beta-2 Microglobulin anticorps

N° du produit ABIN1045266

Détail du produit anti-beta-2 Microglobulin anticorps

Antigène: beta-2 Microglobulin (B2M) (beta-2-Microglobulin (B2M))

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp beta-2 Microglobulin est non-conjugé

Application: ELISA, Immunohistochemistry (IHC)

Specificité: Specific for B2M denatured and native forms

Réactivité croisée: Humain

Purification: Protein G purified

Pureté: > 95 %

Immunogène: Recombinant human Beta-2-microglobulin protein

Clone: 2D3E5

Isotype: IgG1, IgG1 kappa

Information d'application

Indications d'application: Recommended dilution:IHC:1:50-1:500,

Commentaires:

Other species are not tested. Please decide the specificity by homology

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, PH 7.4

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Conseil sur la manipulation: Avoid freeze and thaw cycles.

Stock: -20 °C,-80 °C

Stockage commentaire: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Références pour anticorps anti-beta-2 Microglobulin (ABIN1045266)

Stefanović, Djukanović, Cukuranović, Bukvić, Ležaić, Marić, Ogrizovic, Jovanović, Vlahovic, Pešić, Djordjević: "Beta2-microglobulin and alpha1-microglobulin as markers of Balkan endemic nephropathy, a worldwide disease." dans: Renal failure, Vol. 33, Issue 2, pp. 176-83, (2011) (PubMed).

Sharifiaghdas, Kashi, Eshratkhah: "Evaluating percutaneous nephrolithotomy-induced kidney damage by measuring urinary concentrations of β2-microglobulin." dans: Urology journal, Vol. 8, Issue 4, pp. 277-82, (2011) (PubMed).

Johnston, Cassidy, OConnell, ORiordan, Gallagher, Maguire, Wynne, Cagney, Ryan, Conlon, McMorrow: "Identification of β2-microglobulin as a urinary biomarker for chronic allograft nephropathy using proteomic methods." dans: Proteomics. Clinical applications, Vol. 5, Issue 7-8, pp. 422-31, (2011) (PubMed).

Kals, Zagura, Serg, Kampus, Zilmer, Unt, Lieberg, Eha, Peetsalu, Zilmer: "β2-microglobulin, a novel biomarker of peripheral arterial disease, independently predicts aortic stiffness in these patients." dans: Scandinavian journal of clinical and laboratory investigation, Vol. 71, Issue 4, pp. 257-63, (2011) (PubMed).

Dieterle, Perentes, Cordier, Roth, Verdes, Grenet, Pantano, Moulin, Wahl, Mahl, End, Staedtler, Legay, Carl, Laurie, Chibout, Vonderscher, Maurer: "Urinary clusterin, cystatin C, beta2-microglobulin and total protein as markers to detect drug-induced kidney injury." dans: Nature biotechnology, Vol. 28, Issue 5, pp. 463-9, (2010) (PubMed).

Détails sur beta-2 Microglobulin

Antigène: beta-2 Microglobulin (B2M) (beta-2-Microglobulin (B2M))

Autre désignation: B2M (B2M Produits)

Synonymes: anticorps Ly-m11, anticorps beta2-m, anticorps beta2m, anticorps bwm, anticorps wu:fa94c05, anticorps wu:fb10a09, anticorps b2m-W01, anticorps b2m-W03, anticorps b2m-Z01, anticorps b2m-Z02, anticorps b2m-Z03, anticorps B2M, anticorps b2m, anticorps B2MG, anticorps wu:fb66f11, anticorps wu:fj01f08, anticorps zgc:64161, anticorps b-2-m, anticorps beta-2-microglobulin, anticorps beta-2 microglobulin, anticorps beta-2-microglobulin S homeolog, anticorps beta-2-microglobulin, like, anticorps B2M, anticorps B2m, anticorps b2m, anticorps b2m.S, anticorps b2ml

Sujet:

Background: Beta 2 Microglobulin non-covalently associates with the 44 kDa alpha chain to form the HLA Class I antigen complex. Human beta 2 Microglobulin associated with HLA Class I antigens are expressed on many types of cells including lymphocytes, thymocytes, monocytes, granulocytes, platelets, endothelial cells, and epithelial cells. It is absent on erythrocytes.

Aliases: B2M, CDABP0092, HDCMA22P

UniProt: P61769

Pathways: TCR Signaling, Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process