KIR2DL3 anticorps

N° du produit ABIN118908

Détail du produit anti-KIR2DL3 anticorps

Antigène: KIR2DL3 (Killer Cell Immunoglobulin-Like Receptor, Two Domains, Long Cytoplasmic Tail, 3 (KIR2DL3))

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp KIR2DL3 est non-conjugé

Application: Western Blotting (WB), Flow Cytometry (FACS), Immunoprecipitation (IP)

Specificité: This antibody recognises the CD158b cell surface antigen. This antibody also recognises a 50 kDa molecule, which is highly homologous to p58.2 in the extracellular domain, but has a shorter cytoplasmic tail.

Purification: Purified

Immunogène: NK cell clone E57. Spleen cells from immunised BALB/c mice were fused with cells of the mouse P3UI myeloma cell line.

Clone: GL183

Isotype: IgG1

Information d'application

Indications d'application: Flow cytometry: 1/10 - 1/50, Use 10 μL of the suggested working dilution to label 10^6 cells in 100 μL. Immunoprecipitation.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Stockage

Concentration: 1.0 mg/mL

Buffer: PBS containing 0.09 % Sodium Azide and 0.1 % Bovine Serum Albumin

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freezing and thawing.

Stock: 4 °C/-20 °C

Stockage commentaire: Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Détails sur KIR2DL3

Antigène: KIR2DL3 (Killer Cell Immunoglobulin-Like Receptor, Two Domains, Long Cytoplasmic Tail, 3 (KIR2DL3))

Autre désignation: CD158b / KIR2DL3 (KIR2DL3 Produits)

Synonymes: anticorps CD158B2, anticorps CD158b, anticorps GL183, anticorps KIR-023GB, anticorps KIR-K7b, anticorps KIR-K7c, anticorps KIRCL23, anticorps NKAT, anticorps NKAT2, anticorps NKAT2A, anticorps NKAT2B, anticorps p58, anticorps killer cell immunoglobulin like receptor, two Ig domains and long cytoplasmic tail 3, anticorps KIR2DL3

Sujet: CD158b is a 58kD glycoprotein expressed by a subset of NK cells (also known as p58.2 antigen). The antigen is a members of the newly described natural killer cell receptor family. CD158b functions as a receptor specific for HLA Class I molecules, including Cw3 and related HLA-C alleles. This antibody can restore the lysis by human NK clones of otherwise lysis protected targets expressing Cw3.Synonyms: KIRCL23, Killer cell immunoglobulin-like receptor 2DL3, MHC class I NK cell receptor, NKAT2a, NKAT2b, Natural killer-associated transcript 2

ID gène: 3804

NCBI Accession: NP_056952

UniProt: P43628

Pathways: Cancer Immune Checkpoints