ADCYAP1R1 anticorps (N-Term)

N° du produit ABIN122519

Détail du produit anti-ADCYAP1R1 anticorps

Antigène: ADCYAP1R1 (Adenylate Cyclase Activating Polypeptide 1 (Pituitary) Receptor Type I (ADCYAP1R1))

Épitope: N-Term

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp ADCYAP1R1 est non-conjugé

Application: Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Specificité: Reacts with PACAP Receptor Type 1 (Family: GPCR, subfamily: Vasoactive intestinal polypeptide)

Purification: Peptide immunogen affinity column

Immunogène: Synthetic peptide - KLH conjugated

Information d'application

Indications d'application: Immunohistochemistry with formalin fixed paraffin embedded tissues: 7 μg/mL Antigen retrieval: Steam slides in 0.01 M sodium citrate buffer, pH 6.0, at 99-100 °C for 20 min. Remove from heat and let stand at room temperature in buffer for 20 min. Rinse in 1x TBS with Tween (TBST) for 1 min. at room temperature.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. Further Comments: This product was originally produced by MBL International.

Restrictions: For Research Use only

Stockage

Concentration: 1.0 mg/mL

Buffer: PBS containing 0.09 % Sodium Azide as preservative

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C/-20 °C

Stockage commentaire: Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C to -70 °C forlonger. Avoid repeated freezing and thawing.
Shelf life: one year from despatch.

Date de péremption: 12 months

Détails sur ADCYAP1R1

Antigène: ADCYAP1R1 (Adenylate Cyclase Activating Polypeptide 1 (Pituitary) Receptor Type I (ADCYAP1R1))

Autre désignation: PACAP Type I Receptor (ADCYAP1R1 Produits)

Synonymes: anticorps PAC1, anticorps PAC1R, anticorps PACAPR, anticorps PACAPRI, anticorps 2900024I10Rik, anticorps AI846590, anticorps PACAP1-R, anticorps pac1, anticorps pacapr, anticorps pacapri, anticorps PAC1-R, anticorps PACAP-R1, anticorps PACAP-R1A, anticorps PACAPR1, anticorps PACAPR1A, anticorps adcyap1r1, anticorps adcyap1r1-A, anticorps ADCYAP1R1, anticorps ADCYAP receptor type I, anticorps adenylate cyclase activating polypeptide 1 receptor 1, anticorps adenylate cyclase activating polypeptide 1 (pituitary) receptor type I, anticorps ADCYAP receptor type 1, anticorps adenylate cyclase activating polypeptide 1a (pituitary) receptor type I, anticorps adenylate cyclase activating polypeptide 1 (pituitary) receptor type I S homeolog, anticorps ADCYAP1R1, anticorps Adcyap1r1, anticorps adcyap1r1, anticorps adcyap1r1a, anticorps adcyap1r1.S

Sujet: The PACAP receptor type 1, a member of the vasoactive intestinal polypeptide subfamily, binds the hormone pituitary adenylate cyclase activating polypeptide (PACAP) with high affinity. PACAP is involved in stimulating the secretion of insulin, catecholamines, ACTH, and growth hormone. Additionally, PACAP appears to function as a neuromodulator/ neurotransmitter in the central and peripheral nervous systems. Two start codons are reported in literature, one (nt 74-76) results in a 525-amino acid protein with a signal peptide of 77 amino acids encoded by nt 74-304 and the second (nt 245-247) initiates a 468-amino acid protein with a signal peptide of 20-amino acids encoded by nt 245-304. The efficiency of these two start codons is not known. PACAP receptor type 1 expression has been documented in adipose, adrenal, bone, brain, colon, ganglion, heart, lung, ovary, pancreas, placenta, spleen, and uterus. ESTs have been isolated from brain and nerve libraries.Synonyms: ADCYAP1R1, Pituitary adenylate cyclase-activating polypeptide type I receptor

ID gène: 117

UniProt: P41586

Pathways: Neurotrophin Signaling Pathway, cAMP Metabolic Process, Regulation of Carbohydrate Metabolic Process