PTH1R anticorps

N° du produit ABIN122361

Détail du produit anti-PTH1R anticorps

Antigène: PTH1R (Parathyroid Hormone 1 Receptor (PTH1R))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp PTH1R est non-conjugé

Application: Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Specificité: The antibody reacts with Parathyroid Hormone Receptor Type 1 (PTHR1) (Family: GPCR, Subfamily: Parathyroid hormone)

Purification: Peptide immunogen affinity column

Immunogène: Synthetic peptide - KLH conjugated

Information d'application

Indications d'application: Immunohistochemistry on paraffin embedded sections: 2-4 μg/mL Antigen retrieval: Steam slides in 0.01 M sodium citrate buffer, pH 6.0, at 99-100 °C for 20 min. Remove from heat and let stand at room temperature in buffer for 20 min. Rinse in 1x TBS with Tween (TBST) for 1 min. at room temperature.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. Further Comments: This product was originally produced by MBL International.

Restrictions: For Research Use only

Stockage

Concentration: 1.0 mg/mL

Buffer: PBS, pH 7.7 containing 0.09 % sodium azide

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C/-80 °C

Stockage commentaire: Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -70 °C for longer. Avoid repeated freezing and thawing.
Shelf life: one year from despatch.

Date de péremption: 12 months

Détails sur PTH1R

Antigène: PTH1R (Parathyroid Hormone 1 Receptor (PTH1R))

Autre désignation: PTH Receptor 1 (PTH1R Produits)

Synonymes: anticorps PFE, anticorps PTHR, anticorps PTHR1, anticorps PPR, anticorps Pthr, anticorps Pthr1, anticorps pthr1, anticorps zPTH1R, anticorps PTHrel, anticorps PTH1, anticorps PTH, anticorps parathyroid hormone 1 receptor, anticorps parathyroid hormone 1 receptor a, anticorps PTH1R, anticorps Pth1r, anticorps pth1ra

Sujet: PTHR1, a Parathyroid Hormone Receptor, mediates PTH-dependent regulation of mineral-ion homeostasis. It also mediates the paracrine action of PTHRP in endochondral bone formation. Mutations in this receptor are responsible for disorders of calcium and bone metabolism such as chondrodysplasia, hypercalcemia, and chronic renal failure. Three promoters, P1, P2, and P3, regulate the expression of PTHR. PTHR1 has been reported to be expressed in bone, breast, brain, colon, GI, kidney, liver, placenta, skin, umbilical cord, and uterus. ESTs have been isolated from B-cell/lung/testis, brain, breast, fetus, heart, heart / melanocyte / uterus, kidney, liver / spleen, lung, placenta, and testis librariesSynonyms: PTH/PTHrP type I receptor, PTH1R, PTHR, PTHR1, Parathyroid hormone 1 receptor, Parathyroid hormone/parathyroid hormone-related peptide receptor

ID gène: 5745

UniProt: Q03431

Pathways: Regulation of Carbohydrate Metabolic Process