CD103 anticorps (PE)

N° du produit ABIN1105730

Détail du produit anti-CD103 anticorps (PE)

Antigène: CD103 (ITGAE) (Integrin, alpha E (Antigen CD103, Human Mucosal Lymphocyte Antigen 1, alpha Polypeptide) (ITGAE))

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp CD103 est conjugé à/à la PE

Application: Flow Cytometry (FACS)

Specificité: Clone B-ly7 recognizes an integrin containing the aE subunit which dimerizes with the b7 chain, present on hairy leukemia cells, to form the HML-1 (human mucosal lymphocyte) antigen. Clone B-ly7 is strongly reactive with hairy cell leukemia (HCL), activated monocytes, a subset of activated T and B cells (subtype of B cell chronic lymphocytic leukaemia), but not with other B cell leukemias or lymphomas. Testing by flow cytometry using a 'lyse-wash' method on a cell suspension containing HCL cells showed the following values expressed in terms of % of the total cell count: Product code: AM39027FC-N (anti-CD103 FITC) Mean % positive: 91,3 S.D.: 3,30 % CV: 3,61

Purification: Affinity chromatography

Clone: B-ly7

Isotype: IgG1

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Buffer: 0.01 M sodium phosphate, 0.15 M NaCl, pH 7.3, 0.2 % BSA, 0.09 % sodium azide

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C

Stockage commentaire: Store the antibody undiluted at 2-8 °C. Fluorochrome labelled product is photosensitive and should be protected from light.

Détails sur CD103

Antigène: CD103 (ITGAE) (Integrin, alpha E (Antigen CD103, Human Mucosal Lymphocyte Antigen 1, alpha Polypeptide) (ITGAE))

Autre désignation: CD103 (ITGAE Produits)

Synonymes: anticorps A530055J10, anticorps CD103, anticorps aM290, anticorps alpha-E1, anticorps alpha-M290, anticorps HUMINAE, anticorps integrin alpha E, epithelial-associated, anticorps integrin subunit alpha E, anticorps Itgae, anticorps ITGAE

Sujet: The function of the CD103 integrin is related to T cell interaction with epithelium and to T cell adhesion. CD103 is expressed primarily on intra-epithelial lymphocytes and on 1-2 % of peripheral blood lymphocytes. Cellular expression: Hairy Cell Leukemia (strong), subset activated T and B cells, activated monocytes.Synonyms: HML-1 antigen, ITGAE, Integrin alpha-E, Integrin alpha-IEL, Mucosal lymphocyte 1 antigen

ID gène: 2209

NCBI Accession: NP_000557

UniProt: P38570