CDC7 anticorps (Kinase Domain)

N° du produit ABIN122614

Cet anticorps Lapin Polyclonal détecte spécifiquement CDC7 dans IHC (p). Il présente une réactivité avec des échantillons de Humain.

Aperçu rapide pour CDC7 anticorps (Kinase Domain) (ABIN122614)

Antigène: CDC7 (Cell Division Cycle 7 (CDC7))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp CDC7 est non-conjugé

Application: Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Détail du produit anti-CDC7 anticorps

Épitope: Kinase Domain

Specificité: Reacts with CDC7-Related Protein Kinase (CDC7L1) (family: Protein Kinase, subfamily: CDC7)

Attributs du produit: Synonyms: CDC7L1, CDC7-related kinase, HsCdc7, huCdc7, Cell division cycle 7-related protein kinase

Purification: Peptide immunogen affinity column

Immunogène: Synthetic peptide - KLH conjugatedEpitope: Kinase domain of humanGenename: CDC7Remarks: The immunizing peptide shows 63 % identity (79 % similarity) with mouse.

Information d'application

Indications d'application: Immunohistochemistry on paraffin embedded sections: 5,2 μg/mLntigen retrieval: Steam slides in 0.01 M sodium citrate buffer, pH 6.0, at 99-100C for 20 min. Remove fromheat and let stand at room temperature in buffer for 20 min. Rinse in 1x TBS with Tween(TBST) for 1 min. at room temperature.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Stockage

Concentration: 1.0 mg/mL

Buffer: PBS, pH 7.7, containing 0.01 % sodium azide

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C/-80 °C

Stockage commentaire: Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -70 °C for longer. Avoid repeated freezing and thawing.
Shelf life: one year from despatch.

Date de péremption: 12 months

Détails sur CDC7

Antigène: CDC7 (Cell Division Cycle 7 (CDC7))

Autre désignation: CDC7

Sujet: CDC7L1, CDC7 type protein kinase, regulates firing of the origins of initiation in DNA replication. CDC7L1 forms a complex with a Dbf4-related regulatory subunit to generate an active kinase. Mini-chromosome maintenance protein (MCM) is the major physiological target of Cdc7L1. At least three mRNA variants have been reported. Overexpression of the CDC7L1 protein may be associated with neoplastic transformation for some tumors. CDC7L1 has been documented in a wide range of tissues. One variant is expressed ubiquitously in human tissues while at least one other has been shown to be testis-specific. ESTs have been isolated from several tissue libraries, including normal embryo, gallbladder, lymph node and thymus and cancerous duodenum and embryo.Synonyms: CDC7-related kinase, CDC7L1, Cell division cycle 7-related protein kinase, HsCdc7, huCdc7

ID gène: 8317

UniProt: O00311

Pathways: Mitotic G1-G1/S Phases, DNA Replication