TLE3 anticorps (N-Term)

N° du produit ABIN1109265

Détail du produit anti-TLE3 anticorps

Antigène: TLE3 (Transducin-Like Enhancer Protein 3 (TLE3))

Épitope: N-Term

Reactivité: Humain, Souris, Rat, Chien, Poisson zèbre (Danio rerio)

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp TLE3 est non-conjugé

Application: Western Blotting (WB)

Séquence: GSSSGLLALG ALGSQAHLTV KDEKNHHELD HRERESSANN SVSPSESLRA

Réactivité croisée (Details): Species reactivity (expected):Dog, Mouse, Rat, ZebrafishSpecies reactivity (tested):Human

Purification: Purified using Protein A affinity column

Immunogène: The immunogen for anti-TLE3 antibody: synthetic peptide directed towards the N terminal of human TLE3

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Reconstitution: Add 100 μL of distilled water to a final concentration of 1 mg/mL.

Conseil sur la manipulation: Avoid repeated freezing and thawing.

Stock: 4 °C/-20 °C

Stockage commentaire: Store lyophilized at 2-8 °C or at -20 °C long term. After reconstitution store the antibody undiluted at 2-8 °C for up to one month or in aliquots at -20 °C long term.

Détails sur TLE3

Antigène: TLE3 (Transducin-Like Enhancer Protein 3 (TLE3))

Autre désignation: TLE3 (TLE3 Produits)

Synonymes: anticorps TLE3, anticorps ESG, anticorps ESG1, anticorps Xesg1, anticorps esg2, anticorps esg3, anticorps grg2, anticorps grg3, anticorps hst18976, anticorps tle3, anticorps xgrg3, anticorps ESG3, anticorps GRG3, anticorps HsT18976, anticorps Esp3, anticorps 2610103N05Rik, anticorps Grg3a, anticorps Grg3b, anticorps mKIAA1547, anticorps transducin like enhancer of split 3, anticorps transducin like enhancer of split 2, anticorps transducin-like enhancer of split 3, anticorps TLE3, anticorps tle2, anticorps Tle3

Sujet: The TLE genes are differentially expressed and encode nuclear proteins, consistent with the presence of sequence motifs associated with nuclear functions. These genes are the human homologues of Drosophila groucho, a member of the Notch signaling pathway which controls a number of different cell-fate choices in invertebrates and vertebrates.TLE3 is a transcriptional corepressor that binds to a number of transcription factors. It inhibits the transcriptional activation mediated by CTNNB1 and TCF family members in Wnt signaling. The effects of full-length TLE family members may be modulated by association with dominant-negative AES.Synonyms: ESG3, GRG3, KIAA1547, Transducin-like enhancer protein 3

ID gène: 7090

NCBI Accession: NP_005069

Pathways: SARS-CoV-2 Protein Interactome