ABI1 anticorps (C-Term)
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- Antigène Voir toutes ABI1 Anticorps
- ABI1 (Abl-Interactor 1 (ABI1))
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Épitope
- C-Term
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Reactivité
- Humain, Rat, Souris
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Hôte
- Lapin
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Clonalité
- Polyclonal
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Conjugué
- Cet anticorp ABI1 est non-conjugé
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Application
- Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunofluorescence (IF), Immunohistochemistry (Frozen Sections) (IHC (fro))
- Specificité
- This antibody detects ABI1 / SSH3BP1 (C-term).
- Réactivité croisée (Details)
- Species reactivity (tested):Human, mouse, rat
- Purification
- Immunogen affinity purified
- Immunogène
- A synthetic peptide corresponding to a sequence at the C-terminal of human ABI-1 .Remarks: Sequence is different from the related rat and mouse sequence by single amino acid
- Isotype
- IgG
- Top Product
- Discover our top product ABI1 Anticorps primaire
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- Indications d'application
- Optimal working dilution should be determined by the investigator.
- Restrictions
- For Research Use only
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- Reconstitution
- 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
- Buffer
- 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Thimerosal, 0.05 mg NaN3
- Agent conservateur
- Sodium azide, Thimerosal (Merthiolate)
- Précaution d'utilisation
- This product contains Sodium azide and Thimerosal (Merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
- Conseil sur la manipulation
- Avoid repeated freezing and thawing.
- Stock
- 4 °C/-20 °C
- Stockage commentaire
- Store at 2 - 8 °C for up to one month or (in aliquots) at -20 °C for longer.
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- Antigène
- ABI1 (Abl-Interactor 1 (ABI1))
- Autre désignation
- ABI1 / SSH3BP1 (ABI1 Produits)
- Synonymes
- anticorps ABI-1, anticorps ABLBP4, anticorps E3B1, anticorps NAP1BP, anticorps SSH3BP, anticorps SSH3BP1, anticorps NAP1, anticorps Ssh3bp1, anticorps E3b1, anticorps abi1, anticorps wu:fc66g09, anticorps wu:fk56a10, anticorps zgc:73174, anticorps MGC84356, anticorps ABI1, anticorps abi-1, anticorps e3b1, anticorps nap1bp, anticorps ssh3bp, anticorps ssh3bp1, anticorps wu:fe48a10, anticorps zgc:153534, anticorps DKFZp469P1319, anticorps abl interactor 1, anticorps abl-interactor 1, anticorps abl-interactor 1a, anticorps abl interactor 1 S homeolog, anticorps abl-interactor 1b, anticorps Abl-interactor 1, anticorps Abl interactor 1, anticorps ABI1, anticorps Abi1, anticorps abi1a, anticorps abi1.S, anticorps abi1, anticorps abi1b, anticorps Bm1_44660, anticorps LOAG_04356
- Sujet
- ABI1 is a human homolog of mouse Abl-interactor-1 (Abi1), mapped on 10p11.2. ABI1 participate in the transduction of signals from Ras to Rac by regulating Rac-specific guanine nucleotide exchange factor (GEF) activities. ABI1 dramatically promoted ABL1-mediated tyrosine phosphorylation of MENA,but not of other substrates. Abi-1 regulates c-Abl-mediated phosphorylation of Mena by interacting with both proteins.ABI1 plays a role in the leukemogenesis by translocating to MLL.Synonyms: Abelson interactor 1, Abi-1, Abl interactor 1, Abl-binding protein 4, AblBP4, Eps8 SH3 domain-binding protein, Nap1-binding protein, Spectrin SH3 domain-binding protein 1, Spectrin binding protein, e3B1
- ID gène
- 10006
- NCBI Accession
- NP_001012768
- UniProt
- Q8IZP0
- Pathways
- Signalisation RTK, Response to Water Deprivation, ER-Nucleus Signaling
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