Insulin anticorps (INS)

Details for Product anti-INS Antibody No. ABIN111464, Fournisseur: Connectez-vous pour afficher
Antigène
  • ins1
  • xins
  • ins1-a
  • Insulin
  • IDDM2
  • ILPR
  • IRDN
  • MODY10
  • AA986540
  • Ins-2
  • InsII
  • Mody
  • Mody4
  • proinsulin
  • zgc:109842
  • insulin
  • insulin precursor
  • insulin II
  • preproinsulin
  • ins
  • PIN
  • INS
  • Ins
  • INS-IGF2
  • Ins2
Reactivité
Humain
955
463
374
347
246
189
45
11
9
8
7
7
6
3
3
2
2
2
2
2
1
1
1
1
1
1
1
Hôte
Souris
776
211
48
9
4
2
1
Clonalité (Clone)
Monoclonal ()
Conjugué
Cet anticorp Insulin est non-conjugé
52
40
36
21
20
20
19
15
15
14
13
13
13
13
13
13
13
10
9
9
7
7
7
5
5
5
5
5
5
5
5
5
5
5
5
5
5
5
5
5
5
5
2
1
Application
Enzyme Immunoassay (EIA), Immunohistochemistry (Frozen Sections) (IHC (fro)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
459
348
268
268
255
239
173
112
107
66
63
34
23
23
21
7
5
4
4
4
4
3
2
2
2
1
1
1
1
1
1
Options
Fournisseur
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N° du produit (Fournisseur)
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Immunogène Human C-peptide conjugated to BSA
Clone C-PEP-01
Isotype IgG1
Specificité This antibody recognises C-peptide (also known as connecting peptide) a peptide released when proinsulin is cleaved to produce insulin. It can also be used to detect proinsulin.
Réactivité croisée (Details) Also reacts to: Proinsulin
Purification Affinity chromatography on Protein A
Plasmids, Primers & others Plasmids, Primers & others Insulin products on genomics-online (e.g. as negative or positive controls)
Antigène
Autre désignation Insulin (INS Antibody Extrait)
Sujet Synonyms: INS
ID gène 3630
NCBI Accession NP_000198
UniProt P01308
Pathways Signalisation NF-kappaB, Signalisation RTK, Positive Regulation of Peptide Hormone Secretion, Peptide Hormone Metabolism, Hormone Activity, Carbohydrate Homeostasis, ER-Nucleus Signaling, Regulation of Carbohydrate Metabolic Process, Feeding Behaviour, Autophagy, Negative Regulation of intrinsic apoptotic Signaling, Brown Fat Cell Differentiation, Positive Regulation of fat Cell Differentiation
Indications d'application Immunohistochemistry on frozen sections.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.
Restrictions For Research Use only
Concentration 1.0 mg/mL
Buffer PBS, pH 7.2 containing 0.09 % sodium azide
Agent conservateur Sodium azide
Précaution d'utilisation This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Conseil sur la manipulation Avoid repeated freezing and thawing.
Stock 4 °C/-20 °C
Stockage commentaire Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
Produit citée dans: Meier, Köhler, Alkhatib, Sergi, Junker, Klein, Schmidt, Fritsch: "Beta-cell development and turnover during prenatal life in humans." dans: European journal of endocrinology / European Federation of Endocrine Societies, Vol. 162, Issue 3, pp. 559-68, 2010 (PubMed).

Background publications Hilgert, Stolba, Kristofová, Stefanová, Bendlová, Lebl, Horejsí: "A monoclonal antibody applicable for determination of C-peptide of human proinsulin by RIA." dans: Hybridoma, Vol. 10, Issue 3, pp. 379-86, 1991 (PubMed).

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