NR5A1 anticorps (Internal Region)

N° du produit ABIN122633

Détail du produit anti-NR5A1 anticorps

Antigène: NR5A1 (Nuclear Receptor Subfamily 5, Group A, Member 1 (NR5A1))

Épitope: Internal Region

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp NR5A1 est non-conjugé

Application: Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Specificité: This antibody detects Steroidogenic factor 1. BLAST analysis of the peptide immunogen showed no homology with other human proteins, except TRIM23 (47 %).

Réactivité croisée (Details): Species reactivity (tested):Human

Attributs du produit: Synonyms: STF-1, SF-1, NR5A1, AD4BP, FTZF1, SF1, Nuclear receptor subfamily 5 group A member 1,Adrenal 4-binding protein, Steroid hormone receptor Ad4BP, Fushi tarazu factor homolog 1

Purification: Immunoaffinity chromatography

Immunogène: Synthetic peptide - KLH conjugatedEpitope: internal domain of humanGenename: NR5A1Remarks: The immunizing peptide shows 88 % identity (100 % similarity) with mouse and88 % identity (100 % similarity) with rat.

Information d'application

Indications d'application: Immunohistochemistry with formalin fixed paraffin embedded tissues: 2-18 μg/mLAntigen retrieval: Steam slides in 0.01 M sodium citrate buffer, pH 6.0, at 99-100C for 20 min. Remove fromheat and let stand at room temperature in buffer for 20 min. Rinse in 1x TBS with Tween(TBST) for 1 min. at room temperature.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Stockage

Concentration: 1.0 mg/mL

Buffer: PBS containing 0.09 % Sodium azide

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C/-80 °C

Stockage commentaire: Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -70 °C for longer. Avoid repeated freezing and thawing.
Shelf life: one year from despatch.

Date de péremption: 12 months

Détails sur NR5A1

Antigène: NR5A1 (Nuclear Receptor Subfamily 5, Group A, Member 1 (NR5A1))

Autre désignation: Steroidogenic Factor 1 (NR5A1 Produits)

Synonymes: anticorps AD4BP, anticorps ELP, anticorps FTZ1, anticorps FTZF1, anticorps POF7, anticorps SF-1, anticorps SF1, anticorps SPGF8, anticorps SRXY3, anticorps Ad4BP, anticorps ELP-3, anticorps Ftz-F1, anticorps Ftzf1, anticorps Ad4BP/SF-1, anticorps Ad4bp, anticorps Sf-1, anticorps NR5A1, anticorps sf-1, anticorps elp, anticorps sf1, anticorps ftz1, anticorps ad4bp, anticorps ftzf1, anticorps SF-1/Ad4BP, anticorps SI:zC167P9.2, anticorps ff1d, anticorps nr5a2l, anticorps nuclear receptor subfamily 5 group A member 1, anticorps nuclear receptor subfamily 5, group A, member 1, anticorps nuclear receptor subfamily 5 group A member 1 L homeolog, anticorps nuclear receptor subfamily 6 group A member 1, anticorps nuclear receptor subfamily 5, group A, member 1b, anticorps NR5A1, anticorps Nr5a1, anticorps nr5a1.L, anticorps nr5a1, anticorps NR6A1, anticorps nr5a1b

Sujet: Steroidogenic factor 1 (SF-1), a NR5 Fushi Tarazu-Like Receptor, has been shown to affect sexual differentiation, steroid metabolism, and neural development. SF-1 binds as a monomer and regulates all steroidogenic p450 genes, Mullerian inhibiting substance, the gonadotrophins, the ACTH receptor, oxytocin, nuclear receptor DAX-1, and several other genes. Four alternatively spliced isoforms of SF-1 have been isolated in mice, and they differ at the N and C termini but are identical in the DNA-binding domain. SF-1 expression has been documented in human brain, adrenal, spleen, liver, heart, ovary, testis, and placenta. ESTs have been isolated from human tissue libraries, including cancerous adrenal and normal lung and testis.Synonyms: AD4BP, Adrenal 4-binding protein, FTZF1, Fushi tarazu factor homolog 1, NR5A1, Nuclear receptor subfamily 5 group A member 1, SF-1, SF1, STF-1, Steroid hormone receptor Ad4BP

ID gène: 2516

UniProt: Q13285

Pathways: Nuclear Receptor Transcription Pathway, Steroid Hormone Mediated Signaling Pathway, Maintenance of Protein Location