MUC1 anticorps
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- Antigène Voir toutes MUC1 Anticorps
- MUC1 (Mucin 1 (MUC1))
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Reactivité
- Humain
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Hôte
- Souris
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Clonalité
- Monoclonal
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Conjugué
- Cet anticorp MUC1 est non-conjugé
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Application
- Western Blotting (WB), Immunofluorescence (IF), Flow Cytometry (FACS), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunoprecipitation (IP), Immunohistochemistry (Frozen Sections) (IHC (fro)), Enzyme Immunoassay (EIA), Immunoelectron Microscopy (IEM)
- Specificité
- This Mouse monoclonal antibody has been raised against Human milk-fat globule membranes (HMFGM) to obtain reagents for mammary tumor diagnosis. This monoclonal reacts towards an peptide epitope in the repeat region of MUC-1.
- Réactivité croisée (Details)
- Species reactivity (tested):Human.
- Purification
- Purified
- Immunogène
- Deglycosylated purified MUC1 glycoprotein.
- Clone
- 139H2
- Isotype
- IgG1
- Top Product
- Discover our top product MUC1 Anticorps primaire
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- Indications d'application
- Optimal working dilution should be determined by the investigator.
- Restrictions
- For Research Use only
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- Concentration
- 0.1 mg/mL
- Buffer
- PBS, 0.09 % Sodium Azide
- Agent conservateur
- Sodium azide
- Précaution d'utilisation
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Conseil sur la manipulation
- Avoid repeated freezing and thawing.
- Stock
- 4 °C/-20 °C
- Stockage commentaire
- Store undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
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- Antigène
- MUC1 (Mucin 1 (MUC1))
- Autre désignation
- CD227 / Mucin-1 / MUC1 (MUC1 Produits)
- Synonymes
- anticorps CA 15-3, anticorps CD227, anticorps EMA, anticorps H23AG, anticorps KL-6, anticorps MAM6, anticorps MCKD1, anticorps MUC-1, anticorps MUC-1/SEC, anticorps MUC-1/X, anticorps MUC1/ZD, anticorps PEM, anticorps PEMT, anticorps PUM, anticorps Muc-1, anticorps mucin 1, cell surface associated, anticorps mucin 1, transmembrane, anticorps MUC1, anticorps Muc1
- Sujet
- Mucin 1, cell surface associated (MUC-1) or polymorphic epithelial mucin (PEM) is a mucin encoded by the MUC1 gene in humans. MUC-1 is a glycoprotein with extensive O-linked glycosylation of its extracellular domain. Mucins line the apical surface of epithelial cells in the lungs, stomach, intestines, eyes and several other organs. The protein serves a protective function by binding to pathogens and also functions in a cell signaling capacity. Overexpression, aberrant intracellular localization, and changes in glycosylation of this protein have been associated with colon, breast, ovarian, lung and pancreatic cancers.Synonyms: Breast carcinoma-associated antigen DF3, CA 15-3, Carcinoma-associated mucin, DF3, EMA, Episialin, H23AG, MUC-1, PEMT, PUM, Peanut-reactive urinary mucin, Polymorphic epithelial mucin, Tumor-associated epithelial membrane antigen, Tumor-associated mucin
- ID gène
- 4582
- NCBI Accession
- NP_001018016
- UniProt
- P15941
- Pathways
- Negative Regulation of intrinsic apoptotic Signaling
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