WIPF1 anticorps (pSer488) (Alexa Fluor 647)

N° du produit ABIN1177222

Détail du produit anti-WIPF1 anticorps (Alexa Fluor 647)

Antigène: WIPF1 (WAS/WASL Interacting Protein Family, Member 1 (WIPF1))

Épitope: pSer488

Reactivité: Humain, Souris, Rat

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp WIPF1 est conjugé à/à la Alexa Fluor 647

Application: Intracellular Staining (ICS)

Marque: BD Phosflow™

Purification: The monoclonal antibody was purified from tissue culture supernatant or ascites by affinity chromatography.

Immunogène: Phosphorylated Human WIP Peptide

Clone: K32-824

Isotype: IgG1 kappa

Information d'application

Volume d'échantillon: 20 μL

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Aqueous buffered solution containing BSA and ≤0.09 % sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C

Stockage commentaire: Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze. The antibody was conjugated to Alexa Fluor® 647 under optimum conditions, and unreacted Alexa Fluor® 647 was removed.

Détails sur WIPF1

Antigène: WIPF1 (WAS/WASL Interacting Protein Family, Member 1 (WIPF1))

Autre désignation: WIP (WIPF1 Produits)

Synonymes: anticorps WASPIP, anticorps PRPL-2, anticorps WIP, anticorps AI115543, anticorps D2Ertd120e, anticorps Waspip, anticorps Wip, anticorps WAS/WASL interacting protein family member 1, anticorps WAS/WASL interacting protein family, member 1, anticorps WIPF1, anticorps Wipf1

Sujet: Wiskott-Adrich syndrome protein (WASP)-Interacting Protein (WIP) is a member of the verprolin family of proteins that regulate cytoskeletal organization in a wide variety of cellular activities, including endocytosis, cellular adhesion and migration, mast cell degranulation, and lymphocyte activation. The 503-amino acid WIP protein contains binding sites for actin (globular and filamentous) and other proteins that are involved in the regulation of actin polymerization, such as WASP, N-WASP, profilin, cortactin, Hck, and NCK. As its functions imply, WIP is localized in actin-rich cell structures. The K32-824 monoclonal antibody recognizes the phosphorylated serine 488 (pS488) of human WIP. The orthologous phosphorylation sites in mouse and rat WIP are S478 and S472, respectively.
Synonyms: PRPL-2 protein, WAIP, WASIP, WASPIP

Pathways: Signalisation RTK