PSMC3 anticorps (Middle Region)

N° du produit ABIN1108775

Détail du produit anti-PSMC3 anticorps

Antigène: PSMC3 (Proteasome (Prosome, Macropain) 26S Subunit, ATPase, 3 (PSMC3))

Épitope: Middle Region

Reactivité: Humain, Souris, Rat, Xenopus laevis, Chien, Poisson zèbre (Danio rerio), Boeuf (Vache), Poulet

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp PSMC3 est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Séquence: TKRFDSEKAG DREVQRTMLE LLNQLDGFQP NTQVKVIAAT NRVDILD

Réactivité croisée (Details): Species reactivity (expected):Mouse, Dog, Rat, Chicken, Bovine, Zebrafish, African clawed frogSpecies reactivity (tested):Human

Purification: Purified using Protein A affinity column.

Immunogène: The immunogen for anti-PSMC3 antibody: synthetic peptide directed towards the middle region of human PSMC3.

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Reconstitution: Add 100 μL of distilled water to a final concentration of 1 mg/mL.

Conseil sur la manipulation: Avoid repeated freezing and thawing.

Stock: 4 °C/-20 °C

Stockage commentaire: Store lyophilized at 2-8 °C or at -20 °C long term. After reconstitution store the antibody undiluted at 2-8 °C for up to one month or in aliquots at -20 °C long term.

Détails sur PSMC3

Antigène: PSMC3 (Proteasome (Prosome, Macropain) 26S Subunit, ATPase, 3 (PSMC3))

Autre désignation: PSMC3 / TBP1 (PSMC3 Produits)

Synonymes: anticorps TBP1, anticorps TBP-1, anticorps wu:fb39a02, anticorps zgc:86713, anticorps psmc3, anticorps MGC89608, anticorps PSMC3, anticorps NV15940, anticorps 23.m06430, anticorps DDBDRAFT_0186002, anticorps DDBDRAFT_0232967, anticorps DDB_0186002, anticorps DDB_0232967, anticorps psmc3-b, anticorps tbp10, anticorps psmc3-a, anticorps proteasome 26S subunit, ATPase 3, anticorps proteasome (prosome, macropain) 26S subunit, ATPase 3, anticorps 26S protease regulatory subunit 6A, anticorps 26S protease regulatory subunit 6a, anticorps 26S protease regulatory subunit 6A-B, anticorps 26S protease regulatory subunit 6A, putative, anticorps proteasome 26S subunit, ATPase 3 S homeolog, anticorps nth-like DNA glycosylase 1 S homeolog, anticorps PSMC3, anticorps Psmc3, anticorps HCAG_00069, anticorps GL50803_4365, anticorps EDI_316920, anticorps CpipJ_CPIJ006888, anticorps CpipJ_CPIJ006889, anticorps CpipJ_CPIJ010864, anticorps prs6a, anticorps psmc3, anticorps LOC100115023, anticorps BBOV_IV004580, anticorps CGB_M2140W, anticorps psmC3, anticorps LOC100637883, anticorps psmc3.S, anticorps nthl1.S

Sujet: PSMC3 is a subunit of the 26S proteasome. 26S proteasome is a multicatalytic proteinase complex with a highly ordered structure composed of 2 complexes, a 20S core and a 19S regulator. The 20S core is composed of 4 rings of 28 non-identical subunits, 2 rings are composed of 7 alpha subunits and 2 rings are composed of 7 beta subunits. The 19S regulator is composed of a base, which contains 6 ATPase subunits and 2 non-ATPase subunits, and a lid, which contains up to 10 non-ATPase subunits. Proteasomes are distributed throughout eukaryotic cells at a high concentration and cleave peptides in an ATP/ubiquitin-dependent process in a non-lysosomal pathway. An essential function of a modified proteasome, the immunoproteasome, is the processing of class I MHC peptides. This gene encodes one of the ATPase subunits, a member of the triple-A family of ATPases which have a chaperone-like activity. This subunit may compete with PSMC2 for binding to the HIV tat protein to regulate the interaction between the viral protein and the transcription complex. A pseudogene has been identified on chromosome 9.Synonyms: 26S protease regulatory subunit 6A, Proteasome 26S subunit ATPase 3, Proteasome subunit P50, TBP-1, Tat-binding protein 1

ID gène: 5702

NCBI Accession: NP_002795

Pathways: Mitotic G1-G1/S Phases, DNA Replication, Synthesis of DNA, Ubiquitin Proteasome Pathway