Sca-1/Ly-6A/E anticorps

N° du produit ABIN1108075

Détail du produit anti-Sca-1/Ly-6A/E anticorps

Antigène: Sca-1/Ly-6A/E (Ly6a) (Lymphocyte Antigen 6 Complex, Locus A (Ly6a))

Reactivité: Souris

Hôte: Rat

Clonalité: Monoclonal

Conjugué: Cet anticorp Sca-1/Ly-6A/E est non-conjugé

Application: Flow Cytometry (FACS)

Specificité: This antibody reacts with Sca-1.

Réactivité croisée (Details): Species reactivity (tested):Mouse

Purification: Protein G agarose

Immunogène: Mouse Sca-1 transfected LO cells

Clone: 238B

Isotype: IgG2a

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Buffer: PBS containing 50 % glycerol, pH 7.2. No preservative is contained.

Agent conservateur: Without preservative

Conseil sur la manipulation: Avoid repeated freezing and thawing.

Stock: -20 °C

Stockage commentaire: Store (in aliquots) at -20 °C.

Détails sur Sca-1/Ly-6A/E

Antigène: Sca-1/Ly-6A/E (Ly6a) (Lymphocyte Antigen 6 Complex, Locus A (Ly6a))

Autre désignation: Ly6A/E / SCA1 (Ly6a Produits)

Synonymes: anticorps Ly-6A.2, anticorps Ly-6A/E, anticorps Ly-6E.1, anticorps Sca-1, anticorps Sca1, anticorps TAP, anticorps lymphocyte antigen 6 complex, locus A, anticorps Ly6a

Sujet: Sca-1 is a member of the Ly-6 antigen family which molecular mass of 8 kDa under nonreducing conditions and of 18 kDa under reducing conditions. Mouse hematopoietic stem cell expresses low levels of Thy-1 antigen (Thy-1lo) and to be lineage-negative (Lin-), not express markers characteristic of B cells (B220), granulocytes (Gr-1), myelomonocytic cells (Mac-1) and T lymphocytes (CD4 and CD8). Recently, new monoclonal antibody, anti-Sca-1, was used to purify stem cells from the Thy-1lo, Lin- bone marrow subpopulation. Thy-1lo, Lin-, Sca-1+ (but not the Thy-1lo, Lin-, Sca-1-) population of bone marrow cells are highly purified pluripotent stem cells. They read out with nearly unit efficiency in assays for primitive myeloerythroid and thymic progenitor, and have a capability to admit lethally irradiated mouse to survive and be restored in all blood-cell lineages. The Thy-1lo, Lin-, Sca-1+ subpopulation thought to have all stem cells present in the bone marrow.Synonyms: Ly-6A.2/Ly-6E.1, Lymphocyte antigen 6A-2/6E-1, SCA-1, Stem cell antigen 1, T-cell-activating protein, TAP

ID gène: 110454

NCBI Accession: NP_034868

UniProt: P05533

Pathways: Sensory Perception of Sound, Activated T Cell Proliferation