Pyruvate Kinase anticorps

N° du produit ABIN106387

Détail du produit anti-Pyruvate Kinase anticorps

Antigène: Pyruvate Kinase (PK)

Reactivité: Lapin

Hôte: Chèvre

Clonalité: Polyclonal

Conjugué: Cet anticorp Pyruvate Kinase est non-conjugé

Application: Western Blotting (WB), ELISA, Immunoprecipitation (IP), Conjugation (Con), Dot Blot (DB)

Attributs du produit: Concentration Definition: by Refractometry

Purification: This product was prepared from monospecific antiserum by a delipidation and defibrination. Assay by immunoelectrophoresis resulted in a single precipitin arc against purified and partially purified Pyruvate Kinase [Rabbit Muscle].

Immunogène: Pyruvate Kinase [Rabbit Muscle]
Immunogentype:Native

Information d'application

Indications d'application: Anti-PYRUVATE KINASE Antibody is suitable for immunoblotting (western or dot blot), ELISA, immunoprecipitation, conjugation and most immunological methods requiring high titer and specificity. Specific conditions should be optimized by user.

Commentaires:

This product is for research use only and is not intended for therapeutic or diagnostic applications. Please contact a technical service representative for more information.

Restrictions: For Research Use only

Stockage

Format: Lyophilized

Reconstitution: Restore with deionized water (or equivalent)

Concentration: 40 mg/mL

Buffer: 0.02 M Potassium Phosphate, 0.15 M Sodium Chloride, pH 7.2

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C

Références pour anticorps anti-Pyruvate Kinase (ABIN106387)

Shimada, Shinagawa, Ishii: "Modulation of M2-type pyruvate kinase activity by the cytoplasmic PML tumor suppressor protein." dans: Genes to cells : devoted to molecular & cellular mechanisms, Vol. 13, Issue 3, pp. 245-54, (2008) (PubMed).

Détails sur Pyruvate Kinase

Antigène: Pyruvate Kinase (PK)

Autre désignation: Pyruvate Kinase (PK Produits)

Synonymes: anticorps CG7070, anticorps Dmel\\CG7070, anticorps PYK, anticorps Pyk, anticorps PYK3b, anticorps PYK3c, anticorps Pyruvate kinase, anticorps PK, anticorps pyruvate kinase, anticorps pyruvate kinase (PK), anticorps Pyruvate kinase (PK), anticorps pyruvate kinase PKM, anticorps testis expressed 45, anticorps PyK, anticorps pykA, anticorps PYK3a|PYK3b|PYK3c, anticorps pyk, anticorps pyk1, anticorps pk, anticorps LOC100534543, anticorps TEX45

Sujet: Pyruvate kinase (EC: 2.7.1.40) is an enzyme involved in glycolysis. It catalyzes the transfer of a phosphate group from phosphoenolpyruvate (PEP) to ADP, yielding one molecule of pyruvate and one molecule of ATP. This process also requires a magnesium ion. The enzyme is a 'transferase' under the international classification of enzymes. This step is the final one in the glycolytic pathway, which produces pyruvate molecules, the final product of aerobic glycolysis. However, in anaerobic glycolysis, lactate dehydrogenase will utilize the NADH produced by glyceraldehyde phosphate dehydrogenase to reduce pyruvate to lactate. In humans, there are two pyruvate kinase isozymes: type M (muscle, SwissProt P14618) and type L,R (liver and erythrocyte, SwissProt P30613). The isozymes differ in primary structure and regulation. This reaction has a large positive free energy change, one of three in glycolysis. All three such steps regulate the overall activity of the pathway, and are, in general, irreversible under wild-type conditions. Anti-Pyruvate kinase antibody is idea for investigators involved in cytokines and growth factor research.
Synonyms: Pyruvate kinase isozymes M1/M2 antibody, Pyruvate kinase muscle isozyme antibody, Pyruvate kinase 2/3 antibody, Cytosolic thyroid hormone-binding protein antibody

ID gène: 100008676

NCBI Accession: NP_001182574

UniProt: P11974