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SMAD1 anticorps (C-Term)
SMAD1
Reactivité: Humain, Rat
WB
Hôte: Lapin
Polyclonal
unconjugated
N° du produit ABIN1109057
Détail du produit anti-SMAD1 anticorps
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Antigène
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SMAD1
(SMAD, Mothers Against DPP Homolog 1 (SMAD1))
Épitope
Tous les épitopes à travers SMAD1 Anticorps.
AA 442-456, C-Term
Reactivité
Toutes les réactivités sur SMAD1 Anticorps
Humain, Rat
Hôte
Toutes les hôtes sur SMAD1 Anticorps
Lapin
Clonalité
Toutes les clonalités sur SMAD1 Anticorps
Polyclonal
Conjugué
Tous les conjugués à travers SMAD1 Anticorps
Cet anticorp SMAD1 est non-conjugé
Application
Tous les applications à travers SMAD1 Anticorps.
Western Blotting (WB)
Specificité
This antibody detects SMAD1/2/3/5 (C-term, 442-456). No cross reactivity with other proteins.
Réactivité croisée (Details)
Species reactivity (tested):Human, rat
Purification
Immunogen affinity purified
Immunogène
A synthetic peptide corresponding to a sequence at the C-terminal of human Smad 1,2,3,5 (442-456aa), identical to the related rat sequence
Isotype
IgG
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Information d'application
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Indications d'application
Optimal working dilution should be determined by the investigator.
Restrictions
For Research Use only
Stockage
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Reconstitution
0.2 mL of distilled water will yield a concentration of 500 μg/mL.
Buffer
5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Thimerosal, 0.05 mg NaN3
Agent conservateur
Sodium azide, Thimerosal (Merthiolate)
Précaution d'utilisation
This product contains Sodium azide and Thimerosal (Merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
Conseil sur la manipulation
Avoid repeated freezing and thawing.
Stock
4 °C/-20 °C
Stockage commentaire
Store at 2 - 8 °C for up to one month or (in aliquots) at -20 °C for longer.
Détails sur SMAD1
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Antigène
SMAD1
(SMAD, Mothers Against DPP Homolog 1 (SMAD1))
Autre désignation
SMAD1 (SMAD1 Produits )
Synonymes
anticorps MLP, anticorps Xmad1, anticorps Xsmad1, anticorps bsp1, anticorps jv4-1, anticorps jv41, anticorps madh1, anticorps madr1, anticorps smad-1, anticorps MADH1, anticorps fb39h09, anticorps wu:fb39h09, anticorps wu:fb97e04, anticorps 2/23, anticorps CG12399, anticorps Dmel\\CG12399, anticorps E(zen)2, anticorps En(vvl), anticorps MAD, anticorps Mat, anticorps P-Mad, anticorps P-mad, anticorps PMad, anticorps Smad, anticorps Smad1, anticorps apg, anticorps c28, anticorps dMAD, anticorps dMad, anticorps l(2)K00237, anticorps l(2)k00237, anticorps mad, anticorps p-Mad, anticorps pMAD, anticorps pMad, anticorps pSmad, anticorps BSP-1, anticorps BSP1, anticorps JV4-1, anticorps JV41, anticorps MADR1, anticorps AI528653, anticorps Madh1, anticorps Madr1, anticorps Mlp1, anticorps MusMLP, anticorps smad1, anticorps xmad, anticorps SMAD family member 1, anticorps Mothers against dpp, anticorps SMAD family member 1 L homeolog, anticorps smad1, anticorps SMAD1, anticorps Mad, anticorps Smad1, anticorps smad1.L
Sujet
SMADs are proteins that modulate the activity of transforming growth factor beta ligands. The SMADs,often in complex with other SMADs/CoSMAD, act as transcription factors that regulate the expression of certain genes. Zhu, H et al concluded that targeted ubiquitination of SMADs may serve to control both embryonic development and a wide variety of cellular responses to TGF-beta signals. R-Smads or receptor regulated Smads are a class of proteins that include SMAD1, SMAD2, SMAD3, SMAD5, and SMAD8. In response to signals by the TGF-β superfamily of ligands these proteins associate with receptor kinases and are phosphorylated at an SSXS motif at their extreme C-terminus. These proteins then typically bind to the common mediator Smad or co-SMAD SMAD4.Synonyms: 2, 3, 5, SMAD1, SMAD2, SMAD3, SMAD5
ID gène
4086
NCBI Accession
NP_001003688
UniProt
Q15797
Pathways
Stem Cell Maintenance , Regulation of Muscle Cell Differentiation , Skeletal Muscle Fiber Development
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