IFNA2 anticorps

N° du produit ABIN1107640

Détail du produit anti-IFNA2 anticorps

Antigène: IFNA2 (Interferon, alpha 2 (IFNA2))

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp IFNA2 est non-conjugé

Application: Western Blotting (WB), Enzyme Immunoassay (EIA), Functional Studies (Func), Neutralization (Neut)

Specificité: N27 is specific for INFalpha(II) and does not crossreact with INFalpha(I).

Réactivité croisée (Details): Species reactivity (tested):Human.

Purification: Purified

Immunogène: A BALB/c mouse was immunized with E-coli derived, purified recombinant IFN-alpha 2c and spleen cells were fused with mouse myeloma cells NS1.

Clone: N27

Isotype: IgG1

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Concentration: 0,1 mg/mL

Buffer: PBS, 0.05 % sodium azide

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C

Stockage commentaire: Store the antibody undiluted at 2-8 °C.

Détails sur IFNA2

Antigène: IFNA2 (Interferon, alpha 2 (IFNA2))

Autre désignation: IFNA2 / Interferon alpha-2 (IFNA2 Produits)

Synonymes: anticorps IFN-alphaA, anticorps IFNA, anticorps IFNA2B, anticorps INFA2, anticorps Ifa2, anticorps IFNA2, anticorps interferon alpha 2, anticorps interferon, alpha 2, anticorps interferon-alpha-2, anticorps interferon alpha-2, anticorps IFNA2, anticorps Ifna2, anticorps ifna2, anticorps IFN-ALPHA2, anticorps LOC102142148

Sujet: The alpha interferons are involved in virus resistance in target cells for these viruses. They are known to block cell proliferation and to regulate MHC class I antigen expression. The IFNalpha family has pseudogenes in two families (I and II), one with a mature length of 166aa and one of 172aa. Cells producing IFNalpha are lymphocytes, monocytes, macrophages and cell lines such as Namalwa and KGI. Bioassays for IFNalpha include cytopathic effect blocking, by viruses such as VSV, SFV and BMCV, on their target cells. A number of receptors for IFNalpha are now known and seem to be expressed on most cell types.Synonyms: IFN-alpha 2, Interferon alpha-A, LeIF A

ID gène: 3440

NCBI Accession: NP_000596

UniProt: P01563

Pathways: Signalistation JAK/STAT, Regulation of Leukocyte Mediated Immunity, Production of Molecular Mediator of Immune Response, Hepatitis C