CITED2 anticorps (N-Term)

N° du produit ABIN1077387

Détail du produit anti-CITED2 anticorps

Antigène: CITED2 (Cbp/p300-Interacting Transactivator, with Glu/Asp-Rich Carboxy-terminal Domain, 2 (CITED2))

Épitope: N-Term

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp CITED2 est non-conjugé

Application: Western Blotting (WB), ELISA, Immunofluorescence (IF)

Specificité: Multiple isoforms of CITED2 are known to exist.

Purification: Affinity chromatography purified via peptide column

Immunogène: CITED2 antibody was raised against an 18 amino acid synthetic peptide near the amino terminus of human CITED2.

Isotype: IgG

Information d'application

Indications d'application: CITED2 antibody can be used for detection of CITED2 by Western blot at 1 - 2 μg/mL. For immunofluorescence start at 20 μg/mL.

Commentaires:

(NT) Cbp/p300-interacting transactivator 2

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: PBS containing 0.02 % Sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Stock: 4 °C

Stockage commentaire: CITED2 antibody can be stored at 4 °C for three months. At -20 °C stable for up to one year.

Date de péremption: 12 months

Détails sur CITED2

Antigène: CITED2 (Cbp/p300-Interacting Transactivator, with Glu/Asp-Rich Carboxy-terminal Domain, 2 (CITED2))

Autre désignation: CITED2 (CITED2 Produits)

Synonymes: anticorps mrg1, anticorps p35srj, anticorps zgc:103418, anticorps CITED2, anticorps cite2, anticorps ASD8, anticorps MRG-1, anticorps MRG1, anticorps P35SRJ, anticorps VSD2, anticorps AI835299, anticorps ER154-like, anticorps Mrg1, anticorps Msg2, anticorps Cbp/p300-interacting transactivator, with Glu/Asp rich carboxy-terminal domain, 2, anticorps Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 2, anticorps Cbp/p300 interacting transactivator with Glu/Asp rich carboxy-terminal domain 2, anticorps Cbp/p300-interacting transactivator 2, anticorps Cbp/p300-interacting transactivator, with Glu/Asp rich carboxy-terminal domain, 2 L homeolog, anticorps cited2, anticorps CITED2, anticorps cite2, anticorps Cited2, anticorps cited2.L

Sujet: CITED2 was initially identified as a potential transcriptional activator with significant homology to MSG1, a melanocyte-specific nuclear protein. CITED2 interacts with the histone acetyltransferase p300/CBP and acts as a coactivator to several DNA-binding transcription factors such as HIF-1 and AP-2. CITED2 also controls proliferation of mouse embryonic fibroblasts via the polycomb group genes Bmi-1 and Mel18 and the tumor suppressor Ink4a/Arf. CITED2 has also been found to be an essential regulator of adult hematopoietic stem cells (HSCs), with conditional deletion of CITED2 in the adult mouse resulting in the loss of HSCs, multilineage bone marrow failure and increased lethality.
Synonyms: Cbp/p300-interacting transactivator 2, melanocyte-specific gene 1-related gene 1, MSG-related protein 1, MRG1, melanocyte specific gene 2, MSG2, ER154-like, ASD8, VSD2

Poids moléculaire: 30 kDa

ID gène: 10370

NCBI Accession: NP_001161861

Pathways: Tube Formation