TNFRSF10A anticorps (PE)

N° du produit ABIN1106162

Détail du produit anti-TNFRSF10A anticorps (PE)

Antigène: TNFRSF10A (Tumor Necrosis Factor Receptor Superfamily, Member 10a (TNFRSF10A))

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp TNFRSF10A est conjugé à/à la PE

Application: Flow Cytometry (FACS)

Specificité: This antibody recognises CD261, a 43-46 kDa protein.

Purification: Ion Exchange Chromatography

Immunogène: Recombinant Human TRAIL R1/Fc chimera.

Clone: B-N36

Isotype: IgG1

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Format: Liquid

Reconstitution: Restore with 1.0 mL deionised water.

Buffer: Phosphate-buffered saline (PBS), 0.09 % Sodium Azide, 1 % BSA

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: DO NOT FREEZE!

Stock: 4 °C

Stockage commentaire: Store the antibody undiluted at 2-8 °C.

Détails sur TNFRSF10A

Antigène: TNFRSF10A (Tumor Necrosis Factor Receptor Superfamily, Member 10a (TNFRSF10A))

Autre désignation: CD261 / TRAILR1 (TNFRSF10A Produits)

Synonymes: anticorps APO2, anticorps CD261, anticorps DR4, anticorps TRAILR-1, anticorps TRAILR1, anticorps TNFRSF10A, anticorps TNF receptor superfamily member 10a, anticorps tumor necrosis factor receptor superfamily member 26, anticorps tumor necrosis factor receptor superfamily, member 10a, anticorps TNFRSF10A, anticorps LOC510798

Sujet: Apoptosis, or programmed cell death, occurs during normal cellular differentiation and development of multicellular organisms. Apoptosis is induced by certain cytokines including TNF and Fas ligand in the TNF family through their death domain containing receptors, TNFR1 and Fas. A novel death domain containing receptor was recently identified and designated DR4 (for death receptor 4)1. The ligand for this novel death receptor has been identified and termed TRAIL, which is a new member in the TNF family. DR4 is also called TRAIL receptor-1 (TRAIL-R1). DR4 is expressed in most of human tissues including spleen, peripheral blood leukocytes, small intestine and thymus. Like TNFR1, Fas and DR3, DR4 mediates apoptosis and NF-kB activation in many tissues and cells.Synonyms: APO2, DR4, Death receptor 4, TNF-related apoptosis-inducing ligand receptor 1, TNFRSF10A, TRAIL receptor 1, TRAIL-R1, Tumor necrosis factor receptor superfamily member 10A

ID gène: 8797

NCBI Accession: NP_003835

UniProt: O00220

Pathways: Apoptose, Positive Regulation of Endopeptidase Activity