MBP anticorps (N-Term)

N° du produit ABIN110680

Détail du produit anti-MBP anticorps

Antigène: MBP (Myelin Basic Protein (MBP))

Épitope: AA 1-118, AA 45-91, N-Term

Reactivité: Humain, Boeuf (Vache), Porc, Lapin, Cobaye, Mouton

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp MBP est non-conjugé

Application: Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Enzyme Immunoassay (EIA), Radioimmunoassay (RIA)

Specificité: Recognises predominantly residues 45-91.

Réactivité croisée (Details): Species reactivity (expected):Guinea Pig, Rabbit, Porcine, Bovine, Sheep.
Species reactivity (tested):Human.

Purification: Protein A chromatography

Immunogène: Synthetic peptide corresponding to the amino acids 45-91 of the native molecule conjugated to Bovine Serum Albumin. N-terminal fragment of human MBP (residues 1-118) produced by BNPS-skatole cleavage of pure Human MBP, injected coupled to BSA using carbodiimide.

Clone: V-h5

Isotype: IgG1

Information d'application

Indications d'application: ELISA. Radioimmunoassays. Immunohistochemistry on Paraffin Sections (10 μg/mL).
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Stockage

Concentration: 1.0 mg/mL

Buffer: PBS buffer, pH 7.2 containing 0.09 % Sodium Azide as preservative.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freezing and thawing.

Stock: 4 °C/-20 °C

Stockage commentaire: Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Détails sur MBP

Antigène: MBP (Myelin Basic Protein (MBP))

Autre désignation: Myelin Basic Protein (MBP Produits)

Synonymes: anticorps C76307, anticorps Hmbpr, anticorps R75289, anticorps golli-mbp, anticorps mld, anticorps shi, anticorps Mbps, anticorps cb274, anticorps fj33b11, anticorps mbp, anticorps wu:fj33b11, anticorps wu:fq15b02, anticorps zgc:136630, anticorps MGC115135, anticorps myelin basic protein, anticorps myelin basic protein a, anticorps myelin basic protein L homeolog, anticorps MBP, anticorps Mbp, anticorps mbpa, anticorps mbp, anticorps mbp.L

Sujet: The classic group of Myelin basic protein (MBP) isoforms (isoforms 4 to 14) are with PLP the most abundant protein components of the myelin membrane in the CNS. They have a role in both its formation and stabilization. The smaller isoforms might have an important role in remyelination of denuded axons in multiple sclerosis. The non classic group of MBP isoforms (isoforms 1 to 3/Golli MBPs) may preferentially have a role in the early developing brain long before myelination, maybe as components of transcriptional complexes, and may also be involved in signaling pathways in T cells and neural cells. Differential splicing events combined to optional posttranslational modifications give a wide spectrum of isomers, each of them having maybe a specialized function.Synonyms: MBP, Myelin membrane encephalitogenic protein

ID gène: 4155

NCBI Accession: NP_001020252

UniProt: P02686