ADAMTS4 anticorps (C-Term)

N° du produit ABIN1105251

Détail du produit anti-ADAMTS4 anticorps

Antigène: ADAMTS4 (ADAM Metallopeptidase with Thrombospondin Type 1 Motif, 4 (ADAMTS4))

Épitope: C-Term

Reactivité: Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp ADAMTS4 est non-conjugé

Application: Western Blotting (WB)

Specificité: This antibody detects ADAMTS4 at C-term.

Réactivité croisée (Details): Species reactivity (tested):Mouse, rat

Purification: Immunogen affinity purified

Immunogène: A synthetic peptide corresponding to a sequence at the C-terminal of mouse ADAMTS4 .Remarks: Sequence is different to the related rat sequence by three amino acids.

Isotype: IgG

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Reconstitution: 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

Buffer: 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Thimerosal, 0.05 mg NaN3

Agent conservateur: Sodium azide, Thimerosal (Merthiolate)

Précaution d'utilisation: This product contains Sodium azide and Thimerosal (Merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freezing and thawing.

Stock: 4 °C/-20 °C

Stockage commentaire: Store at 2 - 8 °C for up to one month or (in aliquots) at -20 °C for longer.

Détails sur ADAMTS4

Antigène: ADAMTS4 (ADAM Metallopeptidase with Thrombospondin Type 1 Motif, 4 (ADAMTS4))

Autre désignation: ADAMTS4 (ADAMTS4 Produits)

Synonymes: anticorps 3830423K05, anticorps ADAM-TS4, anticorps ADAMTS-2, anticorps ADMP-1, anticorps mKIAA0688, anticorps ADAMTS-4, anticorps ADAMTS4, anticorps a disintegrin-like and metallopeptidase (reprolysin type) with thrombospondin type 1 motif, 4, anticorps ADAM metallopeptidase with thrombospondin type 1 motif 4, anticorps ADAM metallopeptidase with thrombospondin type 1 motif, 4, anticorps Adamts4, anticorps ADAMTS4

Sujet: ADAM metallopeptidase with thrombospondin type 1 motif, 4, also known as ADAMTS4, is a human gene. This gene encodes a member of the ADAMTS (a disintegrin and metalloproteinase with thrombospondin motifs) protein family. ADAMTS is a novel family of extracellular proteases found in both mammals and invertebrates. Members of the family may be distinguished from the ADAM (adisintegrin and metalloprotease) family members based on the multiple copies of thrombospondin 1-like repeats they carry. Pratta et al. (2003) concluded that ADAMTS4 is constitutively produced in monolayer chondrocytes, capsular fibroblasts, and cartilage, and that stimulation by interleukin-1 results in aggrecanase activation. Thus, the activator could be a potential target by which to control aggrecanase-mediated degradation in arthritic diseases.Synonyms: A disintegrin and metalloproteinase with thrombospondin motifs 4, ADAM-TS4, ADAMTS-4, ADMP-1, ADMP1, Aggrecanase-1, KIAA0688

ID gène: 9507

NCBI Accession: NP_005090

UniProt: O75173