GDNF anticorps (Biotin)
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- Antigène Voir toutes GDNF Anticorps
- GDNF (Glial Cell Line Derived Neurotrophic Factor (GDNF))
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Reactivité
- Humain
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Hôte
- Lapin
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Clonalité
- Polyclonal
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Conjugué
- Cet anticorp GDNF est conjugé à/à la Biotin
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Application
- Western Blotting (WB), Immunohistochemistry (Frozen Sections) (IHC (fro)), Enzyme Immunoassay (EIA)
- Specificité
- Human Glial Derived Neurotrophic Factor.
- Purification
- Affinity chromatography.
- Immunogène
- Highly pure (>98%) recombinant hGDNF.
- Top Product
- Discover our top product GDNF Anticorps primaire
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- Indications d'application
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ELISA: To detect hGDNF by direct ELISA (using 100 ml/well antibody solution) this GDNFantibody can be used at a concentration of 0.15-0.30 μg/mL. Used in conjunction withcompatible secondary reagents, allows the detection of at least 0.2 ng/well of recombinanthGDNF. Western Blot: To detect hGDNF by Western Blot analysis this GDNF antibody can be used ata concentration of 0.1-0.2 mg/mL. Used in conjunction with compatible secondary reagentsthe detection limit for recombinant hGDNF is 1.5-3.0 ng/lane, under either reducing ornon-reducing conditions.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. - Restrictions
- For Research Use only
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- Reconstitution
- Restore in sterile PBS containing 0.1 % BSA to a concentration of 0.1-1.0 mg/mL.
- Buffer
- PBS, pH 7.2 without preservatives.
- Agent conservateur
- Without preservative
- Conseil sur la manipulation
- Centrifuge vial prior to opening! This product is photosensitive and should be protected from light
- Stock
- 4 °C
- Stockage commentaire
- Store the antibody at 2-8 °C. DO NOT FREEZE!
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- Antigène
- GDNF (Glial Cell Line Derived Neurotrophic Factor (GDNF))
- Autre désignation
- GDNF (GDNF Produits)
- Synonymes
- anticorps gdnf, anticorps GDNF, anticorps AI385739, anticorps gdnfa, anticorps hfb1-gdnf, anticorps ATF1, anticorps ATF2, anticorps HFB1-GDNF, anticorps HSCR3, anticorps glial cell derived neurotrophic factor, anticorps glial cell derived neurotrophic factor a, anticorps glial cell line derived neurotrophic factor, anticorps glial cell derived neurotrophic factor L homeolog, anticorps Gdnf, anticorps gdnfa, anticorps GDNF, anticorps gdnf.L
- Sujet
- Glial cell line derived neurotrophic factor (GDNF) is a highly conserved neurotrophic factor that is a distant member of the TGF beta superfamily. The GDNF gene product is processed to a disulphide-linked homodimer, which is a ligand for the RET protooncogene. GDNF protects and repairs dopamine-containing neurons, which degenerate in Parkinson's disease, and motor neurons, which die in amyotrophic lateral sclerosis. The use of GDNF in the treatment of Parkinson's disease has shown promise in the clinic. Treatment of spinal cord injuries with GDNF has also produced neurological improvement.Synonyms: ATF, Astrocyte-derived trophic factor, Glial cell line-derived neurotrophic factor
- ID gène
- 2668
- NCBI Accession
- NP_000505
- UniProt
- P39905
- Pathways
- Signalisation RTK, Synaptic Membrane, Tube Formation, Autophagy, Smooth Muscle Cell Migration
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