EDNRB anticorps (Middle Region)

N° du produit ABIN1107094

Détail du produit anti-EDNRB anticorps

Antigène: EDNRB (Endothelin Receptor Type B (EDNRB))

Épitope: AA 244-258, Middle Region

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp EDNRB est non-conjugé

Application: Western Blotting (WB)

Specificité: This antibody detects Endothelin B Receptor. No cross reactivity with other proteins.

Réactivité croisée (Details): Species reactivity (tested):Human.

Purification: Immunogen Affinity Chromatography

Immunogène: A synthetic peptide corresponding to a sequence in the middle region of Human EDNR-B (244-258aa).

Isotype: IgG

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Reconstitution: 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

Buffer: 5 mg BSA, 0.9 mg Nacl, 0.2 mg Na2HPO4, 0.05 mg Thimerosal and 0.05 mg Sodium Azide

Agent conservateur: Sodium azide, Thimerosal (Merthiolate)

Précaution d'utilisation: This product contains Sodium azide and Thimerosal (Merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freezing and thawing.

Stock: 4 °C/-20 °C

Stockage commentaire: Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Détails sur EDNRB

Antigène: EDNRB (Endothelin Receptor Type B (EDNRB))

Autre désignation: Endothelin B Receptor (EDNRB Produits)

Synonymes: anticorps ABCDS, anticorps ET-B, anticorps ET-BR, anticorps ETB, anticorps ETBR, anticorps ETRB, anticorps HSCR, anticorps HSCR2, anticorps WS4A, anticorps Ednra, anticorps Etb, anticorps ETR-b, anticorps ETb, anticorps Sox10m1, anticorps EDNRB, anticorps abcds, anticorps etb, anticorps etrb, anticorps hscr, anticorps hscr2, anticorps endothelin receptor type B, anticorps EDNRB, anticorps Ednrb, anticorps ednrb

Sujet: Endothelin Receptor B (EDNR-B), also called endothelin receptor, nonselective type (ETB, ETRB). It is a G-protein-coupled receptor with seven transmembrane domains which is required for the development of melanocytes and enteric neurons and migration of melanoblasts and enteric neuroblasts. The EDNRB gene spans 24 kilobases and consists of seven exons and six introns.This gene was expressed in human glaucomatous optic nerves and mapped to 13q22. The cDNA fragment for horse EDNRB contained a 1329 bp open reading frame which encoded 443 amino acid residues. The predicted amino acid sequence was 89, 91 and 85 % identical to human, bovine and mouse as well as rat EDNRB respectively, but only 55 % identical to the human, bovine and rat endothelin A receptor (EDNRA). EDNRB plays an essential role in the normal development of two neural crest-derived cell lineages, epidermal melanocytes and enteric neurons in three mammalian species--humans, mice, and rats. The EDNRB-deficient rat may also prove valuable in defining the postnatal physiologic role of this receptor.Synonyms: ABCDS, EDNRB, ET-B, ET-BR, ETB, ETBR, ETRB, Endothelin receptor non-selective type, HSCR, HSCR2, WS4A, endothelin receptor type B

ID gène: 1910

NCBI Accession: NP_000106

UniProt: P24530

Pathways: Cellular Response to Molecule of Bacterial Origin, cAMP Metabolic Process