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PTGS1 anticorps (N-Term)

PTGS1 Reactivité: Humain, Souris, Rat WB, IHC (p) Hôte: Lapin Polyclonal unconjugated
N° du produit ABIN1106880
  • Antigène Voir toutes PTGS1 Anticorps
    PTGS1 (Prostaglandin-Endoperoxide Synthase 1 (Prostaglandin G/H Synthase and Cyclooxygenase) (PTGS1))
    Épitope
    • 15
    • 7
    • 5
    • 4
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    N-Term
    Reactivité
    • 67
    • 43
    • 25
    • 13
    • 5
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    Humain, Souris, Rat
    Hôte
    • 64
    • 11
    • 2
    Lapin
    Clonalité
    • 57
    • 20
    Polyclonal
    Conjugué
    • 49
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Cet anticorp PTGS1 est non-conjugé
    Application
    • 63
    • 24
    • 20
    • 14
    • 14
    • 13
    • 11
    • 9
    • 9
    • 6
    • 5
    • 4
    • 2
    • 1
    Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
    Specificité
    This antibody detects Cyclooxygenase 1 near N-term. No cross reactivity with other proteins.
    Réactivité croisée (Details)
    Species reactivity (tested):Human, mouse, rat
    Purification
    Immunogen affinity purified
    Immunogène
    Synthetic peptide corresponding to a sequence near the N-terminal of human PTGS1(COX1) .Remarks: Sequence different to the related rat and mouse sequence by two amino acids.
    Isotype
    IgG
    Top Product
    Discover our top product PTGS1 Anticorps primaire
  • Indications d'application
    Optimal working dilution should be determined by the investigator.
    Restrictions
    For Research Use only
  • Reconstitution
    0.2 mL of distilled water will yield a concentration of 500 μg/mL.
    Buffer
    5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Thimerosal, 0.05 mg NaN3
    Agent conservateur
    Sodium azide, Thimerosal (Merthiolate)
    Précaution d'utilisation
    This product contains Sodium azide and Thimerosal (Merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
    Conseil sur la manipulation
    Avoid repeated freezing and thawing.
    Stock
    4 °C/-20 °C
    Stockage commentaire
    Store at 2 - 8 °C for up to one month or (in aliquots) at -20 °C for longer.
  • Antigène
    PTGS1 (Prostaglandin-Endoperoxide Synthase 1 (Prostaglandin G/H Synthase and Cyclooxygenase) (PTGS1))
    Autre désignation
    Cyclooxygenase 1 (PTGS1 Produits)
    Synonymes
    anticorps COX-1, anticorps cox-1, anticorps PTGS1, anticorps Ptgs1, anticorps COX1, anticorps Cox-1, anticorps Cox-3, anticorps PGHS-1, anticorps PHS 1, anticorps Pghs1, anticorps Cox1, anticorps Cox3, anticorps cox1, anticorps zCOX-1, anticorps COX3, anticorps PCOX1, anticorps PES-1, anticorps PGG/HS, anticorps PGHS1, anticorps PHS1, anticorps PTGHS, anticorps COX-3, anticorps prostaglandin-endoperoxide synthase 1, anticorps cyclooxygenase-1, anticorps prostaglandin-endoperoxide synthase 1 (prostaglandin G/H synthase and cyclooxygenase), anticorps prostaglandin-endoperoxide synthase 1 S homeolog, anticorps PTGS1, anticorps cox-1, anticorps Ptgs1, anticorps ptgs1, anticorps ptgs1.S
    Sujet
    Cyclooxygenase 1 (COX1), also known as Prostaglandin-endoperoxide synthase (PTGS1), is the key enzyme in prostaglandin biosynthesis. The gene was approximately 40 kb long, with 11 protein-coding exons. There were 599 amino acid residues with a calculated molecular mass of approximately 68 kD.By analysis of a human/hamster somatic hybrid DNA panel, Funk et al. (1991) demonstrated that the PTGS1 gene maps to chromosome 9. Human prostaglandin endoperoxide synthase exhibited 91 % amino acid identity with the sheep enzyme. Prostaglandin synthase 1 gene disruption in mice reduces arachidonic acid-induced inflammation and indomethacin-induced gastric ulceration.Synonyms: COX-1, COX1, Cyclooxygenase-1, PGH synthase 1, PGHS-1, PTGS1, Prostaglandin G/H synthase 1, Prostaglandin H2 synthase 1, Prostaglandin-endoperoxide synthase 1
    ID gène
    5742
    NCBI Accession
    NP_000953
    UniProt
    P23219
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