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MCL-1 anticorps
MCL1
Reactivité: Humain
WB, IHC (p), EIA
Hôte: Souris
Monoclonal
8C6 (8C6D4B1)
unconjugated
N° du produit ABIN1108171
Détail du produit anti-MCL-1 anticorps
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Antigène
Voir toutes MCL-1 (MCL1) Anticorps
MCL-1 (MCL1)
(Induced Myeloid Leukemia Cell Differentiation Protein Mcl-1 (MCL1))
Reactivité
Toutes les réactivités sur MCL-1 Anticorps
Humain
Hôte
Toutes les hôtes sur MCL-1 Anticorps
Souris
Clonalité
Toutes les clonalités sur MCL-1 Anticorps
Monoclonal
Conjugué
Tous les conjugués à travers MCL-1 Anticorps
Cet anticorp MCL-1 est non-conjugé
Application
Tous les applications à travers MCL-1 Anticorps.
Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Enzyme Immunoassay (EIA)
Specificité
This monoclonal antibody detected a 37 kDa MCL1 in BCBL-1 cell lysate.
Réactivité croisée (Details)
Species reactivity (tested):Human.
Purification
Purified
Clone
8C6 (8C6D4B1)
Isotype
IgG1
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Discover our top product MCL1 Anticorps primaire
Alternatives
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Information d'application
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Indications d'application
Optimal working dilution should be determined by the investigator.
Restrictions
For Research Use only
Stockage
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Buffer
PBS, 0.03 % Sodium Azide
Agent conservateur
Sodium azide
Précaution d'utilisation
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Détails sur MCL-1
(cache)
Antigène
MCL-1 (MCL1)
(Induced Myeloid Leukemia Cell Differentiation Protein Mcl-1 (MCL1))
Autre désignation
MCL1 (MCL1 Produits )
Synonymes
anticorps BCL2L3, anticorps EAT, anticorps MCL1-ES, anticorps MCL1L, anticorps MCL1S, anticorps Mcl-1, anticorps TM, anticorps bcl2-L-3, anticorps mcl1/EAT, anticorps AW556805, anticorps mcl-1, anticorps fb72f02, anticorps wu:fb70a08, anticorps wu:fb72f02, anticorps zfMLP1, anticorps zfMcl-1a, anticorps zgc:109835, anticorps zgc:109763, anticorps E3, anticorps E3-2, anticorps RNE3, anticorps RNU107, anticorps SNORA63A, anticorps elF-4AII, anticorps MCL1, BCL2 family apoptosis regulator, anticorps myeloid cell leukemia sequence 1, anticorps MCL1, BCL2 family apoptosis regulator a, anticorps MCL1, BCL2 family apoptosis regulator b, anticorps small nucleolar RNA, H/ACA box 63, anticorps MCL1, anticorps Mcl1, anticorps mcl1a, anticorps mcl1b, anticorps SNORA63
Sujet
Mcl-1 (Myeloid cell leukemia-1) is Bcl-2-related and was identified as an early-induction gene thatincreased in expression during the differentiation of human myeloblastic leukemia cell ML-1, or exposure to different DNA damaging agents. The level of Mcl-1 is decreased in peripheral B lymphocytes undergoing apoptosis following treatment with apoptotic stimuli such as TGF-alpha 1 and forskolin. Expression of Mcl-1 is able to delay apoptosis induced by over-expression of c-myc in CHO 5AHSmyc cells. In hematopoietic FDC-P1 cells, Mcl-1 interacts with another Bcl-2-related protein, Bax, and prolongs cell viability after treatment with different apoptotic reagents.Synonyms: BCL2L3, Bcl-2-like protein 3, Bcl-2-related protein, EAT, Induced myeloid leukemia cell differentiation protein Mcl-1, mcl1/EAT, r004
ID gène
4170
Pathways
Signalisation MAPK
Vus récemment
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