FAS anticorps (Fas (TNF Receptor Superfamily, Member 6))

Details for Product anti-FAS Antibody No. ABIN1106616
Antigène
  • ALPS1A
  • APO-1
  • APT1
  • CD95
  • FAS1
  • FASTM
  • TNFRSF6
  • FASL
  • TNFSF6
  • AI196731
  • APO1
  • TNFR6
  • Tnfrsf6
  • lpr
  • Fas cell surface death receptor
  • Fas ligand
  • tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein zeta
  • Fas (TNF receptor superfamily member 6)
  • FAS
  • FASLG
  • YWHAZ
  • Fas
  • fas
Reactivité
Humain
612
102
89
4
3
2
1
1
1
Hôte
Souris
362
316
7
4
4
3
Clonalité (Clone)
Monoclonal ()
Conjugué
Cet anticorp FAS est non-conjugé
66
56
42
28
16
9
8
8
7
7
7
7
4
4
4
4
4
2
2
2
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
Application
Enzyme Immunoassay (EIA), Flow Cytometry (FACS), Immunofluorescence (IF), Western Blotting (WB)
295
289
193
146
81
72
72
61
52
38
18
16
9
8
6
4
4
4
3
3
3
2
2
2
1
1
Options
Clone 4F8H6
Isotype IgG1
Specificité Recognizes CD95 / FAS
Réactivité croisée (Details) Species reactivity (tested):Human.
Purification Purified
Plasmids, Primers & others Plasmids, Primers & others FAS products on genomics-online (e.g. as negative or positive controls)
Antigène
Autre désignation CD95 / FAS (FAS Antibody Extrait)
Sujet Fas (APO-1, CD95) is a 45 kDa cell surface protein that mediates apoptosis when crosslinked with agonistic anti-Fas antibodies or Fas ligand (FasL). FasL is a tumor necrosis factor (TNF)-related type II membrane protein and is expressed in various tissue and cells. Both Fas and FasL are thought to play an important role in the apoptosis processes that takes place during T cell development.Synonyms: APT1, Apo-1 antigen, FAS1, FASLG receptor, TNFRSF6, Tumor necrosis factor receptor superfamily member 6
Poids moléculaire 37.7 kDa
ID gène 355
Pathways Signalisation p53, Apoptose, Production of Molecular Mediator of Immune Response, Positive Regulation of Endopeptidase Activity
Indications d'application Optimal working dilution should be determined by the investigator.
Restrictions For Research Use only
Format Liquid
Concentration 1.0 mg/mL
Buffer PBS, 0.05 % Sodium Azide, 0.5 % protein stabilizer
Agent conservateur Sodium azide
Précaution d'utilisation This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Images (Fournisseur)
Image no. 1 for anti-Fas (TNF Receptor Superfamily, Member 6) (FAS) antibody (ABIN1106616) anti-Fas (TNF Receptor Superfamily, Member 6) (FAS) antibody (Image 1)
Image no. 2 for anti-Fas (TNF Receptor Superfamily, Member 6) (FAS) antibody (ABIN1106616) anti-Fas (TNF Receptor Superfamily, Member 6) (FAS) antibody (Image 2)
Image no. 3 for anti-Fas (TNF Receptor Superfamily, Member 6) (FAS) antibody (ABIN1106616) anti-Fas (TNF Receptor Superfamily, Member 6) (FAS) antibody (Image 3)
Image no. 4 for anti-Fas (TNF Receptor Superfamily, Member 6) (FAS) antibody (ABIN1106616) anti-Fas (TNF Receptor Superfamily, Member 6) (FAS) antibody (Image 4)
Image no. 5 for anti-Fas (TNF Receptor Superfamily, Member 6) (FAS) antibody (ABIN1106616) anti-Fas (TNF Receptor Superfamily, Member 6) (FAS) antibody (Image 5)
Background publications Liu, Jung, Orlandi, Yeh, Lin, Shiu, Wu, Chu, Lin, Chu: "The Fas-mediated apoptotic pathway in cardiac myxoma." dans: International journal of surgical pathology, Vol. 18, Issue 6, pp. 493-8, 2010 (PubMed).

Talmud, Drenos, Shah, Shah, Palmen, Verzilli, Gaunt, Pallas, Lovering, Li, Casas, Sofat, Kumari, Rodriguez, Johnson, Newhouse, Dominiczak, Samani, Caulfield, Sever, Stanton, Shields, Padmanabhan et al.: "Gene-centric association signals for lipids and apolipoproteins identified via the HumanCVD BeadChip. ..." dans: American journal of human genetics, Vol. 85, Issue 5, pp. 628-42, 2009 (PubMed).

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