CD42b anticorps

N° du produit ABIN1177329

Détail du produit anti-CD42b anticorps

Antigène: CD42b (GP1BA) (Glycoprotein Ib (Platelet), alpha Polypeptide (GP1BA))

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp CD42b est non-conjugé

Application: Flow Cytometry (FACS), Functional Studies (Func)

Marque: BD Pharmingen™

Purification: The monoclonal antibody was purified from tissue culture supernatant or ascites by affinity chromatography.

Stérilité: 0.2 μm filtered

niveau d'endotoxine: Endotoxin level is ≤ 0.01 EU/μg (≤ 0.001 ng/μg) of protein as determined by the LAL assay.

Clone: HIP1

Isotype: IgG1 kappa

Information d'application

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1.0 mg/mL

Buffer: No azide/low endotoxin: Aqueous buffered solution containing no preservative, 0.2μm sterile filtered.

Agent conservateur: Azide free

Stock: 4 °C

Stockage commentaire: Store undiluted at 4°C. This preparation contains no preservatives, thus it should be handled under aseptic conditions.

Détails sur CD42b

Antigène: CD42b (GP1BA) (Glycoprotein Ib (Platelet), alpha Polypeptide (GP1BA))

Autre désignation: CD42B (GP1BA Produits)

Synonymes: anticorps BDPLT1, anticorps BDPLT3, anticorps BSS, anticorps CD42B, anticorps CD42b-alpha, anticorps DBPLT3, anticorps GP1B, anticorps GPIbA, anticorps VWDP, anticorps GP1BA, anticorps GPIba, anticorps GPIbalpha, anticorps glycoprotein Ib platelet alpha subunit, anticorps glycoprotein Ib (platelet), alpha polypeptide, anticorps glycoprotein 1b, alpha polypeptide, anticorps GP1BA, anticorps Gp1ba

Sujet: The HIP1 monoclonal antibody specifically binds to CD42b. CD42b is also known as the Platelet glycoprotein Ib alpha chain that is encoded by the GP1BA gene. CD42b is disulfide bonded to CD42c to form a 170 kDa heterodimer, GPIb. GPIb forms a noncovalent complex with CD42a and CD42d (CD42 complex) that is expressed on platelets and megakaryocytes. The CD42 complex serves as the von Willebrand Factor (vWF) surface receptor involved in the adhesion of platelets to the subendothelium of damaged vascular walls. HIP1 inhibits the ristocetin-dependent binding of vWF to platelets and partially inhibits collagen-induced aggregation.
Synonyms: GP1BA, GPIbalpha, GP-Ib alpha, GPIb-alpha, CD42b-alpha, Glycocalicin, BSS