antibody

UniProt: O15144

Pathways: Signalisation RTK, Regulation of Actin Filament Polymerization