AGR2 anticorps (N-Term)

N° du produit ABIN1077447

Détail du produit anti-AGR2 anticorps

Antigène: AGR2 (Anterior Gradient Homolog 2 (Xenopus Laevis) (AGR2))

Épitope: N-Term

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp AGR2 est non-conjugé

Application: Western Blotting (WB), ELISA

Specificité: Two isoforms of AGR2 exists as a result of alternative splicing event.

Purification: Affinity chromatography purified via peptide column

Immunogène: Rabbit polyclonal AGR2 antibody was raised against a 17 amino acid peptide near the amino terminus of human AGR2.

Isotype: IgG

Information d'application

Indications d'application: AGR2 antibody can be used for detection of AGR2 by Western blot at 1 - 2 μg/mL.

Commentaires:

(NT) Anterior gradient 2 homolog

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: PBS containing 0.02 % Sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Stock: 4 °C

Stockage commentaire: Antibody can be stored at 4 °C for three months. At -20 °C stable for up to one year.

Date de péremption: 12 months

Détails sur AGR2

Antigène: AGR2 (Anterior Gradient Homolog 2 (Xenopus Laevis) (AGR2))

Autre désignation: AGR2 (AGR2 Produits)

Synonymes: anticorps AG2, anticorps GOB-4, anticorps HAG-2, anticorps PDIA17, anticorps XAG-2, anticorps Agr2h, anticorps Gob-4, anticorps mAG-2, anticorps wu:fj29g05, anticorps zgc:112187, anticorps agr2, anticorps hag3, anticorps hag-3, anticorps bcmp11, anticorps MGC89004, anticorps XAgr2, anticorps agr2-A, anticorps anterior gradient 2, protein disulphide isomerase family member, anticorps anterior gradient 2, anticorps anterior gradient 3, protein disulphide isomerase family member, anticorps anterior gradient 2, protein disulphide isomerase family member S homeolog, anticorps AGR2, anticorps Agr2, anticorps agr2, anticorps agr3, anticorps agr2.S

Sujet: AGR2 (anterior gradient protein 2) and AGR3 are members of the anterior gradient homolog family. They are secreted cytoplasmic proteins which are involved in metastasis induction and p53 tumour supressor inhibition. They may serve as molecular markers and potential therapeutic targets for hormone-responsive breast tumours. AGR2 is ubiquitously expressed with upregulated expression in prostate cancer, breast cancer, lung cancer, renal carcinomas and endometrial carcinomas. AGR2 expression is positively correlated with that of the estrogen receptor (ER) and is negatively correlated with that of the epidermal growth factor receptor (EGFR).
Synonyms: Anterior gradient 2 homolog, AG2, GOB-4, HAG-2, XAG-2, secreted cement gland homolog

Poids moléculaire: 19 kDa

ID gène: 10551

NCBI Accession: NP_006399