Acetyl-CoA Carboxylase beta anticorps (Internal Region)

N° du produit ABIN1105210

Détail du produit anti-Acetyl-CoA Carboxylase beta anticorps

Antigène: Acetyl-CoA Carboxylase beta (ACACB)

Épitope: Internal Region

Reactivité: Humain

Hôte: Chèvre

Clonalité: Polyclonal

Conjugué: Cet anticorp Acetyl-CoA Carboxylase beta est non-conjugé

Application: Enzyme Immunoassay (EIA)

Séquence: C-QLGEPDLSDK DRKD

Specificité: This antibody recognizes ACACB

Réactivité croisée (Details): Species reactivity (tested):Human.

Purification: Affinity Chromatography

Immunogène: Synthetic Peptide (C-QLGEPDLSDKDRKD) from the internal region of Human ACACB (NP_001084.2). Genename: ACACB

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Concentration: 0.5 mg/mL

Buffer: Tris saline, pH ~7.3, 0.02 % Sodium Azide, 0.5 % BSA

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freezing and thawing.

Stock: 4 °C/-20 °C

Stockage commentaire: Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Détails sur Acetyl-CoA Carboxylase beta

Antigène: Acetyl-CoA Carboxylase beta (ACACB)

Autre désignation: Acetyl-CoA Carboxylase 2 (ACACB Produits)

Synonymes: anticorps F15C21.2, anticorps F15C21_2, anticorps acetyl-CoA carboxylase 2, anticorps ACC2, anticorps ACCB, anticorps HACC275, anticorps Acc2, anticorps AI597064, anticorps AW743042, anticorps Accb, anticorps acetyl-CoA carboxylase 2, anticorps acetyl-CoA carboxylase beta, anticorps acetyl-Coenzyme A carboxylase beta, anticorps ACC2, anticorps ACACB, anticorps Acacb

Sujet: Acetyl-CoA carboxylase (ACC) is a complex multifunctional enzyme system which catalyzes the carboxylation of acetyl-CoA to malonyl-CoA, the rate-limiting step in fatty acid synthesis. Exercise diminishes the activity of acetyl-CoA carboxylase in human muscle. ACC alpha (ACC1) is the rate-limiting enzyme in the biogenesis of long-chain fatty acids, and ACC beta (ACC2) is thought to control mitochondrial fatty acid oxidation. These two isoforms of ACC control the amount of fatty acids in the cells. ACC beta is thought to control fatty acid oxidation by means of the ability of malonyl-CoA to inhibit carnitine-palmitoyl-CoA transferase I, the rate-limiting step in fatty acid uptake and oxidation by mitochondria. The gene encoding ACC beta maps to human chromosome 12 and encodes a mitochondiral protein expressed in heart and skeletal muscle. The catalytic core of ACC beta is homologous to that of ACC alpha, except for an additional peptide of about 150 amino acids at the N-terminusSynonyms: ACACB, ACC2, ACCB

ID gène: 32

NCBI Accession: NP_001084

Pathways: AMPK Signaling, Ribonucleoside Biosynthetic Process